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L421166-1ml

1ml

Available within 8-12 weeks(?)

$69.90

Basic Description

Synonyms	Leucomalachite green \| 129-73-7 \| Malachite green leuco \| Leuco malachite green \| Malachite green leuco base \| 4,4'-Bis(dimethylamino)triphenylmethane \| C.I. Basic Green 4, leuco base \| Benzenamine,4,4'-(phenylmethylene)bis[N,N-dimethyl- \| LeucoMalachiteGreen \| Bis(p-dimet
Specifications & Purity	10mM in DMSO
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	Leucomalachite Green is a triphenylmethane dye used to detect blood. A method for testing for the presence of leucomalachite green utilizing SDS-modified maghemite nanoparticles (γ-Fe(2)O(3)) has been described. Other studies have reported various protocols useful for determining the presence of Leucomalachite green in aquatic biological systems.

Associated Targets(Human)

NR3C1 Tclin Glucocorticoid receptor (0 Activities)

Discover Target: NR3C1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

VDR Tclin Vitamin D3 receptor (0 Activities)

Discover Target: VDR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RXRA Tclin Retinoic acid receptor RXR-alpha (0 Activities)

Discover Target: RXRA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR1H4 Tclin Bile acid receptor (0 Activities)

Discover Target: NR1H4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

THRB Tclin Thyroid hormone receptor beta (0 Activities)

Discover Target: THRB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PPARG Tclin Peroxisome proliferator-activated receptor gamma (0 Activities)

Discover Target: PPARG

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)

Discover Target: NFE2L2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

Discover Target: NR3C1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

VDR Tclin Vitamin D receptor (26531 Activities)

Discover Target: VDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)

Discover Target: PPARG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)

Discover Target: THRB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RXRA Tclin Retinoid X receptor alpha (3637 Activities)

Discover Target: RXRA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NR1H4 Tclin Bile acid receptor FXR (6228 Activities)

Discover Target: NR1H4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	4-[[4-(dimethylamino)phenyl]-phenylmethyl]-N,N-dimethylaniline
INCHI	InChI=1S/C23H26N2/c1-24(2)21-14-10-19(11-15-21)23(18-8-6-5-7-9-18)20-12-16-22(17-13-20)25(3)4/h5-17,23H,1-4H3
InChi Key	WZKXBGJNNCGHIC-UHFFFAOYSA-N
Canonical SMILES	CN(C)C1=CC=C(C=C1)C(C2=CC=CC=C2)C3=CC=C(C=C3)N(C)C
Isomeric SMILES	CN(C)C1=CC=C(C=C1)C(C2=CC=CC=C2)C3=CC=C(C=C3)N(C)C
WGK Germany	3
RTECS	CY1203055
PubChem CID	67215
UN Number	3077
Molecular Weight	330.47
Beilstein	2140506

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Sensitivity	Light & Air Sensitive
Melt Point(°C)	100-102°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08
Signal	Warning
Hazard Statements	H341:Suspected of causing genetic defects H351:Suspected of causing cancer
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P281:Use personal protective equipment as required. P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice.
WGK Germany	3
RTECS	CY1203055

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Jin Dong Cho, Hyeongmin Jin, Seongmoon Jung, Jaeman Son, Chang Heon Choi, Jong Min Park, Jin Sung Kim, Jung-in Kim. (2023) Development of a quasi-3D dosimeter using radiochromic plastic for patient-specific quality assurance. MEDICAL PHYSICS, 50 (10): (6624-6636). [PMID:37408321] [10.1002/mp.16541]
2. Xiaorong Zhao, Qiulan Li, Hong Li, Yijie Wang, Feijian Xiao, Dezhi Yang, Qinghai Xia, Yaling Yang. (2023) SERS detection of Hg2+ and aflatoxin B1 through on–off strategy of oxidase-like Au@HgNPs/carbon dots. FOOD CHEMISTRY, 424 (136443). [PMID:37245470] [10.1016/j.foodchem.2023.136443]
3. Jiangru Wang, Yan Yang, Qirui Shen, Dazhong Shen, Qi Kang. (2023) A smartphone-based long optical path colorimetric turntable for selective determination of malachite green and investigation the specific adsorption behavior of the imprinted cavities within molecularly imprinted polymers. MICROCHEMICAL JOURNAL, 190 (108629). [PMID:] [10.1016/j.microc.2023.108629]
4. Jia Wang, Chengyi Hong, Zhengzhong Lin, Zhi-Yong Huang. (2022) Fluorescence detection of malachite green in fish based on aptamer and SYBR Green I. JOURNAL OF FOOD AND DRUG ANALYSIS, 30 (3): ( 369–381). [PMID:] [10.38212/2224-6614.3422]
5. Fu Guiyu, Weng Huanyuan, Lai Zhuzhi, Lin Zhengzhong, Huang Zhiyong. (2021) Detection of malachite green residue in aquaculture water by using a rare earth fluorescence probe. JOURNAL OF CHEMICAL SCIENCES, 133 (2): (1-8). [PMID:] [10.1007/s12039-021-01913-6]
6. Jin Dong Cho, Jaeman Son, Chang Heon Choi, Jin Sung Kim, Hong-Gyun Wu, Jong Min Park, Jung-in Kim. (2020) Improvement in sensitivity of radiochromic 3D dosimeter based on rigid polyurethane resin by incorporating tartrazine. PLoS One, 15 (3): (e0230410). [PMID:32176733] [10.1371/journal.pone.0230410]
7. Yaoping Hu, Zhijin Gao. (2020) Yellow emissive Se,N-codoped carbon dots toward sensitive fluorescence assay of crystal violet. JOURNAL OF HAZARDOUS MATERIALS, 388 (122073). [PMID:31968303] [10.1016/j.jhazmat.2020.122073]
8. Ji Yang, Zheng-Zhong Lin, Zhi-Yong Huang. (2020) Rapid detection of trace malachite green using a fluorescence probe based on signal amplification through electrostatic self-assembly of CdTe QDs and polystyrene microsphere. MARINE POLLUTION BULLETIN, 151 (110812). [PMID:32056604] [10.1016/j.marpolbul.2019.110812]
9. Fuyou Du, Lingshun Sun, Zhujun Huang, Zhengyi Chen, Zhigang Xu, Guihua Ruan, Chenxi Zhao. (2020) Electrospun reduced graphene oxide/TiO2/poly(acrylonitrile-co-maleic acid) composite nanofibers for efficient adsorption and photocatalytic removal of malachite green and leucomalachite green. CHEMOSPHERE, 239 (124764). [PMID:31527004] [10.1016/j.chemosphere.2019.124764]
10. Qianqian Wang, Xiaofei Qin, Liping Geng, Yan Wang. (2019) Label-Free Electrochemical Aptasensor for Sensitive Detection of Malachite Green Based on Au Nanoparticle/Graphene Quantum Dots/Tungsten Disulfide Nanocomposites. Nanomaterials, 9 (2): (229). [PMID:30744009] [10.3390/nano9020229]
11. Chunchen Zheng, Liying Zhang, Fangyuan Wang, Yueqing Cai, Shuhu Du, Zhongping Zhang. (2018) Silver nanoparticles/activated carbon composite as a facile SERS substrate for highly sensitive detection of endogenous formaldehyde in human urine by catalytic reaction. TALANTA, 188 (630). [PMID:30029423] [10.1016/j.talanta.2018.06.040]
12. Ji Yang, Hao Wu, Ming-Hui Wu, Jun Zeng, Zheng-Zhong Lin, Xiao-Mei Chen, Zhi-Yong Huang. (2018) Simultaneous detection of malachite & leucomalachite green based on dual template CdTe@MIP via normal and synchronous fluorescence quenching. DYES AND PIGMENTS, 155 (171). [PMID:] [10.1016/j.dyepig.2018.03.057]
13. Le Wu, Zheng-Zhong Lin, Jun Zeng, Hui-Ping Zhong, Xiao-Mei Chen, Zhi-Yong Huang. (2018) Detection of malachite green in fish based on magnetic fluorescent probe of CdTe QDs/nano-Fe3O4@MIPs. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 196 (117). [PMID:29438941] [10.1016/j.saa.2018.02.016]
14. Jia Jie, Yan Shang, Lai Xiaoxia, Xu Yongzhen, Liu Tong, Xiang Yuhong. (2018) Colorimetric Aptasensor for Detection of Malachite Green in Fish Sample Based on RNA and Gold Nanoparticles. Food Analytical Methods, 11 (6): (1668-1676). [PMID:] [10.1007/s12161-017-1144-3]
15. He Xiao-Mei, Ding Jun, Yu Lei, Hussain Dilshad, Feng Yu-Qi. (2016) Black phosphorus-assisted laser desorption ionization mass spectrometry for the determination of low-molecular-weight compounds in biofluids. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 408 (22): (6223-6233). [PMID:27382971] [10.1007/s00216-016-9737-z]
16. Baomei Huang, Xibin Zhou, Jing Chen, Guofan Wu, Xiaoquan Lu. (2015) Determination of malachite green in fish based on magnetic molecularly imprinted polymer extraction followed by electrochemiluminescence. TALANTA, 142 (228). [PMID:26003716] [10.1016/j.talanta.2015.04.053]
17. Hongzhi Wang, Yu Wang, Su Liu, Jinghua Yu, Wei Xu, Yuna Guo, Jiadong Huang. (2014) An RNA aptamer-based electrochemical biosensor for sensitive detection of malachite green. RSC Advances, 4 (105): (60987-60994). [PMID:] [10.1039/C4RA09850A]

References

1. Jin Dong Cho, Hyeongmin Jin, Seongmoon Jung, Jaeman Son, Chang Heon Choi, Jong Min Park, Jin Sung Kim, Jung-in Kim. (2023) Development of a quasi-3D dosimeter using radiochromic plastic for patient-specific quality assurance. MEDICAL PHYSICS, 50 (10): (6624-6636). [PMID:37408321] [10.1002/mp.16541]
2. Xiaorong Zhao, Qiulan Li, Hong Li, Yijie Wang, Feijian Xiao, Dezhi Yang, Qinghai Xia, Yaling Yang. (2023) SERS detection of Hg2+ and aflatoxin B1 through on–off strategy of oxidase-like Au@HgNPs/carbon dots. FOOD CHEMISTRY, 424 (136443). [PMID:37245470] [10.1016/j.foodchem.2023.136443]
3. Jiangru Wang, Yan Yang, Qirui Shen, Dazhong Shen, Qi Kang. (2023) A smartphone-based long optical path colorimetric turntable for selective determination of malachite green and investigation the specific adsorption behavior of the imprinted cavities within molecularly imprinted polymers. MICROCHEMICAL JOURNAL, 190 (108629). [PMID:] [10.1016/j.microc.2023.108629]
4. Jia Wang, Chengyi Hong, Zhengzhong Lin, Zhi-Yong Huang. (2022) Fluorescence detection of malachite green in fish based on aptamer and SYBR Green I. JOURNAL OF FOOD AND DRUG ANALYSIS, 30 (3): ( 369–381). [PMID:] [10.38212/2224-6614.3422]
5. Fu Guiyu, Weng Huanyuan, Lai Zhuzhi, Lin Zhengzhong, Huang Zhiyong. (2021) Detection of malachite green residue in aquaculture water by using a rare earth fluorescence probe. JOURNAL OF CHEMICAL SCIENCES, 133 (2): (1-8). [PMID:] [10.1007/s12039-021-01913-6]
6. Jin Dong Cho, Jaeman Son, Chang Heon Choi, Jin Sung Kim, Hong-Gyun Wu, Jong Min Park, Jung-in Kim. (2020) Improvement in sensitivity of radiochromic 3D dosimeter based on rigid polyurethane resin by incorporating tartrazine. PLoS One, 15 (3): (e0230410). [PMID:32176733] [10.1371/journal.pone.0230410]
7. Yaoping Hu, Zhijin Gao. (2020) Yellow emissive Se,N-codoped carbon dots toward sensitive fluorescence assay of crystal violet. JOURNAL OF HAZARDOUS MATERIALS, 388 (122073). [PMID:31968303] [10.1016/j.jhazmat.2020.122073]
8. Ji Yang, Zheng-Zhong Lin, Zhi-Yong Huang. (2020) Rapid detection of trace malachite green using a fluorescence probe based on signal amplification through electrostatic self-assembly of CdTe QDs and polystyrene microsphere. MARINE POLLUTION BULLETIN, 151 (110812). [PMID:32056604] [10.1016/j.marpolbul.2019.110812]
9. Fuyou Du, Lingshun Sun, Zhujun Huang, Zhengyi Chen, Zhigang Xu, Guihua Ruan, Chenxi Zhao. (2020) Electrospun reduced graphene oxide/TiO2/poly(acrylonitrile-co-maleic acid) composite nanofibers for efficient adsorption and photocatalytic removal of malachite green and leucomalachite green. CHEMOSPHERE, 239 (124764). [PMID:31527004] [10.1016/j.chemosphere.2019.124764]
10. Qianqian Wang, Xiaofei Qin, Liping Geng, Yan Wang. (2019) Label-Free Electrochemical Aptasensor for Sensitive Detection of Malachite Green Based on Au Nanoparticle/Graphene Quantum Dots/Tungsten Disulfide Nanocomposites. Nanomaterials, 9 (2): (229). [PMID:30744009] [10.3390/nano9020229]
11. Chunchen Zheng, Liying Zhang, Fangyuan Wang, Yueqing Cai, Shuhu Du, Zhongping Zhang. (2018) Silver nanoparticles/activated carbon composite as a facile SERS substrate for highly sensitive detection of endogenous formaldehyde in human urine by catalytic reaction. TALANTA, 188 (630). [PMID:30029423] [10.1016/j.talanta.2018.06.040]
12. Ji Yang, Hao Wu, Ming-Hui Wu, Jun Zeng, Zheng-Zhong Lin, Xiao-Mei Chen, Zhi-Yong Huang. (2018) Simultaneous detection of malachite & leucomalachite green based on dual template CdTe@MIP via normal and synchronous fluorescence quenching. DYES AND PIGMENTS, 155 (171). [PMID:] [10.1016/j.dyepig.2018.03.057]
13. Le Wu, Zheng-Zhong Lin, Jun Zeng, Hui-Ping Zhong, Xiao-Mei Chen, Zhi-Yong Huang. (2018) Detection of malachite green in fish based on magnetic fluorescent probe of CdTe QDs/nano-Fe3O4@MIPs. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 196 (117). [PMID:29438941] [10.1016/j.saa.2018.02.016]
14. Jia Jie, Yan Shang, Lai Xiaoxia, Xu Yongzhen, Liu Tong, Xiang Yuhong. (2018) Colorimetric Aptasensor for Detection of Malachite Green in Fish Sample Based on RNA and Gold Nanoparticles. Food Analytical Methods, 11 (6): (1668-1676). [PMID:] [10.1007/s12161-017-1144-3]
15. He Xiao-Mei, Ding Jun, Yu Lei, Hussain Dilshad, Feng Yu-Qi. (2016) Black phosphorus-assisted laser desorption ionization mass spectrometry for the determination of low-molecular-weight compounds in biofluids. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 408 (22): (6223-6233). [PMID:27382971] [10.1007/s00216-016-9737-z]
16. Baomei Huang, Xibin Zhou, Jing Chen, Guofan Wu, Xiaoquan Lu. (2015) Determination of malachite green in fish based on magnetic molecularly imprinted polymer extraction followed by electrochemiluminescence. TALANTA, 142 (228). [PMID:26003716] [10.1016/j.talanta.2015.04.053]
17. Hongzhi Wang, Yu Wang, Su Liu, Jinghua Yu, Wei Xu, Yuna Guo, Jiadong Huang. (2014) An RNA aptamer-based electrochemical biosensor for sensitive detection of malachite green. RSC Advances, 4 (105): (60987-60994). [PMID:] [10.1039/C4RA09850A]

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Leucomalachite Green - 10mM in DMSO, high purity , CAS No.129-73-7