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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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L124802-1g | 1g | In stock | $67.90 | |
L124802-5g | 5g | In stock | $217.90 | |
L124802-25g | 25g | In stock | $978.90 | |
L124802-100g | 100g | In stock | $3,524.90 |
Potent and selective H 1 receptor antagonist
Synonyms | (R)-2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid dihydrochloride | good sense levocetirizine | LEVOCETIRIZINE HYDROCHLORIDE [JAN] | SCHEMBL1435906 | UCB 28556 | Childrens Xyzal Allergy | Levocetirizine (dihydrochloride) | Levo |
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Specifications & Purity | ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Levocetirizine hydrochloride is a nonsedating antihistamine. It is a histamine H1-receptor antagonist, the active isomer of cetirizine. Levocetirizine has high bioavailability, high affinity for and occupancy of the H1 receptor.Potent and selective H 1 re |
Shipped In | Normal |
Action Type | ANTAGONIST |
Mechanism of action | Histamine H1 receptor antagonist |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488196469 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488196469 |
IUPAC Name | 2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid;dihydrochloride |
INCHI | InChI=1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H/t21-;;/m1../s1 |
InChi Key | PGLIUCLTXOYQMV-GHVWMZMZSA-N |
Canonical SMILES | C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl |
Isomeric SMILES | C1CN(CCN1CCOCC(=O)O)[C@H](C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl |
WGK Germany | 3 |
PubChem CID | 9955977 |
Molecular Weight | 461.81 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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G1516061 | Certificate of Analysis | Mar 07, 2023 | L124802 |
D2318143 | Certificate of Analysis | Jul 22, 2022 | L124802 |
D2318147 | Certificate of Analysis | Jul 22, 2022 | L124802 |
D2318160 | Certificate of Analysis | Jul 22, 2022 | L124802 |
K2230582 | Certificate of Analysis | Jul 22, 2022 | L124802 |
K2230709 | Certificate of Analysis | Jul 22, 2022 | L124802 |
K2230721 | Certificate of Analysis | Jul 22, 2022 | L124802 |
K2230729 | Certificate of Analysis | Jul 22, 2022 | L124802 |
Solubility | Solubility in water: Completely soluble; Degree of Solubility in water: 946 g/l; Insoluble in Acetone |
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Melt Point(°C) | 214 °C |
Pictogram(s) | GHS09, GHS07 |
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Signal | Warning |
Hazard Statements | H302:Harmful if swallowed H400:Very toxic to aquatic life |
Precautionary Statements | P273:Avoid release to the environment. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P391:Collect spillage. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
WGK Germany | 3 |
Merck Index | 2022 |