L-Thyroxine - 98%, high purity , CAS No.51-48-9, Agonist of Thyroid hormone receptor-α;Agonist of Thyroid hormone receptor-β

Item Number

T106193

• Synonyms: T4 | DivK1c_006967 | L-Thyroxine, free acid | Spectrum_001076 | 2ceo | Eutirox | L Thyroxine | LEVOTHYROXINE (USP-RS) | Prestwick_548 | 1hk4 | beta-((3,5-Diiodo-4-hydroxyphenoxy)-3,5-diiodophenyl)alanine | MLS002548901 | O-(4-Hydroxy-3,5-diiodophenyl)-3,5
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: an iodine containing hormone produced from thyroglobulin in the thyroid follicular cells. L-Thyroxine reduces total cholesterol level, low-density lipoprotein cholesterol as well as waist to hip ratio in subclinical hypothyroidism pateints.Synthetic T4 th
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: AGONIST
• Mechanism of action: Agonist of Thyroid hormone receptor-α;Agonist of Thyroid hormone receptor-β
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. L-Thyroxine (NSC 36397) is released from thyroglobulin by proteolysis and secreted into the blood. L-Thyroxine (NSC 36397) is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.