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Neurotensin receptors
levocabastine , CAS No.79516-68-0, Agonist of NTS 2 receptor

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levocabastine , CAS No.79516-68-0, Agonist of NTS 2 receptor

Moligand™

CAS#: 79516-68-0
PubChem CID: 54385

Item Number

L611507

Grouped product items
SKU	Size	Availability	Price	Qty
L611507-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$350.90
L611507-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,226.90

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NTS2 receptor Agonist

Basic Description

Synonyms	BRD-K33453211-003-03-2 \| Cabastinum \| NCGC00179240-01 \| AKOS016013998 \| DTXSID001024637 \| BSPBio_001257 \| R-50547 \| SCHEMBL4577 \| C26H29FN2O2 \| Cabastine \| BPBio1_001382 \| CHEBI:92584 \| Q2240116 \| EN300-6481353 \| SCHEMBL152978 \| (+-)-trans-1-(cis-4-Cyano-
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of NTS 2 receptor

Associated Targets(Human)

NTSR2 Tchem Neurotensin receptor type 2 (2 Activities)

Discover Target: NTSR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NTSR2 Tchem Neurotensin receptor 2 (296 Activities)

Discover Target: NTSR2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Homo sapiens (32628 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Ntsr1 Neurotensin receptor 1 (48 Activities)

Discover Target: Ntsr1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(3S,4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenylpiperidine-4-carboxylic acid
INCHI	InChI=1S/C26H29FN2O2/c1-19-17-29(16-15-26(19,24(30)31)21-5-3-2-4-6-21)23-11-13-25(18-28,14-12-23)20-7-9-22(27)10-8-20/h2-10,19,23H,11-17H2,1H3,(H,30,31)/t19-,23?,25?,26-/m1/s1
InChi Key	ZCGOMHNNNFPNMX-YHYDXASRSA-N
Canonical SMILES	CC1CN(CCC1(C2=CC=CC=C2)C(=O)O)C3CCC(CC3)(C#N)C4=CC=C(C=C4)F
Isomeric SMILES	C[C@@H]1CN(CC[C@@]1(C2=CC=CC=C2)C(=O)O)C3CCC(CC3)(C#N)C4=CC=C(C=C4)F
Alternate CAS	79449-98-2,79516-68-0,79547-78-7 (hydrochloride)
PubChem CID	54385
MeSH Entry Terms	1-(4-cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenyl-4-piperidinecarboxylic acid;Bilina;l\u00e9vophta;levocabastine;levocabastine hydrochloride;levophta;livocab;livostin

Database links

Wikipedia	Levocabastine
ChEMBL Ligand	CHEMBL1615438
DrugBank Ligand	DB01106
CAS Registry No.	79516-68-0
PubChem CID	54385
DrugCentral Ligand	1564
GPCRdb Ligand	levocabastine

Certificates

Certificate of Analysis(COA)

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References

1. Schotte A, Leysen JE, Laduron PM. (1986) Evidence for a displaceable non-specific [3H]neurotensin binding site in rat brain.. Naunyn Schmiedebergs Arch Pharmacol, 333 (4): (400-5). [PMID:3022160] [10.1021/op500134e]

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