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LDN-192960 dihydrochloride - 98% (HPLC), high purity , CAS No.184582-62-5

  • ≥98%(HPLC)
Item Number
L168104
Grouped product items
SKUSizeAvailabilityPrice Qty
L168104-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$139.90
L168104-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$229.90
L168104-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$429.90
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View related series
Cell Cycle/DNA Damage DYRK Haspin Kinase Protein Tyrosine Kinase/RTK

Basic Description

SynonymsAC-35777 | HY-13455 | BCP06879 | CS-7964 | EX-A4806 | MFCD02752814 | CCRIS 8174 | 3-[(2,7-Dimethoxyacridin-9-yl)thio]propan-1-amine | LDN192960 | LDN-192960 | 3-(2,7-dimethoxyacridin-9-ylthio)propan-1-amine | 2,7-Dimethoxy-9-(3'-aminopropyl)thioacridine |
Specifications & Purity≥98%(HPLC)
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

LDN-192960 is a potent inhibitor of Haspin and DYRK2 (IC50s: 10 nM and 48 nM).

Associated Targets(Human)

GSK3B Tclin Glycogen synthase kinase-3 beta (11785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CSNK1E Tclin Casein kinase I epsilon (1412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DYRK1A Tchem Dual-specificity tyrosine-phosphorylation regulated kinase 1A (6484 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CLK1 Tchem Dual specificty protein kinase CLK1 (2189 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CLK2 Tchem Dual specificity protein kinase CLK2 (3942 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CLK3 Tchem Dual specificity protein kinase CLK3 (2711 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CLK4 Tchem Dual specificity protein kinase CLK4 (4053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DYRK2 Tchem Dual-specificity tyrosine-phosphorylation regulated kinase 2 (2095 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DYRK3 Tchem Dual-specificity tyrosine-phosphorylation regulated kinase 3 (1018 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DYRK1B Tchem Dual specificity tyrosine-phosphorylation-regulated kinase 1B (2654 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DYRK4 Tchem Dual specificity tyrosine-phosphorylation-regulated kinase 4 (692 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

HT-22 (3261 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 3-(2,7-dimethoxyacridin-9-yl)sulfanylpropan-1-amine
INCHI InChI=1S/C18H20N2O2S/c1-21-12-4-6-16-14(10-12)18(23-9-3-8-19)15-11-13(22-2)5-7-17(15)20-16/h4-7,10-11H,3,8-9,19H2,1-2H3
InChi Key ZFOMCSNUEHMROO-UHFFFAOYSA-N
Canonical SMILES COC1=CC2=C(C=C1)N=C3C=CC(=CC3=C2SCCCN)OC
Isomeric SMILES COC1=CC2=C(C=C1)N=C3C=CC(=CC3=C2SCCCN)OC
PubChem CID 53390843
Molecular Weight 328.43

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Related Documents

 SDS

 Specification Sheet

Solution Calculators

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