Lanosterol - >95%, high purity , CAS No.79-63-0

Item Number
L130208
Grouped product items
SKUSizeAvailabilityPrice Qty
L130208-1mg
1mg
In stock
$91.90
L130208-5mg
5mg
In stock
$410.90
L130208-10mg
10mg
In stock
$738.90
L130208-25mg
25mg
In stock
$1,662.90
L130208-50mg
50mg
In stock
$2,991.90

Steroid bioprecursor. CYP51A1 component.

View related series
Farnesoid X receptor-β Agonist

Basic Description

SynonymsAKOS024307002 | 3beta-Hydroxy-8,24-lanostadiene | C4CA2F34-1C1A-4673-AC43-E547708CB228 | LANOSTEROL [INCI] | Lanster | NSC 60677 | Cholesta-8, 4,4,14-trimethyl-, (3.beta.,5.alpha.)- | Cryptosterol | Botalan base | CS-0031956 | Lanosta-8,24-dien-3-ol, (3-b
Specifications & PurityMoligand™, ≥95%
Biochemical and Physiological MechanismsSteroid bioprecursor. CYP51A1 component. Cholesterol precursor. Shows anti-inflammatory effects in vivo.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Lanosterol, an amphipathic molecule, that is produced by lanosterol synthase (LSS). It is enriched in the lens.

Associated Targets(Human)

CRYBB2 Tbio Beta-crystallin B2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CRYAA Tchem Alpha-crystallin A chain (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CRYGC Tbio Gamma-crystallin C (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CRYGD Tbio Gamma-crystallin D (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CRYAB Tchem Alpha-crystallin B chain (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP51A1 Tchem Lanosterol 14-alpha demethylase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PPARA Tclin Peroxisome proliferator-activated receptor alpha (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PPARA Tclin Peroxisome proliferator-activated receptor alpha (9197 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PANC-1 (6144 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Raji (5516 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CRYAB Tchem Alpha-crystallin B chain (132 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CRYAA Tchem Alpha-crystallin A chain (85 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CRYBB2 Tbio Beta-crystallin B2 (41 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CRYGC Tbio Gamma-crystallin C (41 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

ERG11 Cytochrome P450 51 (617 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human gammaherpesvirus 4 (1538 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
cyp125 Putative cytochrome P450 125 (56 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Phytophthora cactorum (113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
cyp51B 14-alpha sterol demethylase (11 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488188991
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488188991
IUPAC Name (3S,5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
INCHI InChI=1S/C30H50O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h10,21-22,25-26,31H,9,11-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1
InChi Key CAHGCLMLTWQZNJ-BQNIITSRSA-N
Canonical SMILES CC(CCC=C(C)C)C1CCC2(C1(CCC3=C2CCC4C3(CCC(C4(C)C)O)C)C)C
Isomeric SMILES C[C@H](CCC=C(C)C)[C@H]1CC[C@@]2([C@@]1(CCC3=C2CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C
PubChem CID 246983
Molecular Weight 426.717

Certificates

Certificate of Analysis(COA)

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13 results found

Lot NumberCertificate TypeDateItem
E23231076Certificate of AnalysisFeb 23, 2023 L130208
E2323952Certificate of AnalysisFeb 23, 2023 L130208
E2323953Certificate of AnalysisFeb 23, 2023 L130208
E2323955Certificate of AnalysisFeb 23, 2023 L130208
E2323956Certificate of AnalysisFeb 23, 2023 L130208
E2323957Certificate of AnalysisFeb 23, 2023 L130208
E2323959Certificate of AnalysisFeb 23, 2023 L130208
E2323960Certificate of AnalysisFeb 23, 2023 L130208
I2222532Certificate of AnalysisSep 27, 2022 L130208
H2223034Certificate of AnalysisAug 26, 2022 L130208
I2025345Certificate of AnalysisAug 09, 2022 L130208
I2025346Certificate of AnalysisAug 09, 2022 L130208
I2025344Certificate of AnalysisAug 09, 2022 L130208

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Chemical and Physical Properties

SolubilityLanosterol has been used as a standard in HPLC for the quantification in testis samples.

Related Documents

Solution Calculators