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Lansoprazole - ≥98%, high purity , Potassium-transporting ATPase inhibitor, CAS No.103577-45-3, Potassium-transporting ATPase inhibitor

Moligand™
≥98%

CAS#: 103577-45-3
Formula: C₁₆H₁₄F₃N₃O₂S
Molecular Weight: 369.36
MDL number: MFCD00866873
PubChem CID: 3883

Item Number

L129650

Grouped product items
SKU	Size	Availability	Price
L129650-250mg	250mg	In stock	$23.90
L129650-1g	1g	In stock	$77.90
L129650-5g	5g	In stock	$338.90
L129650-25g	25g	In stock	$1,525.90
L129650-100g	100g	In stock	$5,491.90

H+,K+-ATPase inhibitor

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Benzimidazoles Five-Membered Heterocyclic Compounds

Basic Description

Synonyms	lansoprazole\|103577-45-3\|Prevacid\|Limpidex\|Agopton\|Lanzor\|Bamalite\|Monolitum\|Takepron\|Ogastro\|Prevacid SoluTab\|Lansoprazol\|Lanzopral\|Opiren\|Zoton\|Lanproton\|Lansopep\|Lasoprol\|Mesactol\|Aprazol\|Blason\|Ketian\|Lancid\|Lanston\|Lanz\|AG-1749\|lanzoprazole\|Lansopraz
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	H+,K+-ATPase inhibitor (IC50= 6.3μM) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC50= 0.09μM for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. A
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Potassium-transporting ATPase inhibitor
Note	250mg卖完停产，不再备货
Product Description	Lansoprazole is a ATP4A (H+,K+-ATPase) inhibitor (IC50 = 6.3 μM) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC50 = 0.09 μM for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacterial against Helicobacter pylori in vitro. Also blocks swelling-dependent chloride channel (ICI swell) in NIH3T3 fibroblasts. Lansoprazole is more potent than omeprazole A H+,K+-ATPase inhibitor that displays antisecretory activity

Names and Identifiers

IUPAC Name	2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1H-benzimidazole
INCHI	InChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)
InChi Key	MJIHNNLFOKEZEW-UHFFFAOYSA-N
Canonical SMILES	CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F
Isomeric SMILES	CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F
WGK Germany	2
RTECS	DD9487500
PubChem CID	3883
Molecular Weight	369.36
Reaxy-Rn	4333393

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6 results found

Lot Number	Certificate Type	Date	Item
G2402348	Certificate of Analysis	Apr 02, 2024	L129650
L2111246	Certificate of Analysis	Sep 21, 2023	L129650
K2223277	Certificate of Analysis	Nov 25, 2022	L129650
B1918060	Certificate of Analysis	Oct 15, 2022	L129650
B1918063	Certificate of Analysis	Oct 15, 2022	L129650
B1528009	Certificate of Analysis	Sep 19, 2022	L129650

Solubility

Solvent:1eq. HCl, Max Conc. mg/mL: 18.47, Max Conc. mM: 50; Solvent:DMSO, Max Conc. mg/mL: 36.94, Max Conc. mM: 100

Sensitivity

Heat Sensitive

Melt Point(°C)

173-175°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	2
RTECS	DD9487500
Reaxy-Rn	4333393
Merck Index	5362

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Lansoprazole - ≥98%, high purity , Potassium-transporting ATPase inhibitor, CAS No.103577-45-3, Potassium-transporting ATPase inhibitor

Basic Description

Product Properties

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

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