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Leu-Gly-Gly - 98%, high purity , CAS No.1187-50-4

≥98%

CAS#: 1187-50-4
Formula: C₁₀H₁₉N₃O₄
Molecular Weight: 245.28
Beilstein Registry Number: 1728928
EC Number: 214-698-1
MDL number: MFCD00065942
PubChem CID: 70910

Item Number

L121359

Grouped product items
SKU	Size	Availability	Price
L121359-250mg	250mg	In stock	$54.90
L121359-1g	1g	In stock	$166.90
L121359-5g	5g	In stock	$536.90

Basic Description

Synonyms	(S)-2-(2-(2-Amino-4-methylpentanamido)acetamido)acetic acid \| HY-W012003 \| L-Leu-Gly-Gly \| Q27144715 \| [2-((S)-2-Amino-4-methyl-pentanoylamino)-acetylamino]-acetic acid \| CHEBI:74538 \| l-leucylglycylglycine \| L-Leucyl-glycyl-glycine \| 0962ABF0-21F5-4144-B
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Leucylglycylglycine (DL-Leu-Gly-Gly) may be used to study the effects of branched-chain di- and tripeptides on cell envelope-associated proteinases (CEPs) activity. L-Leu-Gly-Gly may be used as a substrate to study the kinetics of tripeptide aminopeptidas
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Associated Targets(Human)

SLC15A1 Tchem Oligopeptide transporter small intestine isoform (922 Activities)

Discover Target: SLC15A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC15A2 Tchem Solute carrier family 15 member 2 (186 Activities)

Discover Target: SLC15A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	2-[[2-[[(2S)-2-amino-4-methylpentanoyl]amino]acetyl]amino]acetic acid
INCHI	InChI=1S/C10H19N3O4/c1-6(2)3-7(11)10(17)13-4-8(14)12-5-9(15)16/h6-7H,3-5,11H2,1-2H3,(H,12,14)(H,13,17)(H,15,16)/t7-/m0/s1
InChi Key	VWHGTYCRDRBSFI-ZETCQYMHSA-N
Canonical SMILES	CC(C)CC(C(=O)NCC(=O)NCC(=O)O)N
Isomeric SMILES	CC(C)C[C@@H](C(=O)NCC(=O)NCC(=O)O)N
WGK Germany	3
PubChem CID	70910
Molecular Weight	245.28
Beilstein	1728928

Certificates

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3 results found

Lot Number	Certificate Type	Date	Item
K2223417	Certificate of Analysis	Jul 15, 2022	L121359
K2223422	Certificate of Analysis	Jul 15, 2022	L121359
K2223438	Certificate of Analysis	Jul 15, 2022	L121359

References

1. Biegel A, Gebauer S, Hartrodt B, Brandsch M, Neubert K, Thondorf I. (2005) Three-dimensional quantitative structure-activity relationship analyses of beta-lactam antibiotics and tripeptides as substrates of the mammalian H+/peptide cotransporter PEPT1.. J Med Chem, 48 (13): (4410-9). [PMID:15974593] [10.1021/op500134e]
2. T Agatsuma,S Habe. (1985-12-01) Electrophoretic studies on enzymes of diploid and triploid Paragonimus westermani.. Parasitology, 91 (( Pt 3)): (489-497). [PMID:2934681]
3. S Kanda,K Sudo,T Kanno. (1984-06-01) A specific kinetic assay for tripeptide aminopeptidase in serum.. Clinical chemistry, 30 ((6)): (843-846). [PMID:6723039]
4. G F Vaeth,S J Henning. (1982-01-01) Postnatal development of peptidase enzymes in rat small intestine.. Journal of pediatric gastroenterology and nutrition, 1 ((1)): (111-117). [PMID:7186019]
5. Elvira María Hebert,Gianfranco Mamone,Gianluca Picariello,Raúl R Raya,Graciela Savoy,Pasquale Ferranti,Francesco Addeo. (2008-04-22) Characterization of the pattern of alphas1- and beta-casein breakdown and release of a bioactive peptide by a cell envelope proteinase from Lactobacillus delbrueckii subsp. lactis CRL 581.. Applied and environmental microbiology, 74 ((12)): (3682-3689). [PMID:18424544]
6. Griet Van Zeebroeck,Beatriz Monge Bonini,Matthias Versele,Johan M Thevelein. (2008-12-09) Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.. Nature chemical biology, 5 ((1)): (45-52). [PMID:19060912]
7. María B Espeche Turbay,Graciela Savoy de Giori,Elvira M Hebert. (2009-09-17) Release of the cell-envelope-associated proteinase of Lactobacillus delbrueckii subspecies lactis CRL 581 is dependent upon pH and temperature.. Journal of agricultural and food chemistry, 57 ((18)): (8607-8611). [PMID:19754175]
8. Alessandro Pedretti,Laura De Luca,Cristina Marconi,Luca Regazzoni,Giancarlo Aldini,Giulio Vistoli. (2011-07-12) Fragmental modeling of hPepT2 and analysis of its binding features by docking studies and pharmacophore mapping.. Bioorganic & medicinal chemistry, 19 ((15)): (4544-4551). [PMID:21741846]
9. L C Masek,J W Sweetenham,J M Whitehouse,U Schumacher. (1994-11-01) Immuno-, lectin-, and enzyme-histochemical characterization of human bone marrow endothelium.. Experimental hematology, 22 ((12)): (1203-1209). [PMID:7925783]

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