Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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L288411-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $227.90 | |
L288411-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $902.90 |
Selective RXR modulator
Specifications & Purity | ≥98%(HPLC) |
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Biochemical and Physiological Mechanisms | Selective RXR modulator (Kivalues are 3, 9 and 11 nM for RXRα, RXRβand RXRγrespectively). Displays poor binding affinity for RAR isoforms (Kivalues are 2746, 3516 and >10,000 nM for RARα, RARβand RARγrespectively). Binding to RXR results in selective acti |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (2E,4E,6Z)-7-[3,5-ditert-butyl-2-(2,2-difluoroethoxy)phenyl]-3-methylocta-2,4,6-trienoic acid |
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INCHI | InChI=1S/C25H34F2O3/c1-16(12-22(28)29)10-9-11-17(2)19-13-18(24(3,4)5)14-20(25(6,7)8)23(19)30-15-21(26)27/h9-14,21H,15H2,1-8H3,(H,28,29)/b10-9+,16-12+,17-11- |
InChi Key | BHIBZAZKKARFIM-XRYBSMBUSA-N |
Canonical SMILES | CC(=CC(=O)O)C=CC=C(C)C1=C(C(=CC(=C1)C(C)(C)C)C(C)(C)C)OCC(F)F |
Isomeric SMILES | C/C(=C\C(=O)O)/C=C/C=C(/C)\C1=C(C(=CC(=C1)C(C)(C)C)C(C)(C)C)OCC(F)F |
PubChem CID | 9845057 |
Molecular Weight | 420.53 |
Enter Lot Number to search for COA:
Solubility | Solvent:DMSO, Max Conc. mg/mL: 42.05, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 21.03, Max Conc. mM: 50 |
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