Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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L276132-1g | 1g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $16.90 | |
L276132-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $62.90 | |
L276132-10g | 10g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $99.90 | |
L276132-25g | 25g | In stock | $222.90 | |
L276132-100g | 100g | In stock | $710.90 |
Voltage gated sodium channel blocker
Synonyms | Lidocaine hydrochloride|73-78-9|LIDOCAINE HCL|Xyloneural|Lidothesin|Lignocaine hydrochloride|Xylocaine Viscous|Laryng-O-jet|Xilina hydrochloride|Anestacon|Rucaina hydrochloride|Xycaine hydrochloride|Xylotox hydrochloride|Duncaine hydrochloride|Isicaine hy |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Voltage gated sodium channel blocker (IC 50 values are 42 and 210 μM for TTX-sensitive and TTX-resistant DRG channels respectively). Reduces proinflammatory cytokine production and shows anesthetic effects in vivo. |
Storage Temp | Protected from light,Store at -20°C,Desiccated |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Lidocaine hydrochloride (Lignocaine hydrochloride) inhibits sodium channels involving complex voltage and using dependence. Lidocaine hydrochloride decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine hydrochloride is an amide derivative and a agent to treat ventricular arrhythmia and an effective tumor-inhibitor. |
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IUPAC Name | 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide;hydrochloride |
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INCHI | InChI=1S/C14H22N2O.ClH/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H |
InChi Key | IYBQHJMYDGVZRY-UHFFFAOYSA-N |
Canonical SMILES | CCN(CC)CC(=O)NC1=C(C=CC=C1C)C.Cl |
Isomeric SMILES | CCN(CC)CC(=O)NC1=C(C=CC=C1C)C.Cl |
PubChem CID | 6314 |
Molecular Weight | 270.8 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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H2402016 | Certificate of Analysis | Aug 09, 2024 | L276132 |
C2421038 | Certificate of Analysis | Apr 01, 2024 | L276132 |
F2421069 | Certificate of Analysis | Apr 01, 2024 | L276132 |
C2421489 | Certificate of Analysis | Mar 02, 2024 | L276132 |
C2421490 | Certificate of Analysis | Mar 02, 2024 | L276132 |
C2421491 | Certificate of Analysis | Mar 02, 2024 | L276132 |
C2421492 | Certificate of Analysis | Mar 02, 2024 | L276132 |
K2127605 | Certificate of Analysis | Jun 14, 2023 | L276132 |
H2211325 | Certificate of Analysis | May 12, 2023 | L276132 |
H2211328 | Certificate of Analysis | May 12, 2023 | L276132 |
H2211329 | Certificate of Analysis | May 12, 2023 | L276132 |
J2307026 | Certificate of Analysis | May 12, 2023 | L276132 |
K2127609 | Certificate of Analysis | Sep 09, 2022 | L276132 |
D2306120 | Certificate of Analysis | Jun 13, 2022 | L276132 |
E2224202 | Certificate of Analysis | May 27, 2022 | L276132 |
Solubility | Soluble in water to 100 mM |
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Sensitivity | light & Moisture sensitive |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H302:Harmful if swallowed |
Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P312:IF SWALLOWED: call a POISON CENTER/doctor/... IF you feel unwell. |
Starting at $69.90