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L-Norvaline - 99%, high purity , CAS No.6600-40-4

12 Citations

≥99%

CAS#: 6600-40-4
Formula: C₅H₁₁NO₂
Molecular Weight: 117.15
Beilstein Registry Number: 1721162
EC Number: 229-543-3
MDL number: MFCD00064421
PubChem CID: 65098
PubChem SID: 488183665

Item Number

N106215

Grouped product items
SKU	Size	Availability	Price
N106215-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$24.90
N106215-5g	5g	In stock	$65.90
N106215-25g	25g	In stock	$294.90
N106215-100g	100g	In stock	$1,061.90
N106215-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$4,778.90

View related series

Chemical Biology Peptide chemistry

Basic Description

Synonyms	Pentanoic acid, 2-amino-, (S)- \| Q418707 \| C01826 \| DB04185 \| A70UKS48FE \| L-2-aminopentanoate \| BDBM50357215 \| Valeric acid, 2-amino- \| AM20100599 \| EINECS 229-543-3 \| Norvaline (VAN) \| HY-Y0399 \| MFCD00064421 \| SNDPXSYFESPGGJ-BYPYZUCNSA-N \| (2S)-2-amino
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	L-Norvaline enhances NO production from activated macrophages.
Shipped In	Normal
Note	N106215-1g卖完停产，不再备货
Product Description	L-Norvaline enhances NO production from activated macrophages. arginase inhibitor Application L-Norvaline enhances NO production from activated macrophages. It is known to promote tissue regeneration and muscle growth and become a precursor in the penicillin biosynthetic pathway. It also can be used for nutrition agent and drug synthesis. For example: it can react with phthalic acid anhydride to get N,N-phthaloyl-L-norvaline.

Associated Targets(Human)

SLC36A1 Tchem Proton-coupled amino acid transporter 1 (0 Activities)

Discover Target: SLC36A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC1A5 Tchem Neutral amino acid transporter B(0) (0 Activities)

Discover Target: SLC1A5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC36A1 Tchem Proton-coupled amino acid transporter 1 (102 Activities)

Discover Target: SLC36A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488183665
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488183665
IUPAC Name	(2S)-2-aminopentanoic acid
INCHI	InChI=1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChi Key	SNDPXSYFESPGGJ-BYPYZUCNSA-N
Canonical SMILES	CCCC(C(=O)O)N
Isomeric SMILES	CCC[C@@H](C(=O)O)N
WGK Germany	3
PubChem CID	65098
Molecular Weight	117.15
Beilstein	1721162
Reaxy-Rn	1721162

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot Number	Certificate Type	Date	Item
D2321415	Certificate of Analysis	Jul 07, 2022	N106215
D2321421	Certificate of Analysis	Jul 07, 2022	N106215
D2321425	Certificate of Analysis	Jul 07, 2022	N106215
I2224425	Certificate of Analysis	Jul 07, 2022	N106215
I2224427	Certificate of Analysis	Jul 07, 2022	N106215
I2224428	Certificate of Analysis	Jul 07, 2022	N106215
I2224555	Certificate of Analysis	Jul 07, 2022	N106215
C2211173	Certificate of Analysis	Jul 31, 2021	N106215

Chemical and Physical Properties

Solubility	Soluble in water (almost transparency), 10.5 g/100 mL (18°C).
Specific Rotation[α]	+23.0 to +26.0 deg(C=10, 6mol/L HCl)
Melt Point(°C)	＞300°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
Reaxy-Rn	1721162
Merck Index	6716

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Dongsheng Xu,Elena Sánchez-López,Qiqin Wang,Zhengjin Jiang,María Luisa Marina. (2020-03-04) Determination of l-norvaline and l-tryptophan in dietary supplements by nano-LC using an O-[2-(methacryloyloxy)-ethylcarbamoyl]-10,11-dihydroquinidine-silica hybrid monolithic column.. Journal of pharmaceutical analysis, 10 ((1)): (70-77). [PMID:32123601]
2. Rongrong Zhu, Yan Yuan, Rourou Qi, Jianying Liang, Yan Shi, Hongbo Weng. (2023) Quantitative profiling of carboxylic compounds by gas chromatography-mass spectrometry for revealing biomarkers of diabetic kidney disease. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1231 (30): (123930). [PMID:38029665] [10.1016/j.jchromb.2023.123930]
3. Shaobo Yang, Hong Yang, Yanlei Huang, Gong Chen, Chun Shen, Shan Zheng. (2023) Serum Metabolomic Signatures of Hirschsprung’s Disease Based on GC–MS and LC–MS. JOURNAL OF PROTEOME RESEARCH, 22 (7): (2307–2318). [PMID:37235583] [10.1021/acs.jproteome.3c00008]
4. Xiao-xiao Zheng, Ding-xiang Li, Ya-ting Li, Yu-lang Chen, Yan-lin Zhao, Shuai Ji, Meng-zhe Guo, Yan Du, Dao-Quan Tang. (2023) Mulberry leaf water extract alleviates type 2 diabetes in mice via modulating gut microbiota-host co-metabolism of branched-chain amino acid. PHYTOTHERAPY RESEARCH, [PMID:37013717] [10.1002/ptr.7822]
5. Kai Cai, Yongpeng Zhao, Zongjing Kang, Shuling Wang, Alan L. Wright, Xianjun Jiang. (2023) Environmental pseudotargeted metabolomics: A high throughput and wide coverage method for metabolic profiling of 1000-year paddy soil chronosequences. SCIENCE OF THE TOTAL ENVIRONMENT, 858 (159978). [PMID:36343812] [10.1016/j.scitotenv.2022.159978]
6. Yaning Qin, Zhaoyue Yan, Rui Liu, Chaojie Qu, Haichen Mao, Lingbo Qu, Ran Yang. (2021) Ultra-sensitive detection of ATP in serum and lysates based on nitrogen-doped carbon dots. LUMINESCENCE, 36 (7): (1584-1591). [PMID:33900056] [10.1002/bio.4061]
7. Qu Fei, Yan Hang, Li Kexin, You Jinmao, Han Wenli. (2020) A covalent organic framework–MnO2 nanosheet system for determination of glutathione. JOURNAL OF MATERIALS SCIENCE, 55 (23): (10022-10034). [PMID:] [10.1007/s10853-020-04754-9]
8. Hao-Hua Deng, Xiao-Qiong Shi, Hua-Ping Peng, Quan-Quan Zhuang, Yu Yang, Ai-Lin Liu, Xing-Hua Xia, Wei Chen. (2018) Gold Nanoparticle-Based Photoluminescent Nanoswitch Controlled by Host–Guest Recognition and Enzymatic Hydrolysis for Arginase Activity Assay. ACS Applied Materials & Interfaces, 10 (6): (5358–5364). [PMID:29373021] [10.1021/acsami.7b19513]
9. Fei Qu, Yanqun Liu, Haili Lao, Yaping Wang, Jinmao You. (2017) Colorimetric detection of heparin with high sensitivity based on the aggregation of gold nanoparticles induced by polymer nanoparticles. NEW JOURNAL OF CHEMISTRY, 41 (19): (10592-10597). [PMID:] [10.1039/C7NJ02381B]
10. Yuanhao Cai, Yulong Chen, Qijie Li, Liang Li, Haoxin Huang, Suying Wang, Weixing Wang. (2017) CO2 Hydrate Formation Promoted by a Natural Amino Acid l-Methionine for Possible Application to CO2 Capture and Storage. Energy Technology, 5 (8): (1195-1199). [PMID:] [10.1002/ente.201600731]
11. Donglin Jia, Lu Wang, Yudong Gao, Lina Zou, Baoxian Ye. (2016) Electrochemical behavior of metribuzin based on l-Norvaline modified electrode and its sensitive determination. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 764 (56). [PMID:] [10.1016/j.jelechem.2016.01.016]
12. Yan Du,Bing-Ju Xu,Xu Deng,Xiao-Wen Wu,Yin-Jie Li,Shi-Rui Wang,Yi-Nan Wang,Shuai Ji,Meng-Zhe Guo,Dong-Zhi Yang,Dao-Quan Tang. (2019-01-02) Predictive metabolic signatures for the occurrence and development of diabetic nephropathy and the intervention of Ginkgo biloba leaves extract based on gas or liquid chromatography with mass spectrometry.. Journal of pharmaceutical and biomedical analysis, 166 (30-39). [PMID:30599279]

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