Lamotrigine - ≥98%, high purity , Sodium channel alpha subunit blocker, CAS No.84057-84-1, Sodium channel alpha subunit blocker

Item Number

L129555

• Synonyms: LTG | CHEBI:6367 | Lamictal | Tocris-1611 | AKOS005561147 | BDBM50031299 | HMS3268G17 | Lamotrigine Extended Release | Opera_ID_12 | Lamotrigina [Spanish] | Lamotrigine (JAN/USP/INN) | LAMOTRIGINE [JAN] | SCHEMBL35439 | C9H7Cl2N5 | HMS2089M08 | KS-1074 |
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Lamotrigine is a phenyltriazine sodium channel protein inhibitor of presynaptic neurons. Studies indicate that Lamotrigine blocked sustained repetitive firing of neurons in a dose dependent manner in cultured mouse spinal cords. These studies indicate tha
• Storage Temp: Store at 2-8°C,Argon charged
• Shipped In: Wet ice
• Grade: Moligand™
• Action Type: BLOCKER, CHANNEL BLOCKER
• Mechanism of action: Sodium channel alpha subunit blocker
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Lamotrigine is a novel anticonvulsant drug for inhibition of 5-HT with IC50 of 240 μM and 474 μM in human platelets and rat brain synaptosomes, and also is a sodium channel blocker.
A sodium channel protein inhibitor.