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Basic Description
| Synonyms | L-threonine|threonine|72-19-5|Threonin|(2S,3R)-2-amino-3-hydroxybutanoic acid|L-(-)-Threonine|(S)-Threonine|H-Thr-OH|DL-Threonine|2-amino-3-hydroxybutyric acid|Threonine, L-|Threonine (VAN)|80-68-2|Threoninum [Latin]|Treonina [Spanish]|thre|Threoninum|Tre |
|---|---|
| Specifications & Purity | Moligand™, 10mM in Water |
| Biochemical and Physiological Mechanisms | L-Threonine is considered to be an essential amino acid. L-Threonine is involved in the synthesis of mucin, a protein supporting intestinal function and integrity. L-Threonine is required for the performance of the immune system. It is also essential for |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
| Product Description | L-Threonine is a naturally occurring amino acid belonging to the aspartate family of amino acids. |
Associated Targets
DRD1 Tclin D(1A) dopamine receptor 0 Activities
ESR1 Tclin Estrogen receptor 0 Activities
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GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities
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HRH3 Tclin Histamine H3 receptor 0 Activities
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HDAC6 Tclin Histone deacetylase 6 0 Activities
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SLC6A2 Tclin Sodium-dependent noradrenaline transporter 0 Activities
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SLC6A3 Tclin Sodium-dependent dopamine transporter 0 Activities
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SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities
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PGR Tclin Progesterone receptor 0 Activities
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PDE3A Tclin cGMP-inhibited 3',5'-cyclic phosphodiesterase A 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities
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PDE4A Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4A 0 Activities
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PKM Tchem Pyruvate kinase PKM 0 Activities
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SLC16A10 Tbio Monocarboxylate transporter 10 0 Activities
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DRD3 Tclin D(3) dopamine receptor 0 Activities
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KDR Tclin Vascular endothelial growth factor receptor 2 0 Activities
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SLC1A5 Tchem Neutral amino acid transporter B(0) 0 Activities
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CHRM2 Tclin Muscarinic acetylcholine receptor M2 0 Activities
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ACHE Tclin Acetylcholinesterase 0 Activities
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CHRM1 Tclin Muscarinic acetylcholine receptor M1 0 Activities
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ADRA2A Tclin Alpha-2A adrenergic receptor 0 Activities
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ADRA1A Tclin Alpha-1A adrenergic receptor 0 Activities
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AR Tclin Androgen receptor 0 Activities
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MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities
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HTR1A Tclin 5-hydroxytryptamine receptor 1A 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ADORA3 Tchem Adenosine receptor A3 0 Activities
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HTR2B Tclin 5-hydroxytryptamine receptor 2B 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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TBXA2R Tclin Thromboxane A2 receptor 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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F2 Tclin Prothrombin 0 Activities
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KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities
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OPRM1 Tclin Mu-type opioid receptor 0 Activities
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Names and Identifiers
| IUPAC Name | (2S,3R)-2-amino-3-hydroxybutanoic acid |
|---|---|
| INCHI | InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1 |
| InChi Key | AYFVYJQAPQTCCC-GBXIJSLDSA-N |
| Canonical SMILES | CC(C(C(=O)O)N)O |
| Isomeric SMILES | C[C@H]([C@@H](C(=O)O)N)O |
| RTECS | XO8590000 |
| PubChem CID | 6288 |
| Molecular Weight | 119.13 |
| Beilstein | 1721646 |
| Reaxy-Rn | 1721646 |
Certificates
Certificate of Analysis(COA)
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Chemical and Physical Properties
| Specific Rotation[α] | -28 ° (C=6, H2O) |
|---|---|
| Melt Point(°C) | 256 °C (dec.) (lit.) |
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
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| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| RTECS | XO8590000 |
| Reaxy-Rn | 1721646 |
| Merck Index | 9380 |