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Latrepirdine dihydrochloride - ≥96%, high purity , CAS No.97657-92-6
Activator of AMPK, potentiator of AMPA, inhibitor of L-type voltage-gated Ca2+ channels, NMDA, H1/2 histamine, α-adrenergic and 5-HT2C/5A/6 receptors
Basic Description Synonyms A915372 | 2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole 2HCl | 2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole;dihydrochloride | AS-59712 | CS-5771 | GTWLIQOLGOZTLF-UHFFFAOYSA-N | Specifications & Purity ≥96% Biochemical and Physiological Mechanisms Activator of AMPK,\xa0 potentiator of AMPA, and an inhibitor of L-type voltage-gated Ca2+ channels, NMDA receptors, H1/2 histamine receptors, α-adrenergic receptors, and 5-HT2C/5A/6 receptors. Displays neuroprotective and cognition enhancing effects in ne Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Note Toxic, refer to SDS for further information . Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name 2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole;dihydrochloride INCHI InChI=1S/C21H25N3.2ClH/c1-15-4-7-20-18(12-15)19-14-23(3)10-9-21(19)24(20)11-8-17-6-5-16(2)22-13-17;;/h4-7,12-13H,8-11,14H2,1-3H3;2*1H InChi Key GTWLIQOLGOZTLF-UHFFFAOYSA-N Canonical SMILES CC1=CC2=C(C=C1)N(C3=C2CN(CC3)C)CCC4=CN=C(C=C4)C.Cl.Cl Isomeric SMILES CC1=CC2=C(C=C1)N(C3=C2CN(CC3)C)CCC4=CN=C(C=C4)C.Cl.Cl PubChem CID 23729232 Molecular Weight 392.37
Chemical and Physical Properties Solubility DMSO 24 mg/mL Water 79 mg/mL Ethanol 13 mg/mL Sensitivity moisture sensitive
Safety and Hazards(GHS) Pictogram(s) GHS08 , GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H302: Harmful if swallowed
H361: Suspected of damaging fertility or the unborn child
Precautionary Statements P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P362+P364: Take off contaminated clothing and wash it before reuse.
P330: Rinse mouth.
P203: Obtain, read and follow all safety instructions before use.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P301+P317: IF SWALLOWED: Get medical help.
P318: if exposed or concerned, get medical advice.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
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