L-Theanine - 99%, high purity , CAS No.3081-61-6

12 Citations
  • ≥99%
Item Number
T106217
Grouped product items
SKUSizeAvailabilityPrice Qty
T106217-1g
1g
In stock
$57.90
T106217-5g
5g
In stock
$166.90
T106217-25g
25g
In stock
$748.90
T106217-100g
100g
In stock
$2,693.90

Amino acid analog of glutamine found in green tea

Basic Description

SynonymsCCRIS 7326 | DTXSID80184817 | THEANINE, L- | L-Theanine (Ngamma-ethyl-L-glutamine) | N-Ethyl L-glutamine | NSC 21308 | Glutamine, N-ethyl-, L- | H-Glu(NHEt)-OH | N?-Ethyl-L-glutamine | MFCD00059653 | CCG-38778 | DB12444 | s3852 | SPECTRUM1505254 | UNII-80
Specifications & Purity≥99%
Biochemical and Physiological MechanismsAmino acid analog of glutamine, commonly found in green tea. Binds to AMPA, kainate, NMDA and group I mGlu receptors. Displays neuroprotective and cognitive enhancing effects. Also shown to modify self-renewal properties of cancer stem cells.
Shipped InNormal
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(Human)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488189744
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488189744
IUPAC Name (2S)-2-amino-5-(ethylamino)-5-oxopentanoic acid
INCHI InChI=1S/C7H14N2O3/c1-2-9-6(10)4-3-5(8)7(11)12/h5H,2-4,8H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1
InChi Key DATAGRPVKZEWHA-YFKPBYRVSA-N
Canonical SMILES CCNC(=O)CCC(C(=O)O)N
Isomeric SMILES CCNC(=O)CC[C@@H](C(=O)O)N
WGK Germany 3
PubChem CID 439378
Molecular Weight 174.2
Reaxy-Rn 1725586

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot NumberCertificate TypeDateItem
B2309504Certificate of AnalysisJan 05, 2023 T106217
B2309505Certificate of AnalysisJan 05, 2023 T106217
B2309506Certificate of AnalysisJan 05, 2023 T106217
B2309508Certificate of AnalysisJan 05, 2023 T106217
B2309509Certificate of AnalysisJan 05, 2023 T106217
B2309510Certificate of AnalysisJan 05, 2023 T106217
B2309511Certificate of AnalysisJan 05, 2023 T106217
B2309514Certificate of AnalysisJan 05, 2023 T106217
C2406048Certificate of AnalysisJan 05, 2023 T106217
H2328048Certificate of AnalysisJan 05, 2023 T106217
I2228177Certificate of AnalysisOct 10, 2022 T106217
G2229161Certificate of AnalysisAug 05, 2022 T106217

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Chemical and Physical Properties

Specific Rotation[α]8 ° (C=5, H2O)
Melt Point(°C)207°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H317:May cause an allergic skin reaction

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P501:Dispose of contents/container to ...

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

WGK Germany 3
Reaxy-Rn 1725586

Related Documents

Citations of This Product

1. Yuqing Zhong, Yongling Lu, Lishuang Lv.  (2023)  Theanine in Tea: An Effective Scavenger of Single or Multiple Reactive Carbonyl Species at the Same Time.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  71  (45): (17153–17162).  [PMID:37906124]
2. Guorong Ma, Pengzheng Luo, Ruiqiang Xu, Rui Ma, Lei Qiu, Chenran Xu, Rang Yang, Yating Li, Zhihao Zhao, Ling Huang, Yanhui Yang, Pei Wang.  (2023)  Improving the profile and reliability of cytoplasmic proteins from M. tuberculosis using biomimetic affinity chromatography coupled with LC-MS/MS analysis.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,  1225  (123756).  [PMID:37236071]
3. Anqi Peng, Keke Yu, Shuwei Yu, Yingying Li, Hao Zuo, Ping Li, Juan Li, Jianan Huang, Zhonghua Liu, Jian Zhao.  (2023)  Aluminum and Fluoride Stresses Altered Organic Acid and Secondary Metabolism in Tea (Camellia sinensis) Plants: Influences on Plant Tolerance, Tea Quality and Safety.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  24  (5): (4640).  [PMID:36902071]
4. Jingna Yan, Anxia Lu, Jirui Kun, Bei Wang, Yiwen Miao, Yingjuan Chen, Chi-Tang Ho, Qing Meng, Huarong Tong.  (2023)  Characterization of triterpenoids as possible bitter-tasting compounds in teas infected with bird’s eye spot disease.  FOOD RESEARCH INTERNATIONAL,  167  (112643).  [PMID:37087235]
5. Dingding Liu, Kang Wei, Chenyu Zhang, Haoran Liu, Yang Gong, Yuanyuan Ye, Jiedan Chen, Mingzhe Yao, Liang Chen, Chunlei Ma.  (2023)  The potential effects of chlorophyll-deficient mutation and tree_age on the accumulation of amino acid components in tea plants.  FOOD CHEMISTRY,  411  (135527).  [PMID:36701915]
6. Chengxiang Chu, Xianfeng Wang, Yuanyi Deng, Yi Ma, Chengyue Zou, Mei Yang, Huibo Luo, Danqun Huo, Changjun Hou.  (2023)  Discrimination of Chinese green tea according to tea polyphenols using fluorescence sensor array based on Tb (III) and Eu (III) doped Zr (IV) metal–organic frameworks.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  292  (122380).  [PMID:36736046]
7. Yao Fan, Siying Che, Lei Zhang, Chunsong Zhou, Haiyan Fu, Yuanbin She.  (2022)  Dual channel sensor array based on ZnCdSe QDs – KMnO4: An effective tool for analysis of catechins and green teas.  FOOD RESEARCH INTERNATIONAL,  160  (111734).  [PMID:36076421]
8. Wang Zixi, Tang Yanfang, Long Lina, Zhang Huihua.  (2022)  Effects of Dietary L-Theanine on Growth Performance, Antioxidation, Meat Quality, and Intestinal Microflora in White Feather Broilers With Acute Oxidative Stress.  Frontiers in Veterinary Science,    [PMID:35812843]
9. Wang Ying, Li ZhiRong, Chen RongXiang.  (2022)  Simultaneous Determination of Metabolites Related to Arginine Metabolism in Rat plasma by Hydrophilic Interaction Chromatography–Tandem Mass Spectrometry.  JOURNAL OF CHROMATOGRAPHIC SCIENCE,  61  (3): (203-210).  [PMID:35704851]
10. Hui-Wen Gu, Xiao-Li Yin, Tian-Qin Peng, Yuan Pan, Hui-Na Cui, Zhi-Quan Li, Weiqing Sun, Baomiao Ding, Xian-Chun Hu, Zi-Hong Zhang, Zhi Liu.  (2022)  Geographical origin identification and chemical markers screening of Chinese green tea using two-dimensional fingerprints technique coupled with multivariate chemometric methods.  FOOD CONTROL,  135  (108795).  [PMID:]
11. Yan Huang, Dandan Pu, Zhilin Hao, Xiao Yang, Yuyu Zhang.  (2021)  The Effect of Prickly Ash (Zanthoxylum bungeanum Maxim) on the Taste Perception of Stewed Sheep Tail Fat by LC-QTOF-MS/MS and a Chemometrics Analysis.  Foods,  10  (11): (2709).  [PMID:34828990]
12. Yan-Qing Fu,Jie-Qiong Wang,Jian-Xin Chen,Fang Wang,Jun-Feng Yin,Liang Zeng,John Shi,Yong-Quan Xu.  (2020-06-17)  Effect of baking on the flavor stability of green tea beverages..  Food chemistry,  331  (127258-127258).  [PMID:32544652]

References

1. Dias TR et al..  (2019)  L-Theanine promotes cultured human Sertoli cells proliferation and modulates glucose metabolism..  Eur J Nutr,  58  (7): (2961-2970).  [PMID:31183510]
2. Yuqing Zhong, Yongling Lu, Lishuang Lv.  (2023)  Theanine in Tea: An Effective Scavenger of Single or Multiple Reactive Carbonyl Species at the Same Time.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  71  (45): (17153–17162).  [PMID:37906124]
3. Guorong Ma, Pengzheng Luo, Ruiqiang Xu, Rui Ma, Lei Qiu, Chenran Xu, Rang Yang, Yating Li, Zhihao Zhao, Ling Huang, Yanhui Yang, Pei Wang.  (2023)  Improving the profile and reliability of cytoplasmic proteins from M. tuberculosis using biomimetic affinity chromatography coupled with LC-MS/MS analysis.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,  1225  (123756).  [PMID:37236071]
4. Anqi Peng, Keke Yu, Shuwei Yu, Yingying Li, Hao Zuo, Ping Li, Juan Li, Jianan Huang, Zhonghua Liu, Jian Zhao.  (2023)  Aluminum and Fluoride Stresses Altered Organic Acid and Secondary Metabolism in Tea (Camellia sinensis) Plants: Influences on Plant Tolerance, Tea Quality and Safety.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  24  (5): (4640).  [PMID:36902071]
5. Jingna Yan, Anxia Lu, Jirui Kun, Bei Wang, Yiwen Miao, Yingjuan Chen, Chi-Tang Ho, Qing Meng, Huarong Tong.  (2023)  Characterization of triterpenoids as possible bitter-tasting compounds in teas infected with bird’s eye spot disease.  FOOD RESEARCH INTERNATIONAL,  167  (112643).  [PMID:37087235]
6. Dingding Liu, Kang Wei, Chenyu Zhang, Haoran Liu, Yang Gong, Yuanyuan Ye, Jiedan Chen, Mingzhe Yao, Liang Chen, Chunlei Ma.  (2023)  The potential effects of chlorophyll-deficient mutation and tree_age on the accumulation of amino acid components in tea plants.  FOOD CHEMISTRY,  411  (135527).  [PMID:36701915]
7. Chengxiang Chu, Xianfeng Wang, Yuanyi Deng, Yi Ma, Chengyue Zou, Mei Yang, Huibo Luo, Danqun Huo, Changjun Hou.  (2023)  Discrimination of Chinese green tea according to tea polyphenols using fluorescence sensor array based on Tb (III) and Eu (III) doped Zr (IV) metal–organic frameworks.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  292  (122380).  [PMID:36736046]
8. Yao Fan, Siying Che, Lei Zhang, Chunsong Zhou, Haiyan Fu, Yuanbin She.  (2022)  Dual channel sensor array based on ZnCdSe QDs – KMnO4: An effective tool for analysis of catechins and green teas.  FOOD RESEARCH INTERNATIONAL,  160  (111734).  [PMID:36076421]
9. Wang Zixi, Tang Yanfang, Long Lina, Zhang Huihua.  (2022)  Effects of Dietary L-Theanine on Growth Performance, Antioxidation, Meat Quality, and Intestinal Microflora in White Feather Broilers With Acute Oxidative Stress.  Frontiers in Veterinary Science,    [PMID:35812843]
10. Wang Ying, Li ZhiRong, Chen RongXiang.  (2022)  Simultaneous Determination of Metabolites Related to Arginine Metabolism in Rat plasma by Hydrophilic Interaction Chromatography–Tandem Mass Spectrometry.  JOURNAL OF CHROMATOGRAPHIC SCIENCE,  61  (3): (203-210).  [PMID:35704851]
11. Hui-Wen Gu, Xiao-Li Yin, Tian-Qin Peng, Yuan Pan, Hui-Na Cui, Zhi-Quan Li, Weiqing Sun, Baomiao Ding, Xian-Chun Hu, Zi-Hong Zhang, Zhi Liu.  (2022)  Geographical origin identification and chemical markers screening of Chinese green tea using two-dimensional fingerprints technique coupled with multivariate chemometric methods.  FOOD CONTROL,  135  (108795).  [PMID:]
12. Yan Huang, Dandan Pu, Zhilin Hao, Xiao Yang, Yuyu Zhang.  (2021)  The Effect of Prickly Ash (Zanthoxylum bungeanum Maxim) on the Taste Perception of Stewed Sheep Tail Fat by LC-QTOF-MS/MS and a Chemometrics Analysis.  Foods,  10  (11): (2709).  [PMID:34828990]
13. Yan-Qing Fu,Jie-Qiong Wang,Jian-Xin Chen,Fang Wang,Jun-Feng Yin,Liang Zeng,John Shi,Yong-Quan Xu.  (2020-06-17)  Effect of baking on the flavor stability of green tea beverages..  Food chemistry,  331  (127258-127258).  [PMID:32544652]

Solution Calculators