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Ligustilide - analytical standard，≥98%, high purity , CAS No.4431-01-0

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analytical standard

≥98%

CAS#: 4431-01-0
Formula: C₁₂H₁₄O₂
Molecular Weight: 190.238
PubChem CID: 5319022

Item Number

L115724

Grouped product items
SKU	Size	Availability	Price	Qty
L115724-20mg	20mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$129.90
L115724-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$259.90

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Neurotransmitter Agent Ingredients

Basic Description

Synonyms	STK500619 \| BCP09458 \| (3Z)-3-butylidene-4,5-dihydro-2-benzofuran-1-one. \| Ligustilide, >=98% (HPLC) \| s9385 \| (3Z)-3-butylidene-4,5-dihydro-2-benzofuran-1-one \| cis-ligustilide \| HY-N0401 \| 3-Butylidene-4,5-dihydro-1(3H)-isobenzofuranone;1(3H)-Isobenzofu
Specifications & Purity	analytical standard, ≥98%
Biochemical and Physiological Mechanisms	Ligustilide can inhibit the proliferation of and cell cycle progression of vascular smooth muscle cells and inhibits vasoconstriction. It increases vasodilation, anti-thrombosis, and serotonergic activity and decreases platelet aggregation.
Storage Temp	Protected from light,Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Grade	analytical standard
Product Description	Ligustilide is a phthalide derivative that has been shown to have broad applications in the study and treatment of cardiovascular diseases and ischemic brain injury.

Associated Targets(Human)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

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Associated Targets(non-human)

Htr7 Serotonin 7 (5-HT7) receptor (19 Activities)

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Hdac6 Histone deacetylase 6 (222 Activities)

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MAL62 Alpha-glucosidase MAL62 (106 Activities)

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Drosophila melanogaster (359 Activities)

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Aedes aegypti (630 Activities)

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Mus musculus (284745 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

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Trpa1 Transient receptor potential cation channel subfamily A member 1 (1003 Activities)

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Anopheles stephensi (118 Activities)

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Bemisia tabaci (599 Activities)

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Colletotrichum fragariae (147 Activities)

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Colletotrichum gloeosporioides (560 Activities)

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nAChRbeta2 Acetylcholine receptor subunit beta-like 2 (115 Activities)

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Colletotrichum acutatum (300 Activities)

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(3Z)-3-butylidene-4,5-dihydro-2-benzofuran-1-one
INCHI	InChI=1S/C12H14O2/c1-2-3-8-11-9-6-4-5-7-10(9)12(13)14-11/h5,7-8H,2-4,6H2,1H3/b11-8-
InChi Key	IQVQXVFMNOFTMU-FLIBITNWSA-N
Canonical SMILES	CCCC=C1C2=C(C=CCC2)C(=O)O1
Isomeric SMILES	CCC/C=C\1/C2=C(C=CCC2)C(=O)O1
Alternate CAS	81944-09-4
PubChem CID	5319022
Molecular Weight	190.238

Certificates

Certificate of Analysis(COA)

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6 results found

Lot Number	Certificate Type	Date	Item
J2428527	Certificate of Analysis	Oct 17, 2024	L115724
J2428528	Certificate of Analysis	Oct 17, 2024	L115724
J2428529	Certificate of Analysis	Oct 17, 2024	L115724
J2428539	Certificate of Analysis	Oct 17, 2024	L115724
G2209302	Certificate of Analysis	Apr 03, 2024	L115724
I2025148	Certificate of Analysis	Aug 05, 2022	L115724

Chemical and Physical Properties

Sensitivity	light & heat & moisture & air sensitive
Boil Point(°C)	169℃/mmHg
Melt Point(°C)	159℃

Safety and Hazards(GHS)

Pictogram(s)	GHS06
Signal	Danger
Hazard Statements	H301:Toxic if swallowed
Precautionary Statements	P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately.

Alternative Products

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Shasha He, Xuhua He, Shujuan Pan, Wenwen Jiang. (2023) Exploring the Mechanism of Chuanxiong Rhizoma against Thrombosis Based on Network Pharmacology, Molecular Docking and Experimental Verification. MOLECULES, 28 (18): (6702). [PMID:37764479] [10.3390/molecules28186702]
2. Zhengyong Wang, Yuqi Cao, Yingjie Lu, Fang Zhang, Yue Su, Yinlong Guo. (2020) Ultrasonic extraction and nebulization in real-time coupled with carbon fiber ionization mass spectrometry for rapid screening of the synthetic drugs adulterated into herbal products. ANALYTICA CHIMICA ACTA, 1136 (62). [PMID:33081950] [10.1016/j.aca.2020.08.045]

References

1. Shasha He, Xuhua He, Shujuan Pan, Wenwen Jiang. (2023) Exploring the Mechanism of Chuanxiong Rhizoma against Thrombosis Based on Network Pharmacology, Molecular Docking and Experimental Verification. MOLECULES, 28 (18): (6702). [PMID:37764479] [10.3390/molecules28186702]
2. Zhengyong Wang, Yuqi Cao, Yingjie Lu, Fang Zhang, Yue Su, Yinlong Guo. (2020) Ultrasonic extraction and nebulization in real-time coupled with carbon fiber ionization mass spectrometry for rapid screening of the synthetic drugs adulterated into herbal products. ANALYTICA CHIMICA ACTA, 1136 (62). [PMID:33081950] [10.1016/j.aca.2020.08.045]

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Ligustilide - analytical standard，≥98%, high purity , CAS No.4431-01-0

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Alternative Products

Citations of This Product

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator