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Linomide - >96.0%(HPLC), high purity , CAS No.84088-42-6
Immunomodulator with antiangiogenic properties
Basic Description Synonyms ROQUINIMEX|Linomide|84088-42-6|LS-2616|FCF 89|LS 2616|4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide|FCF-89|N-phenyl-N-methyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-quinoline-3-carboxamide|DTXSID4045680|1,2-Dihydro-4-hydroxy-N,1-di Specifications & Purity ≥96%(HPLC) Biochemical and Physiological Mechanisms Immunomodulator with stimulatory and antitumor properties. Inhibitsin vivoapoptosis of T cells and inhibits angiogenesis in ratsin vivo. Shipped In Normal Product Description Linomide is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha.
Names and Identifiers IUPAC Name 4-hydroxy-N,1-dimethyl-2-oxo-N-phenylquinoline-3-carboxamide INCHI InChI=1S/C18H16N2O3/c1-19(12-8-4-3-5-9-12)17(22)15-16(21)13-10-6-7-11-14(13)20(2)18(15)23/h3-11,21H,1-2H3 InChi Key SGOOQMRIPALTEL-UHFFFAOYSA-N Canonical SMILES CN1C2=CC=CC=C2C(=C(C1=O)C(=O)N(C)C3=CC=CC=C3)O Isomeric SMILES CN1C2=CC=CC=C2C(=C(C1=O)C(=O)N(C)C3=CC=CC=C3)O PubChem CID 54676478 Molecular Weight 308.34
Chemical and Physical Properties Solubility Solvent:1.1eq. NaOH, Max Conc. mg/mL: 30.83, Max Conc. mM: 100 Melt Point(°C) 204 °C(dec.)
Safety and Hazards(GHS) Pictogram(s) GHS06 Signal Danger Hazard Statements H301: Toxic if swallowed
Precautionary Statements P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P301+P316: IF SWALLOWED: Get emergency medical help immediately.
Merck Index 8259
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C2023230