Lansoprazole - ≥98%, high purity , Potassium-transporting ATPase inhibitor, CAS No.103577-45-3, Potassium-transporting ATPase inhibitor

Item Number

L129650

• Synonyms: 2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl)methyl)sulfinyl)benzimidazole | Compraz | Lansoprazole-13C6 | Lansoprazole [USAN:USP:INN:BAN] | Prevacid SoluTab | 2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole | LA
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: H+,K+-ATPase inhibitor (IC50= 6.3μM) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC50= 0.09μM for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. A
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Potassium-transporting ATPase inhibitor
• Note: 250mg卖完停产，不再备货

Product Description

Lansoprazole is a ATP4A (H+,K+-ATPase) inhibitor (IC50 = 6.3 μM) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC50 = 0.09 μM for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacterial against Helicobacter pylori in vitro. Also blocks swelling-dependent chloride channel (ICI swell) in NIH3T3 fibroblasts. Lansoprazole is more potent than omeprazole
A H+,K+-ATPase inhibitor that displays antisecretory activity