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Linolenic acid - 99%, high purity , CAS No.463-40-1, Agonist of FFA1 receptor;Agonist of FFA4 receptor

Moligand™
≥99%

CAS#: 463-40-1
Formula: C₁₈H₃₀O₂
Molecular Weight: 278.44
Beilstein Registry Number: 2499
EC Number: MFCD00065720
MDL number: MFCD00065720
PubChem CID: 5280934

Item Number

L105575

Grouped product items
SKU	Size	Availability	Price
L105575-500mg	500mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$95.90
L105575-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$149.90
L105575-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$533.90

Basic Description

Synonyms	linolenic acid\|alpha-Linolenic acid\|463-40-1\|linolenate\|(9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid\|a-Linolenic acid\|cis,cis,cis-9,12,15-Octadecatrienoic acid\|all-cis-9,12,15-Octadecatrienoic acid\|(Z,Z,Z)-9,12,15-Octadecatrienoic acid\|9-cis,12-cis,15-cis-
Specifications & Purity	Moligand™, ≥99%
Biochemical and Physiological Mechanisms	An ω-3 fatty acid that serves as a precursor to eicosapentaenoic acid (EPA) but not docosahexaenoic acid. Conversion is greater in women than men, and conversely, β-oxidation metabolism is greater in men than women.
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of FFA1 receptor;Agonist of FFA4 receptor
Product Description	α-Linolenic Acid (ALA), an 18 carbon polyunsaturated essential fatty acid, has been found to exert in vitro anti-inflammatory effects in murine intestine. Mechanistic studies suggest that this compound decreases TNFα (tumor necrosis factor-α) secretion levels as well as NF-κB activation. Additionally, ALA has been noted to be a reactive oxygen species scavenger that temporarily improves cell proliferation. Further experiments report that an increase in ALA levels seems to be correlated inversely with plasma IL-6 (interleukin-6) soluble receptor levels.

Names and Identifiers

IUPAC Name	(9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid
INCHI	InChI=1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h3-4,6-7,9-10H,2,5,8,11-17H2,1H3,(H,19,20)/b4-3-,7-6-,10-9-
InChi Key	DTOSIQBPPRVQHS-PDBXOOCHSA-N
Canonical SMILES	CCC=CCC=CCC=CCCCCCCCC(=O)O
Isomeric SMILES	CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)O
WGK Germany	1
PubChem CID	5280934
Molecular Weight	278.44
Beilstein	2499

Certificates

Certificate of Analysis(COA)

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12 results found

Lot Number	Certificate Type	Date	Item
J2323639	Certificate of Analysis	Nov 08, 2023	L105575
J2323640	Certificate of Analysis	Nov 08, 2023	L105575
D23031001	Certificate of Analysis	Apr 09, 2023	L105575
D2303990	Certificate of Analysis	Apr 09, 2023	L105575
D2303989	Certificate of Analysis	Apr 08, 2023	L105575
J2210550	Certificate of Analysis	Oct 18, 2022	L105575
J2210551	Certificate of Analysis	Oct 18, 2022	L105575
J2210561	Certificate of Analysis	Oct 18, 2022	L105575
B2215815	Certificate of Analysis	Feb 17, 2022	L105575
B2215816	Certificate of Analysis	Feb 17, 2022	L105575
B2215829	Certificate of Analysis	Feb 17, 2022	L105575
B2215837	Certificate of Analysis	Feb 17, 2022	L105575

Chemical and Physical Properties

Sensitivity	Light sensitive.Air Sensitive
Refractive Index	1.48
Flash Point(°F)	235.4 °F
Flash Point(°C)	113 °C
Boil Point(°C)	230-232°C/1mmHg
Melt Point(°C)	-11°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Danger
Hazard Statements	H317:May cause an allergic skin reaction H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P284:[In case of inadequate ventilation] Wear respiratory protection. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately.
WGK Germany	1
Merck Index	5506

References

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