Leukotriene E4 - ≥97%,100ug/ml in ethanol, high purity , CAS No.75715-89-8, Agonist of CysLT 1 receptor;Agonist of CysLT 2 receptor;Agonist of GPR17;Agonist of oxoglutarate receptor

Item Number

L274987

• Synonyms: (5S,6R,7E,9E,11Z,14Z)-6-(2-AMINO-2-CARBOXYETHYL)SULFANYL-5-HYDROXYICOSA-7,9,11,14-TETRAENOIC ACID | 7,9,11,14-Eicosatetraenoicacid, 6-[[(2R)-2-amino-2-carboxyethyl]thio]-5-hydroxy-, (5S,6R,7E,9E,11Z,14Z)- | LEUKOTRIEN E4 | BDBM50297387 | S-{(1R,2E,4E,6Z,9
• Specifications & Purity: Moligand™, ≥97%, 100ug/ml in ethanol
• Biochemical and Physiological Mechanisms: Partial, selective CysLT 1 and CysLT 2 agonist (EC 50 values are 55.9 and 59 nM, respectively). Induces hypotension and bronchoconstriction. Active in vivo and in vitro .
• Storage Temp: Store at -80°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: AGONIST
• Mechanism of action: Agonist of CysLT 1 receptor;Agonist of CysLT 2 receptor;Agonist of GPR17;Agonist of oxoglutarate receptor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Product Describtion:

Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4. Leukotriene E4 is one of the components of the slow reacting substance (SRS-A) of allergic reactions. Leukotriene E4 accumulates in plasma and urine, and urinary excretion of Leukotriene E4 is most commonly used as an indicator of asthma