Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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L126613-10mg | 10mg | In stock | $53.90 | |
L126613-50mg | 50mg | In stock | $129.90 | |
L126613-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $195.90 | |
L126613-250mg | 250mg | In stock | $441.90 | |
L126613-1g | 1g | In stock | $1,587.90 | |
L126613-5g | 5g | In stock | $7,144.90 | |
L126613-10g | 10g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $12,859.90 | |
L126613-25g | 25g | In stock | $28,934.90 | |
L126613-100g | 100g | In stock | $104,162.90 |
Protein synthesis inhibitor. Potent oxazolidinone antibiotic.
Synonyms | cid_441401 | s1408 | SMR000466335 | FT-0642294 | LINEZOLID [JAN] | LINEZOLID [USAN] | N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide | N-{[(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide |
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Specifications & Purity | Moligand™, ≥99% |
Biochemical and Physiological Mechanisms | Linezolid is a synthetic antibiotic used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics. A member of the oxazolidinone class of drugs, linezolid is active against most Gram-positive |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Bacterial 70S ribosome inhibitor |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Linezolid is a synthetic antibiotic used for the treatment of serious infections.((only for scientific research) ) |
ALogP | 0.7 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488189784 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488189784 |
IUPAC Name | N-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide |
INCHI | InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1 |
InChi Key | TYZROVQLWOKYKF-ZDUSSCGKSA-N |
Canonical SMILES | CC(=O)NCC1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F |
Isomeric SMILES | CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F |
WGK Germany | 3 |
RTECS | AC2720000 |
PubChem CID | 441401 |
Molecular Weight | 337.35 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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J2423220 | Certificate of Analysis | Oct 30, 2024 | L126613 |
J2424772 | Certificate of Analysis | Jun 15, 2024 | L126613 |
J2424773 | Certificate of Analysis | Jun 15, 2024 | L126613 |
E2417056 | Certificate of Analysis | May 25, 2024 | L126613 |
C2419105 | Certificate of Analysis | Mar 25, 2024 | L126613 |
F2214121 | Certificate of Analysis | Mar 19, 2024 | L126613 |
F2214188 | Certificate of Analysis | Mar 19, 2024 | L126613 |
F2214189 | Certificate of Analysis | Mar 19, 2024 | L126613 |
F2214192 | Certificate of Analysis | Mar 19, 2024 | L126613 |
F2412062 | Certificate of Analysis | Mar 19, 2024 | L126613 |
H1823138 | Certificate of Analysis | Feb 22, 2024 | L126613 |
H1823137 | Certificate of Analysis | Feb 22, 2024 | L126613 |
H1504022 | Certificate of Analysis | Mar 16, 2023 | L126613 |
C2226605 | Certificate of Analysis | May 25, 2022 | L126613 |
D2320049 | Certificate of Analysis | May 12, 2022 | L126613 |
J2325064 | Certificate of Analysis | May 12, 2022 | L126613 |
Solubility | Soluble in water (<1 mg/mL at 25 °C), ethanol (8 mg/mL at 25 °C), chloroform, methanol, and DMSO (68 mg/mL at 25 °C). |
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Sensitivity | Air Sensitive |
Melt Point(°C) | 179 °C |
Pictogram(s) | GHS08 |
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Signal | Danger |
Hazard Statements | H372:Causes damage to organs through prolonged or repeated exposure |
Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | AC2720000 |
1. Chong-Fa Lai, Wei-Bin Xiao, Hua-Cheng Yan, Hui Yang, Lu-Xia Wang, Hui Guan, Qiu-ju Peng, Zhi-Rong Deng, Jian-Wen Chen, Lin-Kun An, Lei Shi. (2020) ZTW-41, a Potent Indolizinoquinoline-5,12-Dione Derivative Against Drug-Resistant Staphylococci and Enterococci Bacteria. Microbial Drug Resistance, 26 (2): (100-109). [PMID:31441704] |
1. Birmingham MC, Rayner CR, Meagher AK, Flavin SM, Batts DH, Schentag JJ. (2003) Linezolid for the treatment of multidrug-resistant, gram-positive infections: experience from a compassionate-use program.. Clin Infect Dis, 36 (2): (159-68). [PMID:12522747] |
2. Chong-Fa Lai, Wei-Bin Xiao, Hua-Cheng Yan, Hui Yang, Lu-Xia Wang, Hui Guan, Qiu-ju Peng, Zhi-Rong Deng, Jian-Wen Chen, Lin-Kun An, Lei Shi. (2020) ZTW-41, a Potent Indolizinoquinoline-5,12-Dione Derivative Against Drug-Resistant Staphylococci and Enterococci Bacteria. Microbial Drug Resistance, 26 (2): (100-109). [PMID:31441704] |