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Lalistat 1 - ≥98%(HPLC), high purity , CAS No.501104-16-1

≥98%(HPLC)

CAS#: 501104-16-1
Formula: C₁₂H₁₈N₄O₃S
Molecular Weight: 298.36
PubChem CID: 651937

Item Number

L287177

Grouped product items
SKU	Size	Availability	Price
L287177-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$124.90
L287177-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$190.90
L287177-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$429.90
L287177-50mg	50mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$801.90

Potent and selective LAL inhibitor

Basic Description

Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Potent and selective lysosomal acid lipase (LAL) inhibitor (IC50= 68 nM). Exhibits no significant activity against pancreatic lipase or lipoprotein lipase at 10 μM concentration. Blocks LAL-mediated lipid hydrolysis of acetylated LDL and reduces efflux of
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Associated Targets(Human)

LIPA Tchem Lysosomal acid lipase/cholesteryl ester hydrolase (1 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LIPA Tchem Lysosomal acid lipase/cholesteryl ester hydrolase (63 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GNAS Tbio Guanine nucleotide-binding protein G(s), subunit alpha (103405 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Pseudomonas aeruginosa (123386 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Acinetobacter baumannii (41033 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	(4-piperidin-1-yl-1,2,5-thiadiazol-3-yl) morpholine-4-carboxylate
INCHI	InChI=1S/C12H18N4O3S/c17-12(16-6-8-18-9-7-16)19-11-10(13-20-14-11)15-4-2-1-3-5-15/h1-9H2
InChi Key	XAWUWPUYJUOUOF-UHFFFAOYSA-N
Canonical SMILES	C1CCN(CC1)C2=NSN=C2OC(=O)N3CCOCC3
Isomeric SMILES	C1CCN(CC1)C2=NSN=C2OC(=O)N3CCOCC3
PubChem CID	651937
Molecular Weight	298.36

Certificates

Certificate of Analysis(COA)

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5 results found

Lot Number	Certificate Type	Date	Item
J2209414	Certificate of Analysis	Sep 13, 2022	L287177
J2209415	Certificate of Analysis	Sep 13, 2022	L287177
J2209411	Certificate of Analysis	Sep 08, 2022	L287177
J2209412	Certificate of Analysis	Sep 08, 2022	L287177
J2209413	Certificate of Analysis	Sep 08, 2022	L287177

Solubility

Solvent:DMSO, Max Conc. mg/mL: 29.84, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 29.84, Max Conc. mM: 100

Sensitivity

Moisture sensitive

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Lalistat 1 - ≥98%(HPLC), high purity , CAS No.501104-16-1

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

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