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Latanoprost - ≥99%, high purity , Prostanoid FP receptor agonist, CAS No.130209-82-4, Prostanoid FP receptor agonist
FP prostaglandin receptor agonist; also exhibits agonist activity at EP1and EP3receptors
Basic Description Synonyms latanoprost|130209-82-4|Xalatan|PhXA41|PHXA-41|XA41|PhXA 41|latanoprostum|XA-41|UNII-6Z5B6HVF6O|6Z5B6HVF6O|latanoprost (isopropyl ester)|IYUZEH|XELPROS|CHEBI:6384|Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5 Specifications & Purity Moligand™, ≥99% Biochemical and Physiological Mechanisms FP prostaglandin receptor agonist; displays greater selectivity thanprostanglandin F2α. Exhibits agonist activity at EP1and EP3receptors, but little-to-no effect at EP2, DP, IP and TP prostanoid receptors. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type AGONIST Mechanism of action Prostanoid FP receptor agonist Product Description Latanoprost is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect. Latanoprost increases uveoscleral outflow and thereby reduces intraocular pressure.
Names and Identifiers IUPAC Name propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate INCHI InChI=1S/C26H40O5/c1-19(2)31-26(30)13-9-4-3-8-12-22-23(25(29)18-24(22)28)17-16-21(27)15-14-20-10-6-5-7-11-20/h3,5-8,10-11,19,21-25,27-29H,4,9,12-18H2,1-2H3/b8-3-/t21-,22+,23+,24-,25+/m0/s1 InChi Key GGXICVAJURFBLW-CEYXHVGTSA-N Canonical SMILES CC(C)OC(=O)CCCC=CCC1C(CC(C1CCC(CCC2=CC=CC=C2)O)O)O Isomeric SMILES CC(C)OC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1CC[C@H](CCC2=CC=CC=C2)O)O)O WGK Germany 3 RTECS MJ9669550 PubChem CID 5311221 Molecular Weight 432.59
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 21.63, Max Conc. mM: 50; Solvent:ethanol, Max Conc. mg/mL: 21.63, Max Conc. mM: 50 Sensitivity heat sensitive Specific Rotation[α] 34° (C=1,CHCl3) Flash Point(°C) 188 °C
Safety and Hazards(GHS) Pictogram(s) GHS06 , GHS08 Signal Danger Hazard Statements H301: Toxic if swallowed
H300: Fatal if swallowed
H361: Suspected of damaging fertility or the unborn child
Precautionary Statements P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P203: Obtain, read and follow all safety instructions before use.
P301+P316: IF SWALLOWED: Get emergency medical help immediately.
P318: if exposed or concerned, get medical advice.
WGK Germany 3 RTECS MJ9669550 Merck Index 5376
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