Leu-Gly-Gly - 98%, high purity , CAS No.1187-50-4

  • ≥98%
Item Number
L121359
Grouped product items
SKUSizeAvailabilityPrice Qty
L121359-250mg
250mg
In stock
$54.90
L121359-1g
1g
In stock
$166.90
L121359-5g
5g
In stock
$536.90

Basic Description

Synonyms(S)-2-(2-(2-Amino-4-methylpentanamido)acetamido)acetic acid | HY-W012003 | L-Leu-Gly-Gly | Q27144715 | [2-((S)-2-Amino-4-methyl-pentanoylamino)-acetylamino]-acetic acid | CHEBI:74538 | l-leucylglycylglycine | L-Leucyl-glycyl-glycine | 0962ABF0-21F5-4144-B
Specifications & Purity≥98%
Biochemical and Physiological MechanismsLeucylglycylglycine (DL-Leu-Gly-Gly) may be used to study the effects of branched-chain di- and tripeptides on cell envelope-associated proteinases (CEPs) activity. L-Leu-Gly-Gly may be used as a substrate to study the kinetics of tripeptide aminopeptidas
Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

SLC15A2 Tchem Solute carrier family 15 member 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC15A1 Tchem Solute carrier family 15 member 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC15A1 Tchem Oligopeptide transporter small intestine isoform (922 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC15A2 Tchem Solute carrier family 15 member 2 (186 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

GAP1 General amino-acid permease GAP1 (481 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 2-[[2-[[(2S)-2-amino-4-methylpentanoyl]amino]acetyl]amino]acetic acid
INCHI InChI=1S/C10H19N3O4/c1-6(2)3-7(11)10(17)13-4-8(14)12-5-9(15)16/h6-7H,3-5,11H2,1-2H3,(H,12,14)(H,13,17)(H,15,16)/t7-/m0/s1
InChi Key VWHGTYCRDRBSFI-ZETCQYMHSA-N
Canonical SMILES CC(C)CC(C(=O)NCC(=O)NCC(=O)O)N
Isomeric SMILES CC(C)C[C@@H](C(=O)NCC(=O)NCC(=O)O)N
WGK Germany 3
PubChem CID 70910
Molecular Weight 245.28
Beilstein 1728928

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
K2223417Certificate of AnalysisJul 15, 2022 L121359
K2223422Certificate of AnalysisJul 15, 2022 L121359
K2223438Certificate of AnalysisJul 15, 2022 L121359

Safety and Hazards(GHS)

WGK Germany 3

Related Documents

References

1. Biegel A, Gebauer S, Hartrodt B, Brandsch M, Neubert K, Thondorf I.  (2005)  Three-dimensional quantitative structure-activity relationship analyses of beta-lactam antibiotics and tripeptides as substrates of the mammalian H+/peptide cotransporter PEPT1..  J Med Chem,  48  (13): (4410-9).  [PMID:15974593]
2. T Agatsuma,S Habe.  (1985-12-01)  Electrophoretic studies on enzymes of diploid and triploid Paragonimus westermani..  Parasitology,  91   (( Pt 3)): (489-497).  [PMID:2934681]
3. S Kanda,K Sudo,T Kanno.  (1984-06-01)  A specific kinetic assay for tripeptide aminopeptidase in serum..  Clinical chemistry,  30  ((6)): (843-846).  [PMID:6723039]
4. G F Vaeth,S J Henning.  (1982-01-01)  Postnatal development of peptidase enzymes in rat small intestine..  Journal of pediatric gastroenterology and nutrition,  ((1)): (111-117).  [PMID:7186019]
5. Elvira María Hebert,Gianfranco Mamone,Gianluca Picariello,Raúl R Raya,Graciela Savoy,Pasquale Ferranti,Francesco Addeo.  (2008-04-22)  Characterization of the pattern of alphas1- and beta-casein breakdown and release of a bioactive peptide by a cell envelope proteinase from Lactobacillus delbrueckii subsp. lactis CRL 581..  Applied and environmental microbiology,  74  ((12)): (3682-3689).  [PMID:18424544]
6. Griet Van Zeebroeck,Beatriz Monge Bonini,Matthias Versele,Johan M Thevelein.  (2008-12-09)  Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor..  Nature chemical biology,  ((1)): (45-52).  [PMID:19060912]
7. María B Espeche Turbay,Graciela Savoy de Giori,Elvira M Hebert.  (2009-09-17)  Release of the cell-envelope-associated proteinase of Lactobacillus delbrueckii subspecies lactis CRL 581 is dependent upon pH and temperature..  Journal of agricultural and food chemistry,  57  ((18)): (8607-8611).  [PMID:19754175]
8. Alessandro Pedretti,Laura De Luca,Cristina Marconi,Luca Regazzoni,Giancarlo Aldini,Giulio Vistoli.  (2011-07-12)  Fragmental modeling of hPepT2 and analysis of its binding features by docking studies and pharmacophore mapping..  Bioorganic & medicinal chemistry,  19  ((15)): (4544-4551).  [PMID:21741846]
9. L C Masek,J W Sweetenham,J M Whitehouse,U Schumacher.  (1994-11-01)  Immuno-, lectin-, and enzyme-histochemical characterization of human bone marrow endothelium..  Experimental hematology,  22  ((12)): (1203-1209).  [PMID:7925783]

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