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L464031-10mg

10mg

Available within 8-12 weeks(?)

$1,237.90

Basic Description

Synonyms	4-[(2S,3R,4R)-4-(4-hydroxy-3-methoxybenzyl)-3-(hydroxymethyl)tetrahydrofuran-2-yl]-2-methoxyphenol \| NSC329247 \| NSC-329247 \| 4-[[(3R,4R,5S)-4-(hydroxymethyl)-5-(3-methoxy-4-oxidanyl-phenyl)oxolan-3-yl]methyl]-2-methoxy-phenol \| 3-Furanmethanol,tetrahydro
Specifications & Purity	≥95%(HPLC)
Product Description	Description Lariciresinol may be used as a reference compound in the purification, identification and analysis of lignan phytoestrogens and lignan glycosides.

Associated Targets(Human)

CYP2D6 Tclin Cytochrome P450 2D6 (0 Activities)

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CYP3A4 Tclin Cytochrome P450 3A4 (0 Activities)

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PTPN1 Tchem Tyrosine-protein phosphatase non-receptor type 1 (0 Activities)

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CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)

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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

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SK-MEL-2 (46422 Activities)

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SK-OV-3 (52876 Activities)

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XF498 (12972 Activities)

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A549 (127892 Activities)

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HepG2 (196354 Activities)

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BL-41 (110 Activities)

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Associated Targets(non-human)

Ptpn1 Protein-tyrosine phosphatase 1B (270 Activities)

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Aspergillus niger (16508 Activities)

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Penicillium (212 Activities)

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Human alphaherpesvirus 1 (11089 Activities)

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Vesicular stomatitis virus (4460 Activities)

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Lepidium sativum (398 Activities)

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P388 (20296 Activities)

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RAW264.7 (28094 Activities)

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C6 (2371 Activities)

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BV-2 (3710 Activities)

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Lactuca sativa (1092 Activities)

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Allium cepa (293 Activities)

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Solanum lycopersicum (493 Activities)

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Lolium multiflorum (260 Activities)

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	4-[[(3R,4R,5S)-5-(4-hydroxy-3-methoxyphenyl)-4-(hydroxymethyl)oxolan-3-yl]methyl]-2-methoxyphenol
INCHI	InChI=1S/C20H24O6/c1-24-18-8-12(3-5-16(18)22)7-14-11-26-20(15(14)10-21)13-4-6-17(23)19(9-13)25-2/h3-6,8-9,14-15,20-23H,7,10-11H2,1-2H3/t14-,15-,20+/m0/s1
InChi Key	MHXCIKYXNYCMHY-AUSJPIAWSA-N
Canonical SMILES	COC1=C(C=CC(=C1)CC2COC(C2CO)C3=CC(=C(C=C3)O)OC)O
Isomeric SMILES	COC1=C(C=CC(=C1)C[C@H]2CO[C@@H]([C@H]2CO)C3=CC(=C(C=C3)O)OC)O
PubChem CID	332427
UN Number	3077
Molecular Weight	360.4
Beilstein	4560057

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Flash Point(°F)	Not applicable
Flash Point(°C)	Not applicable

Safety and Hazards(GHS)

Pictogram(s)	GHS09
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H400:Very toxic to aquatic life
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P501:Dispose of contents/container to ... P391:Collect spillage.
Class	9
RIDADR	UN 3077 9 / PGIII

References

1. Heidi Schwartz,Gerhard Sontag. (2006-06-06) Determination of secoisolariciresinol, lariciresinol and isolariciresinol in plant foods by high performance liquid chromatography coupled with coulometric electrode array detection.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 838 ((2)): (78-85). [PMID:16750660]
2. Bomi Hwang,Jaeyong Cho,In-sok Hwang,Hong-Guang Jin,Eun-Rhan Woo,Dong Gun Lee. (2011-06-18) Antifungal activity of lariciresinol derived from Sambucus williamsii and their membrane-active mechanisms in Candida albicans.. Biochemical and biophysical research communications, 410 ((3)): (489-493). [PMID:21679690]
3. Alexandrine During,Céline Debouche,Thomas Raas,Yvan Larondelle. (2012-09-08) Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells.. The Journal of nutrition, 142 ((10)): (1798-1805). [PMID:22955517]
4. Niina M Saarinen,Anni Wärri,Ruud P M Dings,Maarit Airio,Annika I Smeds,Sari Mäkelä. (2008-06-06) Dietary lariciresinol attenuates mammary tumor growth and reduces blood vessel density in human MCF-7 breast cancer xenografts and carcinogen-induced mammary tumors in rats.. International journal of cancer, 123 ((5)): (1196-1204). [PMID:18528864]
5. Hisashi Nishiwaki,Mitsuko Kumamoto,Yoshihiro Shuto,Satoshi Yamauchi. (2011-11-10) Stereoselective syntheses of all stereoisomers of lariciresinol and their plant growth inhibitory activities.. Journal of agricultural and food chemistry, 59 ((24)): (13089-13095). [PMID:22066904]
6. Simone Angeloni,Luciano Navarini,Gianni Sagratini,Elisabetta Torregiani,Sauro Vittori,Giovanni Caprioli. (2018-06-21) Development of an extraction method for the quantification of lignans in espresso coffee by using HPLC-MS/MS triple quadrupole.. Journal of mass spectrometry : JMS, 53 ((9)): (842-848). [PMID:29925121]

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(+)-Lariciresinol - ≥95.0% (HPLC), high purity , CAS No.27003-73-2

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

References

Solution Calculators

Molarity Calculator

Dilution Calculator

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