L-Thyroxine - 10mM in DMSO, high purity , CAS No.51-48-9(DMSO)

Item Number

L408317

Grouped product items
SKU	Size	Availability	Price	Qty
L408317-1ml	1ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$205.90

Basic Description

Specifications & Purity	Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms	L-Thyroxine (NSC 36397) is a synthetic form of thyroxine and a hormone replacement drug.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Product Description	Information L-Thyroxine (NSC 36397) is a synthetic form of thyroxine and a hormone replacement drug. In vitro In vivo Cell Data cell lines： Concentrations： Incubation Time： Powder Purity:≥97%

Associated Targets(Human)

THRA Tclin Thyroid hormone receptor alpha (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

THRB Tclin Thyroid hormone receptor beta (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Canonical SMILES

NC(CC1=CC(=C(OC2=CC(=C(O)C(=C2)I)I)C(=C1)I)I)C(O)=O

Molecular Weight

776.87

Citations of This Product

1. Xinyi Li, Kaiyue Li, Jiayi Li, Zhiqin Zhang, Hongyuan Wang. (2023) Effects of perchlorate and exogenous T4 on growth, development and tail resorption of Rana chensinensis. ENVIRONMENTAL POLLUTION, [PMID:37558196]
2. Yangyang Wang, Yanping Sun, Bingyou Yang, Qiuhong Wang, Haixue Kuang. (2023) Integrate metabolomics strategy and target prediction to reveal the ameliorate effect of four typical ‘cold’ property herbs on hyperthyroidism rats. JOURNAL OF ETHNOPHARMACOLOGY, 301 (115772). [PMID:36202164]
3. Wang Yang-Yang, Sun Yan-Ping, Yang Bing-You, Wang Qiu-Hong, Kuang Hai-Xue. (2022) Application of metabolomics and network analysis to reveal the ameliorating effect of four typical “hot” property herbs on hypothyroidism rats. Frontiers in Pharmacology, 13 [PMID:36091783]
4. Quan Chi, Wenxiang Zhang, Lang Wang, Juan Huang, Ming Yuan, Huaming Xiao, Xian Wang. (2020) Evaluation of structurally different brominated flame retardants interacting with the transthyretin and their toxicity on HepG2 cells. CHEMOSPHERE, 246 (125749). [PMID:31927367]
5. Mei Yang, Youning Ma, Wenjun Gui, Yiping Ren, Guonian Zhu, Yihua Liu. (2015) Determination of 26 endocrine disrupting chemicals in fish and water using modified QuEChERS combined with solid-phase extraction and UHPLC-MS/MS. Analytical Methods, 7 (19): (8418-8431). [PMID:]

References

1. Xinyi Li, Kaiyue Li, Jiayi Li, Zhiqin Zhang, Hongyuan Wang. (2023) Effects of perchlorate and exogenous T4 on growth, development and tail resorption of Rana chensinensis. ENVIRONMENTAL POLLUTION, [PMID:37558196]
2. Yangyang Wang, Yanping Sun, Bingyou Yang, Qiuhong Wang, Haixue Kuang. (2023) Integrate metabolomics strategy and target prediction to reveal the ameliorate effect of four typical ‘cold’ property herbs on hyperthyroidism rats. JOURNAL OF ETHNOPHARMACOLOGY, 301 (115772). [PMID:36202164]
3. Wang Yang-Yang, Sun Yan-Ping, Yang Bing-You, Wang Qiu-Hong, Kuang Hai-Xue. (2022) Application of metabolomics and network analysis to reveal the ameliorating effect of four typical “hot” property herbs on hypothyroidism rats. Frontiers in Pharmacology, 13 [PMID:36091783]
4. Quan Chi, Wenxiang Zhang, Lang Wang, Juan Huang, Ming Yuan, Huaming Xiao, Xian Wang. (2020) Evaluation of structurally different brominated flame retardants interacting with the transthyretin and their toxicity on HepG2 cells. CHEMOSPHERE, 246 (125749). [PMID:31927367]
5. Mei Yang, Youning Ma, Wenjun Gui, Yiping Ren, Guonian Zhu, Yihua Liu. (2015) Determination of 26 endocrine disrupting chemicals in fish and water using modified QuEChERS combined with solid-phase extraction and UHPLC-MS/MS. Analytical Methods, 7 (19): (8418-8431). [PMID:]

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Basic Description