Leflunomide - ≥98%, high purity , Dihydroorotate dehydrogenase inhibitor, CAS No.75706-12-6, Dihydroorotate dehydrogenase inhibitor

Item Number

L129518

• Synonyms: HWA486 | RS-34821 | L 5025 | leflunomide | SU 101 | UNII-G162GK9U4W | HMS2235C07 | HMS3371F21 | lefunamide | 5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide | KBio1_000916 | Spectrum5_000850 | HSDB 7289 | 5-Methylisoxazole-4-(4-trifluoromet
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Leflunomide is an immunosuppressive drug that inhibits T and B cell responses. Leflunomide is an inhibitor of Cox-2, of tyrosine phosphorylation (tyrosine kinase), of DHODH (dihydroorotate dehydrogenase), an enzyme for de novo pyrimidine synthesis, and of
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Dihydroorotate dehydrogenase inhibitor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD, used as an immunosuppressant agent.
An inhibitor of Cox-2 and tyrosine kinase.