Click Here for 5% Off Your First Aladdin Purchase!

L-Tryptophan - 99%, high purity , CAS No.73-22-3

  • Moligand™
  • ≥99%
Item Number
T103480
Grouped product items
SKUSizeAvailabilityPrice Qty
T103480-25g
25g
In stock
$27.90
T103480-100g
100g
In stock
$78.90
T103480-500g
500g
In stock
$354.90

Essential amino acid.

Basic Description

SynonymsL-tryptophan|tryptophan|73-22-3|L-Tryptophane|h-Trp-oh|(S)-Tryptophan|Tryptophane|trofan|tryptacin|Ardeytropin|Optimax|Pacitron|(2S)-2-amino-3-(1H-indol-3-yl)propanoic acid|Indole-3-alanine|Kalma|L-beta-3-Indolylalanine|L-Tryptofan|L-Trp|L-(-)-Tryptophan|
Specifications & PurityMoligand™, ≥99%
Biochemical and Physiological MechanismsEssential amino acid which is necessary for normal growth in infants and for nitrogen balance in adults. Used as an antidepressant, anxiolytic and sleep aid. Precursor to niacin, indole alkaloids, serotonin and melatonin.
Shipped InNormal
GradeMoligand™
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets

CTH Tchem Cystathionine gamma-lyase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2D6 Tclin Cytochrome P450 2D6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2C19 Tchem Cytochrome P450 2C19 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DNMT1 Tclin DNA (cytosine-5)-methyltransferase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GPR17 Tchem Uracil nucleotide/cysteinyl leukotriene receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DHFR Tclin Dihydrofolate reductase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA5A Tclin Carbonic anhydrase 5A, mitochondrial 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2C9 Tchem Cytochrome P450 2C9 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC36A1 Tchem Proton-coupled amino acid transporter 1 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HIF1A Tchem Hypoxia-inducible factor 1-alpha 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KMT2A Tchem Histone-lysine N-methyltransferase 2A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

FEN1 Tchem Flap endonuclease 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KYAT1 Tbio Kynurenine--oxoglutarate transaminase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TXNRD1 Tclin Thioredoxin reductase 1, cytoplasmic 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TSHR Tclin Thyrotropin receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PLAA Tchem Phospholipase A-2-activating protein 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

POLI Tchem DNA polymerase iota 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MPO Tchem Myeloperoxidase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PKM Tchem Pyruvate kinase PKM 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

LDHB Tchem L-lactate dehydrogenase B chain 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC7A5 Tchem Large neutral amino acids transporter small subunit 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABCC2 Tchem Canalicular multispecific organic anion transporter 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA5B Tclin Carbonic anhydrase 5B, mitochondrial 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA6 Tclin Carbonic anhydrase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA13 Tclin Carbonic anhydrase 13 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA1 Tclin Carbonic anhydrase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA3 Tclin Carbonic anhydrase 3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA2 Tclin Carbonic anhydrase 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA4 Tclin Carbonic anhydrase 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA12 Tclin Carbonic anhydrase 12 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA14 Tclin Carbonic anhydrase 14 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA9 Tclin Carbonic anhydrase 9 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA7 Tclin Carbonic anhydrase 7 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC1A5 Tchem Neutral amino acid transporter B(0) 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ALB Tchem Serum albumin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TDO2 Tchem Tryptophan 2,3-dioxygenase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAPT Tclin Microtubule-associated protein tau 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GPR139 Tchem Probable G-protein coupled receptor 139 3 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ALPL Tchem Alkaline phosphatase, tissue-nonspecific isozyme 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

IDO1 Tchem Indoleamine 2,3-dioxygenase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KDM4E Tchem Lysine-specific demethylase 4E 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MMP3 Tchem Stromelysin-1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488180046
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180046
IUPAC Name (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid
INCHI InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1
InChi Key QIVBCDIJIAJPQS-VIFPVBQESA-N
Canonical SMILES C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N
Isomeric SMILES C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)O)N
PubChem CID 6305
Molecular Weight 204.23
Beilstein 86197

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

28 results found

Lot NumberCertificate TypeDateItem
G2431501Certificate of AnalysisAug 02, 2024 T103480
G2431500Certificate of AnalysisAug 02, 2024 T103480
G2431494Certificate of AnalysisAug 02, 2024 T103480
G2431492Certificate of AnalysisAug 02, 2024 T103480
G2431525Certificate of AnalysisAug 02, 2024 T103480
C2421743Certificate of AnalysisMar 01, 2024 T103480
C2421754Certificate of AnalysisMar 01, 2024 T103480
I2205128Certificate of AnalysisMay 24, 2023 T103480
C23071114Certificate of AnalysisMar 10, 2023 T103480
C23071117Certificate of AnalysisMar 10, 2023 T103480
C23071110Certificate of AnalysisMar 09, 2023 T103480
C23071193Certificate of AnalysisMar 09, 2023 T103480
C23071144Certificate of AnalysisMar 09, 2023 T103480
I2205321Certificate of AnalysisSep 09, 2022 T103480
I2205126Certificate of AnalysisSep 09, 2022 T103480
I2205125Certificate of AnalysisSep 09, 2022 T103480
I2205123Certificate of AnalysisSep 09, 2022 T103480
J2318804Certificate of AnalysisSep 09, 2022 T103480
B2318514Certificate of AnalysisSep 09, 2022 T103480
L2308051Certificate of AnalysisMay 26, 2022 T103480
E2421072Certificate of AnalysisMay 26, 2022 T103480
E2224230Certificate of AnalysisMay 26, 2022 T103480
E2224096Certificate of AnalysisMay 26, 2022 T103480
E2224095Certificate of AnalysisMay 26, 2022 T103480
E2224093Certificate of AnalysisMay 26, 2022 T103480
E2224090Certificate of AnalysisMay 26, 2022 T103480
D2410026Certificate of AnalysisMay 26, 2022 T103480
D2312230Certificate of AnalysisMay 26, 2022 T103480

more

Chemical and Physical Properties

SolubilitySlightly soluble in water; Degree of Solubility in water: 11.4 g/l 25 °C; Slightly soluble in Ethanol; Very slightly soluble in Alcohol; Insoluble in Chloroform,Ether
Specific Rotation[α]-30.5 to -32.5 deg(C=1, H2O)
Melt Point(°C)277°C

Safety and Hazards(GHS)

Merck Index 9797

Related Documents

References

1. Garcia JM, Swerdloff R, Wang C, Kyle M, Kipnes M, Biller BM, Cook D, Yuen KC, Bonert V, Dobs A et al..  (2013)  Macimorelin (AEZS-130)-stimulated growth hormone (GH) test: validation of a novel oral stimulation test for the diagnosis of adult GH deficiency..  J Clin Endocrinol Metab,  98  (6): (2422-9).  [PMID:23559086]
2. Schinner C et al..  (2019)  Regulation of cardiac myocyte cohesion and gap junctions via desmosomal adhesion..  Acta Physiol (Oxf),  226  (2): (e13242).  [PMID:30582290]
3. E M Sternberg.  (1996-01-01)  Pathogenesis of L-tryptophan eosinophilia myalgia syndrome..  Advances in experimental medicine and biology,  398  (325-330).  [PMID:8906284]
4. D Riemann,U Vorderholzer.  (1999-01-09)  [Treatment of depression and sleep disorders. Significance of serotonin and L-tryptophan in pathophysiology and therapy]..  Fortschritte der Medizin,  116  ((32)): (40-42).  [PMID:9880951]
5. D C Chugani,O Muzik.  (2000-01-05)  Alpha[C-11]methyl-L-tryptophan PET maps brain serotonin synthesis and kynurenine pathway metabolism..  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism,  20  ((1)): (2-9).  [PMID:10616786]
6. Richard J Brennan,Robert H Schiestl.  (2004-02-11)  Detecting carcinogens with the yeast DEL assay..  Methods in molecular biology (Clifton, N.J.),  262  (111-124).  [PMID:14769958]
7. Yesu T Das,Manashi Bagchi,Debasis Bagchi,Harry G Preuss.  (2004-04-08)  Safety of 5-hydroxy-L-tryptophan..  Toxicology letters,  150  ((1)): (111-122).  [PMID:15068828]
8. A Grimmett,M N Sillence.  (2005-07-05)  Calmatives for the excitable horse: a review of L-tryptophan..  Veterinary journal (London, England : 1997),  170  ((1)): (24-32).  [PMID:15993787]
9. Osamu Takikawa.  (2005-09-24)  Biochemical and medical aspects of the indoleamine 2,3-dioxygenase-initiated L-tryptophan metabolism..  Biochemical and biophysical research communications,  338  ((1)): (12-19).  [PMID:16176799]
10. Phedias Diamandis,Jan Wildenhain,Ian D Clarke,Adrian G Sacher,Jeremy Graham,David S Bellows,Erick K M Ling,Ryan J Ward,Leanne G Jamieson,Mike Tyers,Peter B Dirks.  (2007-04-10)  Chemical genetics reveals a complex functional ground state of neural stem cells..  Nature chemical biology,  ((5)): (268-273).  [PMID:17417631]
11. Daniela Vullo,Alessio Innocenti,Isao Nishimori,Andrea Scozzafava,Kai Kaila,Claudiu T Supuran.  (2007-06-02)  Carbonic anhydrase activators: activation of the human isoforms VII (cytosolic) and XIV (transmembrane) with amino acids and amines..  Bioorganic & medicinal chemistry letters,  17  ((15)): (4107-4112).  [PMID:17540561]
12. M Majewska,K Zajac,M Zemelka,M Szczepanik.  (2008-03-28)  Influence of melatonin and its precursor L-tryptophan on Th1 dependent contact hypersensitivity..  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society,  58 Suppl 6  (125-132).  [PMID:18212406]
13. Suneela S Dhaneshwar,Mukta Chail,Mahavir Patil,Salma Naqvi,Gaurav Vadnerkar.  (2008-05-13)  Colon-specific mutual amide prodrugs of 4-aminosalicylic acid for their mitigating effect on experimental colitis in rats..  European journal of medicinal chemistry,  44  ((1)): (131-142).  [PMID:18472188]
14. Claudia Temperini,Alessio Innocenti,Andrea Scozzafava,Claudiu T Supuran.  (2008-09-09)  Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV..  Bioorganic & medicinal chemistry,  16  ((18)): (8373-8378).  [PMID:18774300]
15. Alessio Innocenti,Sabrina A Zimmerman,Andrea Scozzafava,James G Ferry,Claudiu T Supuran.  (2008-10-22)  Carbonic anhydrase activators: activation of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases with amino acids and amines..  Bioorganic & medicinal chemistry letters,  18  ((23)): (6194-6198).  [PMID:18930395]
16. Huixi Zou,Xiaodong Zheng,Shu-Ming Li.  (2008-12-31)  Substrate promiscuity of the cyclic dipeptide prenyltransferases from Aspergillus fumigatus ( section sign)..  Journal of natural products,  72  ((1)): (44-52).  [PMID:19113967]
17. Semra Isik,Feray Kockar,Meltem Aydin,Oktay Arslan,Ozen Ozensoy Guler,Alessio Innocenti,Andrea Scozzafava,Claudiu T Supuran.  (2009-02-24)  Carbonic anhydrase activators: activation of the beta-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids..  Bioorganic & medicinal chemistry letters,  19  ((6)): (1662-1665).  [PMID:19231177]
18. Qian Han,Howard Robinson,Tao Cai,Danilo A Tagle,Jianyong Li.  (2009-04-03)  Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K..  Journal of medicinal chemistry,  52  ((9)): (2786-2793).  [PMID:19338303]
19. Suneela S Dhaneshwar,Neha Gairola,Mini Kandpal,Gaurav Vadnerkar,Lokesh Bhatt,Badal Rathi,S S Kadam.  (2009-05-16)  Synthesis, kinetic studies and pharmacological evaluation of mutual azo prodrugs of 5-aminosalicylic acid for colon-specific drug delivery in inflammatory bowel disease..  European journal of medicinal chemistry,  44  ((10)): (3922-3929).  [PMID:19442419]
20. Alessio Innocenti,Mika Hilvo,Seppo Parkkila,Andrea Scozzafava,Claudiu T Supuran.  (2009-05-26)  Carbonic anhydrase activators. Activation of the membrane-associated isoform XV with amino acids and amines..  Bioorganic & medicinal chemistry letters,  19  ((13)): (3430-3433).  [PMID:19464888]
21. Jing Yuan,Ronald L Johnson,Ruili Huang,Jennifer Wichterman,Hongying Jiang,Karen Hayton,David A Fidock,Thomas E Wellems,James Inglese,Christopher P Austin,Xin-zhuan Su.  (2009-09-08)  Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum..  Nature chemical biology,  ((10)): (765-771).  [PMID:19734910]
22. Marion Lanier,Eduard Sergienko,Ana Maria Simão,Ying Su,Thomas Chung,José Luis Millán,John R Cashman.  (2009-12-25)  Design and synthesis of selective inhibitors of placental alkaline phosphatase..  Bioorganic & medicinal chemistry,  18  ((2)): (573-579).  [PMID:20031422]
23. Alessio Innocenti,Rebecca A Hall,Andrea Scozzafava,Fritz A Mühlschlegel,Claudiu T Supuran.  (2010-01-12)  Carbonic anhydrase activators: activation of the beta-carbonic anhydrases from the pathogenic fungi Candida albicans and Cryptococcus neoformans with amines and amino acids..  Bioorganic & medicinal chemistry,  18  ((3)): (1034-1037).  [PMID:20061162]
24. Anthony Bertucci,Didier Zoccola,Sylvie Tambutté,Daniela Vullo,Claudiu T Supuran.  (2010-02-24)  Carbonic anhydrase activators. The first activation study of a coral secretory isoform with amino acids and amines..  Bioorganic & medicinal chemistry,  18  ((6)): (2300-2303).  [PMID:20176489]
25. Mónica S Estevão,Luísa C Carvalho,Daniela Ribeiro,Diana Couto,Marisa Freitas,Ana Gomes,L M Ferreira,Eduarda Fernandes,M Manuel B Marques.  (2010-08-24)  Antioxidant activity of unexplored indole derivatives: synthesis and screening..  European journal of medicinal chemistry,  45  ((11)): (4869-4878).  [PMID:20727623]
26. Rafat M Mohareb,Hanaa H Ahmed,Gamal A Elmegeed,Mervat M Abd-Elhalim,Reham W Shafic.  (2011-04-16)  Development of new indole-derived neuroprotective agents..  Bioorganic & medicinal chemistry,  19  ((9)): (2966-2974).  [PMID:21493072]
27. Diane C Chugani.  (2011-10-19)  α-methyl-L-tryptophan: mechanisms for tracer localization of epileptogenic brain regions..  Biomarkers in medicine,  ((5)): (567-575).  [PMID:22003905]
28. Nina Piggott,Michael A Cook,Mike Tyers,Vivien Measday.  (2012-03-03)  Genome-wide Fitness Profiles Reveal a Requirement for Autophagy During Yeast Fermentation..  G3 (Bethesda, Md.),  ((5)): (353-367).  [PMID:22384346]
29. George Anderson,Michael Maes.  (2012-07-18)  Schizophrenia: linking prenatal infection to cytokines, the tryptophan catabolite (TRYCAT) pathway, NMDA receptor hypofunction, neurodevelopment and neuroprogression..  Progress in neuro-psychopharmacology & biological psychiatry,  42  (5-19).  [PMID:22800757]
30. Michael Platten,Wolfgang Wick,Benoît J Van den Eynde.  (2012-10-24)  Tryptophan catabolism in cancer: beyond IDO and tryptophan depletion..  Cancer research,  72  ((21)): (5435-5440).  [PMID:23090118]
31. Gokce Nardemir,Derya Yanmis,Lokman Alpsoy,Medine Gulluce,Guleray Agar,Ali Aslan.  (2013-03-05)  Genotoxic, antigenotoxic and antioxidant properties of methanol extracts obtained from Peltigera horizontalis and Peltigera praetextata..  Toxicology and industrial health,  31  ((7)): (602-613).  [PMID:23456815]
32. Annemieke T van der Goot,Ellen A A Nollen.  (2013-04-09)  Tryptophan metabolism: entering the field of aging and age-related pathologies..  Trends in molecular medicine,  19  ((6)): (336-344).  [PMID:23562344]
33. Geoffrey L Stephens,Qun Wang,Bonnie Swerdlow,Geetha Bhat,Roland Kolbeck,Michael Fung.  (2013-04-10)  Kynurenine 3-monooxygenase mediates inhibition of Th17 differentiation via catabolism of endogenous aryl hydrocarbon receptor ligands..  European journal of immunology,  43  ((7)): (1727-1734).  [PMID:23568529]
34. Gergely N Nagy,Lívia Marton,Balázs Krámos,Julianna Oláh,Ágnes Révész,Károly Vékey,Frédéric Delsuc,Éva Hunyadi-Gulyás,Katalin F Medzihradszky,Marina Lavigne,Henri Vial,Rachel Cerdan,Beáta G Vértessy.  (2013-04-13)  Evolutionary and mechanistic insights into substrate and product accommodation of CTP:phosphocholine cytidylyltransferase from Plasmodium falciparum..  The FEBS journal,  280  ((13)): (3132-3148).  [PMID:23578277]
35. Julie M Fox,Leo K Sage,Lei Huang,James Barber,Kimberly D Klonowski,Andrew L Mellor,S Mark Tompkins,Ralph A Tripp.  (2013-04-13)  Inhibition of indoleamine 2,3-dioxygenase enhances the T-cell response to influenza virus infection..  The Journal of general virology,  94  ((Pt 7)): (1451-1461).  [PMID:23580425]
36. D Theofylaktopoulou,Ø Midttun,A Ulvik,P M Ueland,G S Tell,S E Vollset,O Nygård,S J P M Eussen.  (2013-04-24)  A community-based study on determinants of circulating markers of cellular immune activation and kynurenines: the Hordaland Health Study..  Clinical and experimental immunology,  173  ((1)): (121-130).  [PMID:23607723]
37. Simone C Wiesler,Robert O J Weinzierl,Martin Buck.  (2013-04-24)  An aromatic residue switch in enhancer-dependent bacterial RNA polymerase controls transcription intermediate complex activity..  Nucleic acids research,  41  ((11)): (5874-5886).  [PMID:23609536]
38. Kei Hiruma,Satoshi Fukunaga,Pawel Bednarek,Mariola Pislewska-Bednarek,Satoshi Watanabe,Yoshihiro Narusaka,Ken Shirasu,Yoshitaka Takano.  (2013-05-23)  Glutathione and tryptophan metabolism are required for Arabidopsis immunity during the hypersensitive response to hemibiotrophs..  Proceedings of the National Academy of Sciences of the United States of America,  110  ((23)): (9589-9594).  [PMID:23696664]
39. Tobias W Giessen,Alexander M von Tesmar,Mohamed A Marahiel.  (2013-05-28)  A tRNA-dependent two-enzyme pathway for the generation of singly and doubly methylated ditryptophan 2,5-diketopiperazines..  Biochemistry,  52  ((24)): (4274-4283).  [PMID:23705796]
40. Victor L Davidson,Carrie M Wilmot.  (2013-06-12)  Posttranslational biosynthesis of the protein-derived cofactor tryptophan tryptophylquinone..  Annual review of biochemistry,  82  (531-550).  [PMID:23746262]
41. Gregory Oxenkrug.  (2013-07-03)  Insulin resistance and dysregulation of tryptophan-kynurenine and kynurenine-nicotinamide adenine dinucleotide metabolic pathways..  Molecular neurobiology,  48  ((2)): (294-301).  [PMID:23813101]
42. Sooim Shin,Manliang Feng,Victor L Davidson.  (2013-09-13)  Mutation of Trp(93) of MauG to tyrosine causes loss of bound Ca(2+) and alters the kinetic mechanism of tryptophan tryptophylquinone cofactor biosynthesis..  The Biochemical journal,  456  ((1)): (129-137).  [PMID:24024544]
43. Wendy Niedelman,Joris K Sprokholt,Barbara Clough,Eva-Maria Frickel,Jeroen P J Saeij.  (2013-09-18)  Cell death of gamma interferon-stimulated human fibroblasts upon Toxoplasma gondii infection induces early parasite egress and limits parasite replication..  Infection and immunity,  81  ((12)): (4341-4349).  [PMID:24042117]
44. Kathleen M Meneely,Qianyi Luo,Audrey L Lamb.  (2013-09-24)  Redesign of MST enzymes to target lyase activity instead promotes mutase and dehydratase activities..  Archives of biochemistry and biophysics,  539  ((1)): (70-80).  [PMID:24055536]
45. Flaviano Giorgini,Shao-Yi Huang,Korrapati V Sathyasaikumar,Francesca M Notarangelo,Marian A R Thomas,Margarita Tararina,Hui-Qiu Wu,Robert Schwarcz,Paul J Muchowski.  (2013-11-06)  Targeted deletion of kynurenine 3-monooxygenase in mice: a new tool for studying kynurenine pathway metabolism in periphery and brain..  The Journal of biological chemistry,  288  ((51)): (36554-36566).  [PMID:24189070]
46. Timothy H Yosca,Jonathan Rittle,Courtney M Krest,Elizabeth L Onderko,Alexey Silakov,Julio C Calixto,Rachel K Behan,Michael T Green.  (2013-11-16)  Iron(IV)hydroxide pK(a) and the role of thiolate ligation in C-H bond activation by cytochrome P450..  Science (New York, N.Y.),  342  ((6160)): (825-829).  [PMID:24233717]
47. Narendra Nath Jha,A Anoop,Srivastav Ranganathan,Ganesh M Mohite,Ranjith Padinhateeri,Samir K Maji.  (2013-11-19)  Characterization of amyloid formation by glucagon-like peptides: role of basic residues in heparin-mediated aggregation..  Biochemistry,  52  ((49)): (8800-8810).  [PMID:24236650]
48. Ting-Fang He,Lijun Guo,Xunmin Guo,Chih-Wei Chang,Lijuan Wang,Dongping Zhong.  (2013-12-03)  Femtosecond dynamics of short-range protein electron transfer in flavodoxin..  Biochemistry,  52  ((51)): (9120-9128).  [PMID:24289221]
49. Jiafeng Geng,Aimin Liu.  (2013-12-04)  Heme-dependent dioxygenases in tryptophan oxidation..  Archives of biochemistry and biophysics,  544  (18-26).  [PMID:24295960]
50. Vera Alverdi,Byron Hetrick,Simpson Joseph,Elizabeth A Komives.  (2013-12-25)  Direct observation of a transient ternary complex during IκBα-mediated dissociation of NF-κB from DNA..  Proceedings of the National Academy of Sciences of the United States of America,  111  ((1)): (225-230).  [PMID:24367071]
51. Lissandra Castellan Baldan,Kyle A Williams,Jean-Dominique Gallezot,Vladimir Pogorelov,Maximiliano Rapanelli,Michael Crowley,George M Anderson,Erin Loring,Roxanne Gorczyca,Eileen Billingslea,Suzanne Wasylink,Kaitlyn E Panza,A Gulhan Ercan-Sencicek,Kuakarun Krusong,Bennett L Leventhal,Hiroshi Ohtsu,Michael H Bloch,Zoë A Hughes,John H Krystal,Linda Mayes,Ivan de Araujo,Yu-Shin Ding,Matthew W State,Christopher Pittenger.  (2014-01-15)  Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice..  Neuron,  81  ((1)): (77-90).  [PMID:24411733]
52. Ingvar J Rognum,Hoa Tran,Elisabeth A Haas,Keith Hyland,David S Paterson,Robin L Haynes,Kevin G Broadbelt,Brian J Harty,Othon Mena,Henry F Krous,Hannah C Kinney.  (2014-01-16)  Serotonin metabolites in the cerebrospinal fluid in sudden infant death syndrome..  Journal of neuropathology and experimental neurology,  73  ((2)): (115-122).  [PMID:24423636]
53. Marco Pistolozzi,Cecilia Fortugno,Carlo Franchini,Filomena Corbo,Marilena Muraglia,Myriam Roy,Guy Félix,Carlo Bertucci.  (2014-01-30)  Species-dependent binding of tocainide analogues to albumin: affinity chromatography and circular dichroism study..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  968  (69-78).  [PMID:24472243]
54. E M Apalset,C G Gjesdal,P M Ueland,Ø Midttun,A Ulvik,G E Eide,K Meyer,G S Tell.  (2014-02-18)  Interferon (IFN)-γ-mediated inflammation and the kynurenine pathway in relation to bone mineral density: the Hordaland Health Study..  Clinical and experimental immunology,  176  ((3)): (452-460).  [PMID:24528145]
55. Asta Rós Sigtryggsdóttir,Elena Papaleo,Sigríður H Thorbjarnardóttir,Magnús M Kristjánsson.  (2014-02-25)  Flexibility of cold- and heat-adapted subtilisin-like serine proteinases evaluated with fluorescence quenching and molecular dynamics..  Biochimica et biophysica acta,  1844  ((4)): (705-712).  [PMID:24561657]
56. Bogumil Zelent,Anne Raimondo,Amy Barrett,Carol W Buettger,Pan Chen,Anna L Gloyn,Franz M Matschinsky.  (2014-02-27)  Analysis of the co-operative interaction between the allosterically regulated proteins GK and GKRP using tryptophan fluorescence..  The Biochemical journal,  459  ((3)): (551-564).  [PMID:24568320]
57. Alexander A Voityuk,Rudolph A Marcus,Maria-Elisabeth Michel-Beyerle.  (2014-03-19)  On the mechanism of photoinduced dimer dissociation in the plant UVR8 photoreceptor..  Proceedings of the National Academy of Sciences of the United States of America,  111  ((14)): (5219-5224).  [PMID:24639509]
58. Felipe Montecinos-Franjola,Nicholas G James,Luis Concha-Marambio,Juan E Brunet,Rosalba Lagos,Octavio Monasterio,David M Jameson.  (2014-04-08)  Single tryptophan mutants of FtsZ: nucleotide binding/exchange and conformational transitions..  Biochimica et biophysica acta,  1844  ((7)): (1193-1200).  [PMID:24704635]
59. Yvonne Ritze,Gyöngyi Bárdos,Astrid Hubert,Maureen Böhle,Stephan C Bischoff.  (2014-04-09)  Effect of tryptophan supplementation on diet-induced non-alcoholic fatty liver disease in mice..  The British journal of nutrition,  112  ((1)): (1-7).  [PMID:24708895]
60. Arunima Chaudhuri,Amitabha Chattopadhyay.  (2014-05-08)  Lipid binding specificity of bovine α-lactalbumin: a multidimensional approach..  Biochimica et biophysica acta,  1838  ((8)): (2078-2086).  [PMID:24802274]
61. Yuxin An,Qian Li,Jiejun Chen,Xiaokang Gao,Hongwei Chen,Chaoni Xiao,Liujiao Bian,Jianbin Zheng,Xinfeng Zhao,Xiaohui Zheng.  (2014-05-16)  Binding of caffeic acid to human serum albumin by the retention data and frontal analysis..  Biomedical chromatography : BMC,  28  ((12)): (1881-1886).  [PMID:24828401]
62. Sabrina Thomas,Patrick J Bakkes,Sander H J Smits,Lutz Schmitt.  (2014-05-29)  Equilibrium folding of pro-HlyA from Escherichia coli reveals a stable calcium ion dependent folding intermediate..  Biochimica et biophysica acta,  1844  ((9)): (1500-1510).  [PMID:24865936]
63. Nicole Seegers,Antoon M van Doornmalen,Joost C M Uitdehaag,Jos de Man,Rogier C Buijsman,Guido J R Zaman.  (2014-05-30)  High-throughput fluorescence-based screening assays for tryptophan-catabolizing enzymes..  Journal of biomolecular screening,  19  ((9)): (1266-1274).  [PMID:24870017]
64. Chaofu Ke,Yan Hou,Haiyu Zhang,Lijun Fan,Tingting Ge,Bing Guo,Fan Zhang,Kai Yang,Jingtao Wang,Ge Lou,Kang Li.  (2014-06-05)  Large-scale profiling of metabolic dysregulation in ovarian cancer..  International journal of cancer,  136  ((3)): (516-526).  [PMID:24895217]
65. Valentina Folgiero,Bianca M Goffredo,Perla Filippini,Riccardo Masetti,Giuseppina Bonanno,Roberta Caruso,Valentina Bertaina,Angela Mastronuzzi,Stefania Gaspari,Marco Zecca,Giovanni F Torelli,Anna M Testi,Andrea Pession,Franco Locatelli,Sergio Rutella.  (2014-06-07)  Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia..  Oncotarget,  ((8)): (2052-2064).  [PMID:24903009]
66. William W Parson.  (2014-06-28)  Competition between tryptophan fluorescence and electron transfer during unfolding of the villin headpiece..  Biochemistry,  53  ((28)): (4503-4509).  [PMID:24972184]
67. Dan Liu,Xiaowei Zou,Mingzhe Gao,Ming Gu,Hongbin Xiao.  (2014-07-08)  Hydrophilic organic/salt-containing aqueous two-phase solvent system for counter-current chromatography: a novel technique for separation of polar compounds..  Journal of chromatography. A,  1356  (157-162).  [PMID:24999067]
68. Linda Booij,Jean-Paul Soucy,Simon N Young,Martine Regoli,Paul Gravel,Mirko Diksic,Marco Leyton,Robert O Pihl,Chawki Benkelfat.  (2014-07-22)  Brain serotonin synthesis in MDMA (ecstasy) polydrug users: an alpha-[(11) C]methyl-l-tryptophan study..  Journal of neurochemistry,  131  ((5)): (634-644).  [PMID:25041501]
69. Minh Truong Do,Hyung Gyun Kim,Thi Thu Phuong Tran,Tilak Khanal,Jae Ho Choi,Young Chul Chung,Tae Cheon Jeong,Hye Gwang Jeong.  (2014-08-12)  Metformin suppresses CYP1A1 and CYP1B1 expression in breast cancer cells by down-regulating aryl hydrocarbon receptor expression..  Toxicology and applied pharmacology,  280  ((1)): (138-148).  [PMID:25110054]
70. Subha Karumuthil-Melethil,Radhika Gudi,Benjamin M Johnson,Nicolas Perez,Chenthamarakshan Vasu.  (2014-08-22)  Fungal β-glucan, a Dectin-1 ligand, promotes protection from type 1 diabetes by inducing regulatory innate immune response..  Journal of immunology (Baltimore, Md. : 1950),  193  ((7)): (3308-3321).  [PMID:25143443]
71. Elnaz Yaghini,Katharina F Pirker,Christopher W M Kay,Alexander M Seifalian,Alexander J MacRobert.  (2014-08-29)  Quantification of reactive oxygen species generation by photoexcitation of PEGylated quantum dots..  Small (Weinheim an der Bergstrasse, Germany),  10  ((24)): (5106-5115).  [PMID:25164061]
72. Ray Suhandynata,Jason Liang,Claudio P Albuquerque,Huilin Zhou,Nancy M Hollingsworth.  (2014-08-30)  A method for sporulating budding yeast cells that allows for unbiased identification of kinase substrates using stable isotope labeling by amino acids in cell culture..  G3 (Bethesda, Md.),  ((11)): (2125-2135).  [PMID:25168012]
73. Patrícia M Jorge,Iuri M de Oliveira,Eduardo C Filippi Chiela,Cassiana M Viau,Jenifer Saffi,Fabiana Horn,Renato M Rosa,Temenouga N Guecheva,João A Pêgas Henriques.  (2014-08-30)  Diphenyl ditelluride-induced cell cycle arrest and apoptosis: a relation with topoisomerase I inhibition..  Basic & clinical pharmacology & toxicology,  116  ((3)): (273-280).  [PMID:25168415]
74. Aneta Piesiewicz,Urszula Kedzierska,Elzbieta Turkowska,Iwona Adamska,Pawel M Majewski.  (2014-09-16)  Seasonal postembryonic maturation of the diurnal rhythm of serotonin in the chicken pineal gland..  Chronobiology international,  32  ((1)): (59-70).  [PMID:25222180]
75. Ramón Menta,Pablo Mancheño-Corvo,Borja Del Río,Cristina Ramírez,Olga DelaRosa,Wilfried Dalemans,Eleuterio Lombardo.  (2014-09-23)  Tryptophan concentration is the main mediator of the capacity of adipose mesenchymal stromal cells to inhibit T-lymphocyte proliferation in vitro..  Cytotherapy,  16  ((12)): (1679-1691).  [PMID:25239492]
76. Heidi Turkia,Heli Sirén,Merja Penttilä,Juha-Pekka Pitkänen.  (2014-10-05)  Capillary electrophoresis with laser-induced fluorescence detection for studying amino acid uptake by yeast during beer fermentation..  Talanta,  131  (366-371).  [PMID:25281116]
77. Laura E Rosen,Sagar V Kathuria,C Robert Matthews,Osman Bilsel,Susan Marqusee.  (2014-10-15)  Non-native structure appears in microseconds during the folding of E. coli RNase H..  Journal of molecular biology,  427  ((2)): (443-453).  [PMID:25311861]
78. Jian Jin,Haile Ma,Cunshan Zhou,Min Luo,Wan Liu,Wenjuan Qu,Ronghai He,Lin Luo,Abu El-Gasim A Yagoub.  (2014-11-05)  Effect of degree of hydrolysis on the bioavailability of corn gluten meal hydrolysates..  Journal of the science of food and agriculture,  95  ((12)): (2501-2509).  [PMID:25367020]
79. Hanne Sørup Tastesen,Alexander Krokedal Rønnevik,Kamil Borkowski,Lise Madsen,Karsten Kristiansen,Bjørn Liaset.  (2014-11-13)  A mixture of cod and scallop protein reduces adiposity and improves glucose tolerance in high-fat fed male C57BL/6J mice..  PloS one,  ((11)): (e112859-e112859).  [PMID:25390887]
80. Xiaoxia Zhu,Linlin Jing,Chun Chen,Meng Shao,Qin Fan,Jianxin Diao,Yuanliang Liu,Zhiping Lv,Xuegang Sun.  (2014-12-02)  Danzhi Xiaoyao San ameliorates depressive-like behavior by shifting toward serotonin via the downregulation of hippocampal indoleamine 2,3-dioxygenase..  Journal of ethnopharmacology,  160  (86-93).  [PMID:25435286]
81. Haneesha Mohan,Naresh Ramesh,Sima Mortazavi,Anthony Le,Hiroshi Iwakura,Suraj Unniappan.  (2014-12-17)  Nutrients differentially regulate nucleobindin-2/nesfatin-1 in vitro in cultured stomach ghrelinoma (MGN3-1) cells and in vivo in male mice..  PloS one,  ((12)): (e115102-e115102).  [PMID:25506938]
82. Meredith H Wilson,Erika L F Holzbaur.  (2014-12-18)  Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells..  Development (Cambridge, England),  142  ((1)): (218-228).  [PMID:25516977]
83. Luisa Rios-Avila,Bonnie Coats,Yueh-Yun Chi,Øivind Midttun,Per M Ueland,Peter W Stacpoole,Jesse F Gregory.  (2014-12-21)  Metabolite profile analysis reveals association of vitamin B-6 with metabolites related to one-carbon metabolism and tryptophan catabolism but not with biomarkers of inflammation in oral contraceptive users and reveals the effects of oral contraceptives on these processes..  The Journal of nutrition,  145  ((1)): (87-95).  [PMID:25527663]
84. Youzhong Guo,Ravi C Kalathur,Qun Liu,Brian Kloss,Renato Bruni,Christopher Ginter,Edda Kloppmann,Burkhard Rost,Wayne A Hendrickson.  (2015-01-31)  Protein structure. Structure and activity of tryptophan-rich TSPO proteins..  Science (New York, N.Y.),  347  ((6221)): (551-555).  [PMID:25635100]
85. Yasuo Ido,Albert Duranton,Fan Lan,Karen A Weikel,Lionel Breton,Neil B Ruderman.  (2015-02-04)  Resveratrol prevents oxidative stress-induced senescence and proliferative dysfunction by activating the AMPK-FOXO3 cascade in cultured primary human keratinocytes..  PloS one,  10  ((2)): (e0115341-e0115341).  [PMID:25647160]
86. Man Qiao,Chunyan Li,Ying Shi,Shaopu Liu,Zhongfang Liu,Xiaoli Hu.  (2015-03-05)  Study on interactions of aminoglycoside antibiotics with calf thymus DNA and determination of calf thymus DNA via the resonance Rayleigh scattering technique..  Luminescence : the journal of biological and chemical luminescence,  30  ((7)): (1159-1166).  [PMID:25736683]
87. Guang-Huey Lin,Chung-Yu Chang,Huei-Ru Lin.  (2015-03-10)  Systematic profiling of indole-3-acetic acid biosynthesis in bacteria using LC-MS/MS..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  988  (53-58).  [PMID:25746752]
88. Songyan Gao,Wei Chen,Zhongjiang Peng,Na Li,Li Su,Diya Lv,Ling Li,Qishan Lin,Xin Dong,Zhiyong Guo,Ziyang Lou.  (2015-03-22)  Urinary metabonomics elucidate the therapeutic mechanism of Orthosiphon stamineus in mouse crystal-induced kidney injury..  Journal of ethnopharmacology,  166  (323-332).  [PMID:25794803]
89. Lyudmila V Ignatova,Yelena V Brazhnikova,Ramza Z Berzhanova,Togzhan D Mukasheva.  (2015-04-07)  Plant growth-promoting and antifungal activity of yeasts from dark chestnut soil..  Microbiological research,  175  (78-83).  [PMID:25843007]
90. Ryan Matsuda,Zhao Li,Xiwei Zheng,David S Hage.  (2015-04-29)  Analysis of glipizide binding to normal and glycated human serum albumin by high-performance affinity chromatography..  Analytical and bioanalytical chemistry,  407  ((18)): (5309-5321).  [PMID:25912461]
91. Yung-Ping Lee,Tzong-Fu Kuo,Shoei-Sheng Lee.  (2015-05-02)  Identification of the metabolites of TCM prescription Sinisan, found in miniature pig urine via intragastric administration..  Journal of pharmaceutical and biomedical analysis,  111  (311-319).  [PMID:25931441]
92. Soranobu Ninomiya,Neeharika Narala,Leslie Huye,Shigeki Yagyu,Barbara Savoldo,Gianpietro Dotti,Helen E Heslop,Malcolm K Brenner,Cliona M Rooney,Carlos A Ramos.  (2015-05-06)  Tumor indoleamine 2,3-dioxygenase (IDO) inhibits CD19-CAR T cells and is downregulated by lymphodepleting drugs..  Blood,  125  ((25)): (3905-3916).  [PMID:25940712]
93. Josh P Clevenger,Jason Van Houten,Michelle Blackwood,Gustavo Rubén Rodríguez,Yusuke Jikumaru,Yuji Kamiya,Miyako Kusano,Kazuki Saito,Sofia Visa,Esther van der Knaap.  (2015-05-06)  Network Analyses Reveal Shifts in Transcript Profiles and Metabolites That Accompany the Expression of SUN and an Elongated Tomato Fruit..  Plant physiology,  168  ((3)): (1164-1178).  [PMID:25941316]
94. Cunshan Zhou,Jiali Hu,Haile Ma,Abu ElGasim A Yagoub,Xiaojie Yu,John Owusu,Haiyan Ma,Xiaopei Qin.  (2015-05-16)  Antioxidant peptides from corn gluten meal: Orthogonal design evaluation..  Food chemistry,  187  (270-278).  [PMID:25977026]
95. Tomohiro Shigemori,Kouichi Kuroda,Mitsuyoshi Ueda.  (2015-05-21)  Functional screening system for yeast-secreted peptides acting on G-protein coupled receptors..  AMB Express,  (26-26).  [PMID:25992304]
96. Fang Tao Xie,Ji Sen Cao,Jian Zhao,Yang Yu,Feng Qi,Xiang Chen Dai.  (2015-05-24)  IDO expressing dendritic cells suppress allograft rejection of small bowel transplantation in mice by expansion of Foxp3+ regulatory T cells..  Transplant immunology,  33  ((2)): (69-77).  [PMID:26002283]
97. Emilien Folzer,Katharina Diepold,Katrin Bomans,Christof Finkler,Roland Schmidt,Patrick Bulau,Jörg Huwyler,Hanns-Christian Mahler,Atanas V Koulov.  (2015-05-27)  Selective Oxidation of Methionine and Tryptophan Residues in a Therapeutic IgG1 Molecule..  Journal of pharmaceutical sciences,  104  ((9)): (2824-2831).  [PMID:26010344]
98. Mohammad Mahdi Moein,Mehran Javanbakht,Mohammad Karimi,Behrouz Akbari-Adergani,Mohamed Abdel-Rehim.  (2015-05-30)  Three-phase molecularly imprinted sol-gel based hollow fiber liquid-phase microextraction combined with liquid chromatography-tandem mass spectrometry for enrichment and selective determination of a tentative lung cancer biomarker..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  995-996  (38-45).  [PMID:26021850]
99. Tomohiro Shigemori,Kouichi Kuroda,Mitsuyoshi Ueda.  (2015-06-19)  Screening of randomly mutagenized glucagon-like peptide-1 library by using an integrated yeast-mammalian assay system..  Journal of biotechnology,  209  (96-101).  [PMID:26087314]
100. Zhi Chen,Wei Zhang,Liping Wang,Huajun Fan,Qiang Wan,Xuehao Wu,Xunyou Tang,James Z Tang.  (2015-07-17)  Enantioseparation of Racemic Flurbiprofen by Aqueous Two-Phase Extraction With Binary Chiral Selectors of L-dioctyl Tartrate and L-tryptophan..  Chirality,  27  ((9)): (650-657).  [PMID:26179618]
101. Yipin Wu,Michel Baum,Chou-Long Huang,Aylin R Rodan.  (2015-08-01)  Two inwardly rectifying potassium channels, Irk1 and Irk2, play redundant roles in Drosophila renal tubule function..  American journal of physiology. Regulatory, integrative and comparative physiology,  309  ((7)): (R747-R756).  [PMID:26224687]
102. Yakun Xie,Daniel Straub,Tenai Eguen,Ronny Brandt,Mark Stahl,Jaime F Martínez-García,Stephan Wenkel.  (2015-08-08)  Meta-Analysis of Arabidopsis KANADI1 Direct Target Genes Identifies a Basic Growth-Promoting Module Acting Upstream of Hormonal Signaling Pathways..  Plant physiology,  169  ((2)): (1240-1253).  [PMID:26246448]
103. Kazım Köse,Kadir Erol,Asiye Aslı Emniyet,Dursun Ali Köse,Gülçin Alp Avcı,Lokman Uzun.  (2015-08-13)  Fe(II)-Co(II) Double Salt Incorporated Magnetic Hydrophobic Microparticles for Invertase Adsorption..  Applied biochemistry and biotechnology,  177  ((5)): (1025-1039).  [PMID:26265396]
104. Monika Gibis,Jochen Weiss.  (2015-10-08)  Impact of Precursors Creatine, Creatinine, and Glucose on the Formation of Heterocyclic Aromatic Amines in Grilled Patties of Various Animal Species..  Journal of food science,  80  ((11)): (C2430-C2439).  [PMID:26445401]
105. Jiansheng Liu,Yajing He,Jun Zhang,Jiajia Li,Xiangrong Yu,Zhonglian Cao,Fanmin Meng,Yuwu Zhao,Xunyi Wu,Teng Shen,Zhen Hong.  (2015-10-09)  Functionalized nanocarrier combined seizure-specific vector with P-glycoprotein modulation property for antiepileptic drug delivery..  Biomaterials,  74  (64-76).  [PMID:26447556]
106. Verena Kriechbaumer.  (2017-02-10)  ER Microsome Preparation and Subsequent IAA Quantification in Maize Coleoptile and Primary Root Tissue..  Bio-protocol,  ((9)):   [PMID:28180138]
107. Jinrang Kim,Haruka Okamoto,ZhiJiang Huang,Guillermo Anguiano,Shiuhwei Chen,Qing Liu,Katie Cavino,Yurong Xin,Erqian Na,Rachid Hamid,Joseph Lee,Brian Zambrowicz,Roger Unger,Andrew J Murphy,Yan Xu,George D Yancopoulos,Wen-Hong Li,Jesper Gromada.  (2017-06-08)  Amino Acid Transporter Slc38a5 Controls Glucagon Receptor Inhibition-Induced Pancreatic α Cell Hyperplasia in Mice..  Cell metabolism,  25  ((6)): (1348-1361).  [PMID:28591637]
108. Yun Teng,Yi Ren,Mohammed Sayed,Xin Hu,Chao Lei,Anil Kumar,Elizabeth Hutchins,Jingyao Mu,Zhongbin Deng,Chao Luo,Kumaran Sundaram,Mukesh K Sriwastva,Lifeng Zhang,Michael Hsieh,Rebecca Reiman,Bodduluri Haribabu,Jun Yan,Venkatakrishna Rao Jala,Donald M Miller,Kendall Van Keuren-Jensen,Michael L Merchant,Craig J McClain,Juw Won Park,Nejat K Egilmez,Huang-Ge Zhang.  (2018-11-20)  Plant-Derived Exosomal MicroRNAs Shape the Gut Microbiota..  Cell host & microbe,  24  ((5)): (637-652).  [PMID:30449315]
109. Kevin M Cheung,Kyung-Ae Yang,Nako Nakatsuka,Chuanzhen Zhao,Mao Ye,Michael E Jung,Hongyan Yang,Paul S Weiss,Milan N Stojanović,Anne M Andrews.  (2019-10-22)  Phenylalanine Monitoring via Aptamer-Field-Effect Transistor Sensors..  ACS sensors,  ((12)): (3308-3317).  [PMID:31631652]
110. Chi-Hao Tsai,Ching-Hao Li,Po-Lin Liao,Yu-Wei Chang,Yu-Wen Cheng,Jaw-Jou Kang.  (2019-11-02)  Aza-PBHA, a potent histone deacetylase inhibitor, inhibits human gastric-cancer cell migration via PKCα-mediated AHR-HDAC interactions..  Biochimica et biophysica acta. Molecular cell research,  1867  ((2)): (118564-118564).  [PMID:31672612]
111. Morgan Robinson,Stephen Turnbull,Brenda Yasie Lee,Zoya Leonenko.  (2020-05-26)  The effects of melatonin, serotonin, tryptophan and NAS on the biophysical properties of DPPC monolayers..  Biochimica et biophysica acta. Biomembranes,  1862  ((9)): (183363-183363).  [PMID:32450141]
112. Miguel A Uc-Chuc,Cleyre Pérez-Hernández,Rosa M Galaz-Ávalos,Ligia Brito-Argaez,Víctor Aguilar-Hernández,Víctor M Loyola-Vargas.  (2020-07-09)  YUCCA-Mediated Biosynthesis of the Auxin IAA Is Required during the Somatic Embryogenic Induction Process in Coffea canephora..  International journal of molecular sciences,  21  ((13)):   [PMID:32635392]
113. Sébastien Coassolo,Guillaume Davidson,Luc Negroni,Giovanni Gambi,Sylvain Daujat,Christophe Romier,Irwin Davidson.  (2021-03-21)  Citrullination of pyruvate kinase M2 by PADI1 and PADI3 regulates glycolysis and cancer cell proliferation..  Nature communications,  12  ((1)): (1718-1718).  [PMID:33741961]
114. S R Daniels,J I Hudson,R I Horwitz.  (1995-12-01)  Epidemiology of potential association between L-tryptophan ingestion and eosinophilia-myalgia syndrome..  Journal of clinical epidemiology,  48  ((12)): (1413-1427).  [PMID:8543957]
115. D M Dougherty,F G Moeller,J M Bjork,D M Marsh.  (2000-03-18)  Plasma L-tryptophan depletion and aggression..  Advances in experimental medicine and biology,  467  (57-65).  [PMID:10721038]
116. Trevor W Stone,Nicholas Stoy,L Gail Darlington.  (2012-11-06)  An expanding range of targets for kynurenine metabolites of tryptophan..  Trends in pharmacological sciences,  34  ((2)): (136-143).  [PMID:23123095]
117. Yuki Murakami,Masato Hoshi,Yukio Imamura,Yuko Arioka,Yasuko Yamamoto,Kuniaki Saito.  (2013-03-12)  Remarkable role of indoleamine 2,3-dioxygenase and tryptophan metabolites in infectious diseases: potential role in macrophage-mediated inflammatory diseases..  Mediators of inflammation,  2013  (391984-391984).  [PMID:23476103]
118. Saara Ahmad,Saiqa Tabassum,Saida Haider.  (2013-07-20)  Role of decreased plasma tryptophan in memory deficits observed in type-I diabetes..  JPMA. The Journal of the Pakistan Medical Association,  63  ((1)): (65-68).  [PMID:23865134]
119. Sooim Shin,Victor L Davidson.  (2013-10-23)  MauG, a diheme enzyme that catalyzes tryptophan tryptophylquinone biosynthesis by remote catalysis..  Archives of biochemistry and biophysics,  544  (112-118).  [PMID:24144526]
120. Wilhelmina M Huston,Christopher J Barker,Anu Chacko,Peter Timms.  (2014-04-01)  Evolution to a chronic disease niche correlates with increased sensitivity to tryptophan availability for the obligate intracellular bacterium Chlamydia pneumoniae..  Journal of bacteriology,  196  ((11)): (1915-1924).  [PMID:24682324]
121. Gregory T Tietjen,Zhiliang Gong,Chiu-Hao Chen,Ernesto Vargas,James E Crooks,Kathleen D Cao,Charles T R Heffern,J Michael Henderson,Mati Meron,Binhua Lin,Benot Roux,Mark L Schlossman,Theodore L Steck,Ka Yee C Lee,Erin J Adams.  (2014-04-08)  Molecular mechanism for differential recognition of membrane phosphatidylserine by the immune regulatory receptor Tim4..  Proceedings of the National Academy of Sciences of the United States of America,  111  ((15)): (E1463-E1472).  [PMID:24706780]
122. M-A Jenabian,M Patel,I Kema,K Vyboh,C Kanagaratham,D Radzioch,P Thébault,R Lapointe,N Gilmore,P Ancuta,C Tremblay,J-P Routy.  (2014-06-14)  Soluble CD40-ligand (sCD40L, sCD154) plays an immunosuppressive role via regulatory T cell expansion in HIV infection..  Clinical and experimental immunology,  178  ((1)): (102-111).  [PMID:24924152]
123. Paul Cumming.  (2014-08-27)  Measuring effects of MDMA (ecstasy) abuse on the rate of cerebral serotonin synthesis..  Journal of neurochemistry,  131  ((5)): (541-545).  [PMID:25156194]
124. Oksana Zayachkivska,Olena Havryluk,Nazar Hrycevych,Nazar Bula,Oksana Grushka,John L Wallace.  (2014-10-22)  Cytoprotective effects of hydrogen sulfide in novel rat models of non-erosive esophagitis..  PloS one,  ((10)): (e110688-e110688).  [PMID:25333941]
125. Fumikazu Takahashi,Nobuyuki Sumitomo,Hiroshi Hagihara,Katsuya Ozaki.  (2014-11-18)  Increased dipicolinic acid production with an enhanced spoVF operon in Bacillus subtilis and medium optimization..  Bioscience, biotechnology, and biochemistry,  79  ((3)): (505-511).  [PMID:25402593]
126. Mohamed A Shehata,Anne C Nøhr,Delphine Lissa,Christoph Bisig,Vignir Isberg,Kirsten B Andersen,Kasper Harpsøe,Fredrik Björkling,Hans Bräuner-Osborne,David E Gloriam.  (2016-11-11)  Novel Agonist Bioisosteres and Common Structure-Activity Relationships for The Orphan G Protein-Coupled Receptor GPR139..  Scientific reports,  (36681-36681).  [PMID:27830715]
127. Zhongya Qin,Qiqi Sun,Yue Lin,Sicong He,Xuesong Li,Congping Chen,Wanjie Wu,Yi Luo,Jianan Y Qu.  (2018-07-10)  New fluorescent compounds produced by femtosecond laser surgery in biological tissues: the mechanisms..  Biomedical optics express,  ((7)): (3373-3390).  [PMID:29984103]
128. Lu Jin,Haizhou Sun,Sang Dan,Shengli Li,Chongzhi Zhang,Chunhua Zhang,Xiaoping Ren,Dan Shan,Shuli Ling.  (2019-11-08)  Serotonin regulates maternal calcium homeostasis during the perinatal period of sheep..  Journal of animal science,  97  ((12)): (5009-5015).  [PMID:31697833]
129. Jaturong Kumla,Nakarin Suwannarach,Kenji Matsui,Saisamorn Lumyong.  (2020-01-04)  Biosynthetic pathway of indole-3-acetic acid in ectomycorrhizal fungi collected from northern Thailand..  PloS one,  15  ((1)): (e0227478-e0227478).  [PMID:31899917]
130. Paulo V O Toledo,Oigres D Bernardinelli,Edvaldo Sabadini,Denise F S Petri.  (2020-09-14)  The states of water in tryptophan grafted hydroxypropyl methylcellulose hydrogels and their effect on the adsorption of methylene blue and rhodamine B..  Carbohydrate polymers,  248  (116765-116765).  [PMID:32919561]
131. Zhichao Liu,Qiang Shi,Don Ding,Reagan Kelly,Hong Fang,Weida Tong.  (2011-12-24)  Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps)..  PLoS computational biology,  ((12)): (e1002310-e1002310).  [PMID:22194678]
132. Jian-Zhuang Tan,Yu-Ming Guo,Todd J Applegate,En-Cun Du,Xu Zhao.  (2014-04-15)  Dietary L-arginine modulates immunosuppression in broilers inoculated with an intermediate strain of infectious bursa disease virus..  Journal of the science of food and agriculture,  95  ((1)): (126-135).  [PMID:24728981]
133. Cyprian E Oshoma,Darren Greetham,Edward J Louis,Katherine A Smart,Trevor G Phister,Chris Powell,Chenyu Du.  (2015-08-19)  Screening of Non- Saccharomyces cerevisiae Strains for Tolerance to Formic Acid in Bioethanol Fermentation..  PloS one,  10  ((8)): (e0135626-e0135626).  [PMID:26284784]
134. Kenneth S Brandenburg,Diego F Calderon,Patricia R Kierski,Amanda L Brown,Nihar M Shah,Nicholas L Abbott,Michael J Schurr,Christopher J Murphy,Jonathan F McAnulty,Charles J Czuprynski.  (2015-09-06)  Inhibition of Pseudomonas aeruginosa biofilm formation on wound dressings..  Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society,  23  ((6)): (842-854).  [PMID:26342168]

Solution Calculators