Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | LeucoMalachiteGreen | Malachite green leuco base | Malachite green leuco | Leucomalachite green | 4,4'-Bis(dimethylamino)triphenylmethane | Leuco malachite green | Bis(p-dimethylaminophenyl)phenylmethane | Benzenamine,4,4'-(phenylmethylene)bis[N,N-dimethy |
|---|---|
| Specifications & Purity | ≥98% |
| Biochemical and Physiological Mechanisms | Leucomalachite green (LMG) is a chief metabolite of malachite green, a triphenylmethane dye that has been used generally as an antifungal drug in the fish industry. DNA adducts formed in livers of rats fed with leucomalachite green have been observed with |
| Storage Temp | Store at 2-8°C,Protected from light |
| Shipped In | Wet ice |
| Product Description | Leucomalachite Green is a triphenylmethane dye used to detect blood. A method for testing for the presence of leucomalachite green utilizing SDS-modified maghemite nanoparticles (γ-Fe(2)O(3)) has been described. Other studies have reported various protocols useful for determining the presence of Leucomalachite green in aquatic biological systems. Leucomalachite green has been used as a reagent in presumptive tests which are used to detect invisible blood stains. |
Associated Targets(Human)
NR3C1 Tclin Glucocorticoid receptor (0 Activities)
VDR Tclin Vitamin D3 receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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RXRA Tclin Retinoic acid receptor RXR-alpha (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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NR1H4 Tclin Bile acid receptor (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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THRB Tclin Thyroid hormone receptor beta (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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PPARG Tclin Peroxisome proliferator-activated receptor gamma (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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VDR Tclin Vitamin D receptor (26531 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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RXRA Tclin Retinoid X receptor alpha (3637 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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NR1H4 Tclin Bile acid receptor FXR (6228 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| Pubchem Sid | 488183910 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488183910 |
| IUPAC Name | 4-[[4-(dimethylamino)phenyl]-phenylmethyl]-N,N-dimethylaniline |
| INCHI | InChI=1S/C23H26N2/c1-24(2)21-14-10-19(11-15-21)23(18-8-6-5-7-9-18)20-12-16-22(17-13-20)25(3)4/h5-17,23H,1-4H3 |
| InChi Key | WZKXBGJNNCGHIC-UHFFFAOYSA-N |
| Canonical SMILES | CN(C)C1=CC=C(C=C1)C(C2=CC=CC=C2)C3=CC=C(C=C3)N(C)C |
| Isomeric SMILES | CN(C)C1=CC=C(C=C1)C(C2=CC=CC=C2)C3=CC=C(C=C3)N(C)C |
| WGK Germany | 3 |
| RTECS | CY1203055 |
| PubChem CID | 67215 |
| UN Number | 3077 |
| Molecular Weight | 330.47 |
| Beilstein | 2140506 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 G2424381 | Certificate of Analysis | Aug 08, 2024 | L102032 |
| E2318477 | Certificate of Analysis | May 24, 2023 | L102032 |
| E2318482 | Certificate of Analysis | May 24, 2023 | L102032 |
| E2318498 | Certificate of Analysis | May 24, 2023 | L102032 |
| E2318500 | Certificate of Analysis | May 24, 2023 | L102032 |
| E2318502 | Certificate of Analysis | May 24, 2023 | L102032 |
| E2318520 | Certificate of Analysis | May 24, 2023 | L102032 |
Chemical and Physical Properties
| Solubility | Soluble in water (<0.1 mg/ml), chloroform, ethanol (4 mg/ml), and toluene. |
|---|---|
| Sensitivity | Light & Air Sensitive |
| Melt Point(°C) | 100-102°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS08 |
|---|---|
| Signal | Warning |
| Hazard Statements | H341:Suspected of causing genetic defects H351:Suspected of causing cancer |
| Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P281:Use personal protective equipment as required. P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. |
| WGK Germany | 3 |
| RTECS | CY1203055 |
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Citations of This Product
| 1. Jin Dong Cho, Hyeongmin Jin, Seongmoon Jung, Jaeman Son, Chang Heon Choi, Jong Min Park, Jin Sung Kim, Jung-in Kim. (2023) Development of a quasi-3D dosimeter using radiochromic plastic for patient-specific quality assurance. MEDICAL PHYSICS, 50 (10): (6624-6636). [PMID:37408321] [10.1002/mp.16541] |
| 2. Xiaorong Zhao, Qiulan Li, Hong Li, Yijie Wang, Feijian Xiao, Dezhi Yang, Qinghai Xia, Yaling Yang. (2023) SERS detection of Hg2+ and aflatoxin B1 through on–off strategy of oxidase-like Au@HgNPs/carbon dots. FOOD CHEMISTRY, 424 (136443). [PMID:37245470] [10.1016/j.foodchem.2023.136443] |
| 3. Jiangru Wang, Yan Yang, Qirui Shen, Dazhong Shen, Qi Kang. (2023) A smartphone-based long optical path colorimetric turntable for selective determination of malachite green and investigation the specific adsorption behavior of the imprinted cavities within molecularly imprinted polymers. MICROCHEMICAL JOURNAL, 190 (108629). [PMID:] [10.1016/j.microc.2023.108629] |
| 4. Jia Wang, Chengyi Hong, Zhengzhong Lin, Zhi-Yong Huang. (2022) Fluorescence detection of malachite green in fish based on aptamer and SYBR Green I. JOURNAL OF FOOD AND DRUG ANALYSIS, 30 (3): ( 369–381). [PMID:] [10.38212/2224-6614.3422] |
| 5. Jia Wang, Chen Zhao, Chengyi Hong, Zhengzhong Lin, Zhiyong Huang. (2021) Rapid detection of malachite green in fish and water based on the peroxidase-like activity of Fe3O4NPs enhanced with aptamer. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 104 (104162). [PMID:] [10.1016/j.jfca.2021.104162] |
| 6. Fu Guiyu, Weng Huanyuan, Lai Zhuzhi, Lin Zhengzhong, Huang Zhiyong. (2021) Detection of malachite green residue in aquaculture water by using a rare earth fluorescence probe. JOURNAL OF CHEMICAL SCIENCES, 133 (2): (1-8). [PMID:] [10.1007/s12039-021-01913-6] |
| 7. Jin Dong Cho, Jaeman Son, Chang Heon Choi, Jin Sung Kim, Hong-Gyun Wu, Jong Min Park, Jung-in Kim. (2020) Improvement in sensitivity of radiochromic 3D dosimeter based on rigid polyurethane resin by incorporating tartrazine. PLoS One, 15 (3): (e0230410). [PMID:32176733] [10.1371/journal.pone.0230410] |
| 8. Yaoping Hu, Zhijin Gao. (2020) Yellow emissive Se,N-codoped carbon dots toward sensitive fluorescence assay of crystal violet. JOURNAL OF HAZARDOUS MATERIALS, 388 (122073). [PMID:31968303] [10.1016/j.jhazmat.2020.122073] |
| 9. Ji Yang, Zheng-Zhong Lin, Zhi-Yong Huang. (2020) Rapid detection of trace malachite green using a fluorescence probe based on signal amplification through electrostatic self-assembly of CdTe QDs and polystyrene microsphere. MARINE POLLUTION BULLETIN, 151 (110812). [PMID:32056604] [10.1016/j.marpolbul.2019.110812] |
| 10. Fuyou Du, Lingshun Sun, Zhujun Huang, Zhengyi Chen, Zhigang Xu, Guihua Ruan, Chenxi Zhao. (2020) Electrospun reduced graphene oxide/TiO2/poly(acrylonitrile-co-maleic acid) composite nanofibers for efficient adsorption and photocatalytic removal of malachite green and leucomalachite green. CHEMOSPHERE, 239 (124764). [PMID:31527004] [10.1016/j.chemosphere.2019.124764] |
| 11. Qianqian Wang, Xiaofei Qin, Liping Geng, Yan Wang. (2019) Label-Free Electrochemical Aptasensor for Sensitive Detection of Malachite Green Based on Au Nanoparticle/Graphene Quantum Dots/Tungsten Disulfide Nanocomposites. Nanomaterials, 9 (2): (229). [PMID:30744009] [10.3390/nano9020229] |
| 12. Chunchen Zheng, Liying Zhang, Fangyuan Wang, Yueqing Cai, Shuhu Du, Zhongping Zhang. (2018) Silver nanoparticles/activated carbon composite as a facile SERS substrate for highly sensitive detection of endogenous formaldehyde in human urine by catalytic reaction. TALANTA, 188 (630). [PMID:30029423] [10.1016/j.talanta.2018.06.040] |
| 13. Ji Yang, Hao Wu, Ming-Hui Wu, Jun Zeng, Zheng-Zhong Lin, Xiao-Mei Chen, Zhi-Yong Huang. (2018) Simultaneous detection of malachite & leucomalachite green based on dual template CdTe@MIP via normal and synchronous fluorescence quenching. DYES AND PIGMENTS, 155 (171). [PMID:] [10.1016/j.dyepig.2018.03.057] |
| 14. Le Wu, Zheng-Zhong Lin, Jun Zeng, Hui-Ping Zhong, Xiao-Mei Chen, Zhi-Yong Huang. (2018) Detection of malachite green in fish based on magnetic fluorescent probe of CdTe QDs/nano-Fe3O4@MIPs. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 196 (117). [PMID:29438941] [10.1016/j.saa.2018.02.016] |
| 15. Jia Jie, Yan Shang, Lai Xiaoxia, Xu Yongzhen, Liu Tong, Xiang Yuhong. (2018) Colorimetric Aptasensor for Detection of Malachite Green in Fish Sample Based on RNA and Gold Nanoparticles. Food Analytical Methods, 11 (6): (1668-1676). [PMID:] [10.1007/s12161-017-1144-3] |
| 16. He Xiao-Mei, Ding Jun, Yu Lei, Hussain Dilshad, Feng Yu-Qi. (2016) Black phosphorus-assisted laser desorption ionization mass spectrometry for the determination of low-molecular-weight compounds in biofluids. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 408 (22): (6223-6233). [PMID:27382971] [10.1007/s00216-016-9737-z] |
| 17. Baomei Huang, Xibin Zhou, Jing Chen, Guofan Wu, Xiaoquan Lu. (2015) Determination of malachite green in fish based on magnetic molecularly imprinted polymer extraction followed by electrochemiluminescence. TALANTA, 142 (228). [PMID:26003716] [10.1016/j.talanta.2015.04.053] |
| 18. Hongzhi Wang, Yu Wang, Su Liu, Jinghua Yu, Wei Xu, Yuna Guo, Jiadong Huang. (2014) An RNA aptamer-based electrochemical biosensor for sensitive detection of malachite green. RSC Advances, 4 (105): (60987-60994). [PMID:] [10.1039/C4RA09850A] |
References
| 1. Jin Dong Cho, Hyeongmin Jin, Seongmoon Jung, Jaeman Son, Chang Heon Choi, Jong Min Park, Jin Sung Kim, Jung-in Kim. (2023) Development of a quasi-3D dosimeter using radiochromic plastic for patient-specific quality assurance. MEDICAL PHYSICS, 50 (10): (6624-6636). [PMID:37408321] [10.1002/mp.16541] |
| 2. Xiaorong Zhao, Qiulan Li, Hong Li, Yijie Wang, Feijian Xiao, Dezhi Yang, Qinghai Xia, Yaling Yang. (2023) SERS detection of Hg2+ and aflatoxin B1 through on–off strategy of oxidase-like Au@HgNPs/carbon dots. FOOD CHEMISTRY, 424 (136443). [PMID:37245470] [10.1016/j.foodchem.2023.136443] |
| 3. Jiangru Wang, Yan Yang, Qirui Shen, Dazhong Shen, Qi Kang. (2023) A smartphone-based long optical path colorimetric turntable for selective determination of malachite green and investigation the specific adsorption behavior of the imprinted cavities within molecularly imprinted polymers. MICROCHEMICAL JOURNAL, 190 (108629). [PMID:] [10.1016/j.microc.2023.108629] |
| 4. Jia Wang, Chengyi Hong, Zhengzhong Lin, Zhi-Yong Huang. (2022) Fluorescence detection of malachite green in fish based on aptamer and SYBR Green I. JOURNAL OF FOOD AND DRUG ANALYSIS, 30 (3): ( 369–381). [PMID:] [10.38212/2224-6614.3422] |
| 5. Jia Wang, Chen Zhao, Chengyi Hong, Zhengzhong Lin, Zhiyong Huang. (2021) Rapid detection of malachite green in fish and water based on the peroxidase-like activity of Fe3O4NPs enhanced with aptamer. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 104 (104162). [PMID:] [10.1016/j.jfca.2021.104162] |
| 6. Fu Guiyu, Weng Huanyuan, Lai Zhuzhi, Lin Zhengzhong, Huang Zhiyong. (2021) Detection of malachite green residue in aquaculture water by using a rare earth fluorescence probe. JOURNAL OF CHEMICAL SCIENCES, 133 (2): (1-8). [PMID:] [10.1007/s12039-021-01913-6] |
| 7. Jin Dong Cho, Jaeman Son, Chang Heon Choi, Jin Sung Kim, Hong-Gyun Wu, Jong Min Park, Jung-in Kim. (2020) Improvement in sensitivity of radiochromic 3D dosimeter based on rigid polyurethane resin by incorporating tartrazine. PLoS One, 15 (3): (e0230410). [PMID:32176733] [10.1371/journal.pone.0230410] |
| 8. Yaoping Hu, Zhijin Gao. (2020) Yellow emissive Se,N-codoped carbon dots toward sensitive fluorescence assay of crystal violet. JOURNAL OF HAZARDOUS MATERIALS, 388 (122073). [PMID:31968303] [10.1016/j.jhazmat.2020.122073] |
| 9. Ji Yang, Zheng-Zhong Lin, Zhi-Yong Huang. (2020) Rapid detection of trace malachite green using a fluorescence probe based on signal amplification through electrostatic self-assembly of CdTe QDs and polystyrene microsphere. MARINE POLLUTION BULLETIN, 151 (110812). [PMID:32056604] [10.1016/j.marpolbul.2019.110812] |
| 10. Fuyou Du, Lingshun Sun, Zhujun Huang, Zhengyi Chen, Zhigang Xu, Guihua Ruan, Chenxi Zhao. (2020) Electrospun reduced graphene oxide/TiO2/poly(acrylonitrile-co-maleic acid) composite nanofibers for efficient adsorption and photocatalytic removal of malachite green and leucomalachite green. CHEMOSPHERE, 239 (124764). [PMID:31527004] [10.1016/j.chemosphere.2019.124764] |
| 11. Qianqian Wang, Xiaofei Qin, Liping Geng, Yan Wang. (2019) Label-Free Electrochemical Aptasensor for Sensitive Detection of Malachite Green Based on Au Nanoparticle/Graphene Quantum Dots/Tungsten Disulfide Nanocomposites. Nanomaterials, 9 (2): (229). [PMID:30744009] [10.3390/nano9020229] |
| 12. Chunchen Zheng, Liying Zhang, Fangyuan Wang, Yueqing Cai, Shuhu Du, Zhongping Zhang. (2018) Silver nanoparticles/activated carbon composite as a facile SERS substrate for highly sensitive detection of endogenous formaldehyde in human urine by catalytic reaction. TALANTA, 188 (630). [PMID:30029423] [10.1016/j.talanta.2018.06.040] |
| 13. Ji Yang, Hao Wu, Ming-Hui Wu, Jun Zeng, Zheng-Zhong Lin, Xiao-Mei Chen, Zhi-Yong Huang. (2018) Simultaneous detection of malachite & leucomalachite green based on dual template CdTe@MIP via normal and synchronous fluorescence quenching. DYES AND PIGMENTS, 155 (171). [PMID:] [10.1016/j.dyepig.2018.03.057] |
| 14. Le Wu, Zheng-Zhong Lin, Jun Zeng, Hui-Ping Zhong, Xiao-Mei Chen, Zhi-Yong Huang. (2018) Detection of malachite green in fish based on magnetic fluorescent probe of CdTe QDs/nano-Fe3O4@MIPs. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 196 (117). [PMID:29438941] [10.1016/j.saa.2018.02.016] |
| 15. Jia Jie, Yan Shang, Lai Xiaoxia, Xu Yongzhen, Liu Tong, Xiang Yuhong. (2018) Colorimetric Aptasensor for Detection of Malachite Green in Fish Sample Based on RNA and Gold Nanoparticles. Food Analytical Methods, 11 (6): (1668-1676). [PMID:] [10.1007/s12161-017-1144-3] |
| 16. He Xiao-Mei, Ding Jun, Yu Lei, Hussain Dilshad, Feng Yu-Qi. (2016) Black phosphorus-assisted laser desorption ionization mass spectrometry for the determination of low-molecular-weight compounds in biofluids. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 408 (22): (6223-6233). [PMID:27382971] [10.1007/s00216-016-9737-z] |
| 17. Baomei Huang, Xibin Zhou, Jing Chen, Guofan Wu, Xiaoquan Lu. (2015) Determination of malachite green in fish based on magnetic molecularly imprinted polymer extraction followed by electrochemiluminescence. TALANTA, 142 (228). [PMID:26003716] [10.1016/j.talanta.2015.04.053] |
| 18. Hongzhi Wang, Yu Wang, Su Liu, Jinghua Yu, Wei Xu, Yuna Guo, Jiadong Huang. (2014) An RNA aptamer-based electrochemical biosensor for sensitive detection of malachite green. RSC Advances, 4 (105): (60987-60994). [PMID:] [10.1039/C4RA09850A] |