Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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L129788-5g | 5g | In stock | $9.90 | |
L129788-25g | 25g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $27.90 | |
L129788-100g | 100g | In stock | $105.90 |
Synonyms | 4-amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one | HMS3259F08 | HSDB 7155 | LAMIVUDINE [JAN] | LAMIVUDINE [USP-RS] | (-)-(2'R,5'S)-1-[2'-Hydroxymethyl-5'-(1,3-oxathiolanyl)]cytosine | 3TC and NV-01 | 4-Amino-1-((2R,5S)-2-(hydro |
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Specifications & Purity | ≥99% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Action Type | INHIBITOR |
Mechanism of action | Human immunodeficiency virus type 1 reverse transcriptase inhibitor |
Note | 1g售完停产,不再备货 |
ALogP | -0.9 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one |
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INCHI | InChI=1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m0/s1 |
InChi Key | JTEGQNOMFQHVDC-NKWVEPMBSA-N |
Canonical SMILES | C1C(OC(S1)CO)N2C=CC(=NC2=O)N |
Isomeric SMILES | C1[C@H](O[C@H](S1)CO)N2C=CC(=NC2=O)N |
WGK Germany | 3 |
RTECS | UW7361333 |
PubChem CID | 60825 |
Molecular Weight | 229.26 |
Reaxy-Rn | 5480511 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
F2214804 | Certificate of Analysis | Mar 19, 2024 | L129788 |
F2214805 | Certificate of Analysis | Mar 19, 2024 | L129788 |
F2214806 | Certificate of Analysis | Mar 19, 2024 | L129788 |
K2321384 | Certificate of Analysis | Nov 09, 2023 | L129788 |
K2321385 | Certificate of Analysis | Nov 09, 2023 | L129788 |
K2321387 | Certificate of Analysis | Nov 09, 2023 | L129788 |
D2315318 | Certificate of Analysis | May 31, 2022 | L129788 |
Solubility | (soluble): water and methanol; Solubility in water: 70000 mg / L 20 ° C |
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Sensitivity | Heat sensitive |
Specific Rotation[α] | [α]D:-142°(C=1,MeOH) |
Melt Point(°C) | 177 °C |
Pictogram(s) | GHS08, GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H373:Causes damage to organs through prolonged or repeated exposure H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | UW7361333 |
Reaxy-Rn | 5480511 |
1. Chaosheng Yuan, Jian Wang, Ying Xu, Yongfu Liang, Shiquan Feng, Xiang Zhu, Haining Li. (2023) High-pressure Polymorphism in Lamivudine. JOURNAL OF MOLECULAR STRUCTURE, 1292 (136170). [PMID:] [10.1016/j.molstruc.2023.136170] |
1. Chaosheng Yuan, Jian Wang, Ying Xu, Yongfu Liang, Shiquan Feng, Xiang Zhu, Haining Li. (2023) High-pressure Polymorphism in Lamivudine. JOURNAL OF MOLECULAR STRUCTURE, 1292 (136170). [PMID:] [10.1016/j.molstruc.2023.136170] |