Inhibits ulcer formation by the reduction of gastric acid secretion. Inhibits intestinal absorption of L-phenylalanine in rats. Enhances Na + excretion in urine. Active in vitro and in vivo .
Storage Temp
Argon charged
Shipped In
Normal
Grade
Moligand™
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
L-Phenylalaninol reduces the secretion of gastric acid and inhibits intestinal absorption of L-phenylalanine. Reacts with nitriles to form oxazolines which are useful in Pd-catalyzed allylic substitution. Also employed in amidation for chiral resolutionand NADH modeling.
1.H Hashizume,T Miyamae,T Morikawa,M Hagiwara. (1992-11-01) Effects of phenylalaninol on centrally induced gastric acid secretion.. Chemical & pharmaceutical bulletin, 40 ((11)):(3113-3114). [PMID:1477931]
2.W W Mak,J T Wong. (1980-12-01) Relationship between membrane fluidity and capping of receptors for concanavalin A.. Canadian journal of biochemistry, 58 ((12)):(1421-1429). [PMID:6265046]
3.Violetta Constantinou-Kokotou,Anna Peristeraki,Christoforos G Kokotos,David A Six,Edward A Dennis. (2005-01-07) Synthesis and activity of 2-oxoamides containing long chain beta-amino acids.. Journal of peptide science : an official publication of the European Peptide Society, 11 ((7)):(431-435). [PMID:15635664]
4.Salvatore Caccamese,Salvatore Bianca,Guy T Carter. (2007-06-15) Direct high-performance liquid chromatographic separation of the enantiomers of an aromatic amine and four aminoalcohols using polysaccharide chiral stationary phases and acidic additive.. Chirality, 19 ((8)):(647-653). [PMID:17568428]
5.Eun Na Rae Cho,Yinan Li,Hee Jin Kim,Myung Ho Hyun. (2011-03-09) A colorimetric chiral sensor based on chiral crown ether for the recognition of the two enantiomers of primary amino alcohols and amines.. Chirality, 23 ((4)):(349-353). [PMID:21384440]
6.Ruriko Sekiya-Aoyama,Yoshinori Arisaka,Nobuhiko Yui. (2020-02-15) Mobility Tuning of Polyrotaxane Surfaces to Stimulate Myocyte Differentiation.. Macromolecular bioscience, 20 ((4)):(e1900424-e1900424). [PMID:32058659]
7.B Weiss,K S Hui,M Hui,A Lajtha. (1988-10-01) Aminothiols: synthesis and effect on chicken brain aminopeptidases.. Research communications in chemical pathology and pharmacology, 62 ((1)):(113-123). [PMID:3205972]
8.W W Mak,L Pinteric,J T Wong. (1980-09-01) Enhanced sensitivity of tumorigenic cells to rapid rounding induced by phenylalaninol.. Canadian journal of biochemistry, 58 ((9)):(737-744). [PMID:6257353]
9.G P Zecchini,M P Paradisi,I Torrini,S Spisani. (1995-09-01) Chemotactic peptide analogues. Synthesis and chemotactic activity of N-formyl-Met-Leu-Phe analogues containing (S)-phenylalaninol derivatives.. Archiv der Pharmazie, 328 ((9)):(673-676). [PMID:7487425]
10.Yoshinori Arisaka,Nobuhiko Yui. (2017-04-13) Tethered bone morphogenetic protein-2 onto sulfonated-polyrotaxane based surfaces promotes osteogenic differentiation of MC3T3-E1 cells.. Journal of biomaterials science. Polymer edition, 28 ((10-12)):(974-985). [PMID:28402171]
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A2306838