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LEI-401 , CAS No.L611478, Inhibitor of N-Acylphosphatidylethanolamine-phospholipase D

LEI-401 , CAS No.L611478, Inhibitor of N-Acylphosphatidylethanolamine-phospholipase D

Item Number

L611478

Grouped product items
SKU	Size	Availability	Price	Qty
L611478-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
L611478-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,001.90

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Basic Description

Synonyms	LEI401
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of N-Acylphosphatidylethanolamine-phospholipase D

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	N-(cyclopropylmethyl)-6-[(3S)-3-hydroxypyrrolidin-1-yl]-2-[(3S)-3-phenylpiperidin-1-yl]pyrimidine-4-carboxamide
INCHI	InChI=1S/C24H31N5O2/c30-20-10-12-28(16-20)22-13-21(23(31)25-14-17-8-9-17)26-24(27-22)29-11-4-7-19(15-29)18-5-2-1-3-6-18/h1-3,5-6,13,17,19-20,30H,4,7-12,14-16H2,(H,25,31)/t19-,20+/m1/s1
InChi Key	GFHJYPQZBBHOCC-UXHICEINSA-N
Canonical SMILES	O[C@H]1CCN(C1)c1nc(nc(c1)C(=O)NCC1CC1)N1CCC[C@H](C1)c1ccccc1
Isomeric SMILES	C1C[C@H](CN(C1)C2=NC(=CC(=N2)N3CC[C@@H](C3)O)C(=O)NCC4CC4)C5=CC=CC=C5
PubChem CID	145998143

PubChem CID	145998143

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1. Mock ED, Mustafa M, Gunduz-Cinar O, Cinar R, Petrie GN, Kantae V, Di X, Ogasawara D, Varga ZV, Paloczi J et al.. (2020) Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice.. Nat Chem Biol, 16 (6): (667-675). [PMID:32393901]

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