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L6H21 , CAS No.L611397, Inhibitor of lymphocyte antigen 96

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L6H21 , CAS No.L611397, Inhibitor of lymphocyte antigen 96

Moligand™

PubChem CID: 5346378

Item Number

L611397

Grouped product items
SKU	Size	Availability	Price	Qty
L611397-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
L611397-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,001.90

View related series

lymphocyte antigen 96 Inhibitor

Basic Description

Synonyms	L6H21 \| 18778-38-6 \| (E)-3-(2,3-dimethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one \| (2E)-3-(2,3-Dimethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one \| (e)-2,3-dimethoxy-4'-methoxychalcone \| MD-2 inhibitor L6H21 \| 2,3,4'-trimethoxychalcone \| GTPL9027 \| CHEMBL2013139 \| DTXS
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of lymphocyte antigen 96

Associated Targets(Human)

LY96 Tchem Lymphocyte antigen 96 (1 Activities)

Discover Target: LY96

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HT-29 (80576 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SGC-7901 (2773 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Toxoplasma gondii (4585 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RAW264.7 (28094 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	(E)-3-(2,3-dimethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one
INCHI	InChI=1S/C18H18O4/c1-20-15-10-7-13(8-11-15)16(19)12-9-14-5-4-6-17(21-2)18(14)22-3/h4-12H,1-3H3/b12-9+
InChi Key	IECVLMVZGCYCSZ-FMIVXFBMSA-N
Canonical SMILES	COc1ccc(cc1)C(=O)/C=C/c1cccc(c1OC)OC
Isomeric SMILES	COC1=CC=C(C=C1)C(=O)/C=C/C2=C(C(=CC=C2)OC)OC
PubChem CID	5346378

Database links

PubChem CID	5346378
ChEMBL Ligand	CHEMBL2013139

Certificates

Certificate of Analysis(COA)

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References

1. Wang Y, Shan X, Chen G, Jiang L, Wang Z, Fang Q, Liu X, Wang J, Zhang Y, Wu W et al.. (2015) MD-2 as the target of a novel small molecule, L6H21, in the attenuation of LPS-induced inflammatory response and sepsis.. Br J Pharmacol, 172 (17): (4391-405). [PMID:26076332]

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L6H21 , CAS No.L611397, Inhibitor of lymphocyte antigen 96

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Related Documents

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator