Letrozole - 98%, high purity , Cytochrome P450 19A1 inhibitor, CAS No.112809-51-5, Cytochrome P450 19A1 inhibitor

Item Number

L129473

• Synonyms: letrozole|112809-51-5|Femara|4,4'-((1h-1,2,4-triazol-1-yl)methylene)dibenzonitrile|Letrozol|CGS 20267|Letoval|CGS-20267|Benzonitrile, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-|4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile|4-[(4-cyanophenyl)-(1,2,4-t
• Specifications & Purity: 98%
• Storage Temp: Store at -20°C
• Shipped In: Dry ice
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Cytochrome P450 19A1 inhibitor

Product Description

Letrozole has been used:

· in organoid growth assay to determine its inhibitory capacity(48)

·  to investigate steroid receptor coactivator-1 (SRC-1) mediated endogenous estrogen regulation of hippocampal PSD-95(49)

·  to determine its effects on tumor-induced hyperalgesia(50)

·  for hormonal manipulation in rats(51)

·  to study its effects on lipocalin-2 (Lcn2)(52)

·  to determine its effects on mechanical hyperalgesia and aromatase expression(53)