(±)-Lisofylline - ≥98%, high purity , CAS No.6493-06-7

  • ≥98%
Item Number
L274789
Grouped product items
SKUSizeAvailabilityPrice Qty
L274789-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$116.90

Anti-inflammatory agent.

Basic Description

SynonymsSB18959 | 1-(5-hydroxyhexyl)-3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione | Penthydroxifillyne | LSF | MFCD00871850 | NCGC00163298-01 | Pentoxifylline Alcohol | (R)-Lisophylline | Alcool metabolite, Pentoxifylline | AKOS037645541 | Penthydroxyfylli
Specifications & Purity≥98%
Biochemical and Physiological MechanismsAnti-inflammatory agent. Active metabolite of pentoxifylline and a potent inhibitor of phosphatidic acid formation (IC 50 = 0.6 mM). Decreases lipid peroxidation in vitro and in vivo. Suppresses proinflammatory cytokine expression.
Storage TempRoom temperature
Shipped InNormal
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at Room Temperature. The product can be stored for up to 12 months.

Associated Targets(Human)

HDAC6 Tclin Histone deacetylase 6 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
IMPA1 Tclin Inositol monophosphatase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 1-(5-hydroxyhexyl)-3,7-dimethylpurine-2,6-dione
INCHI InChI=1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3
InChi Key NSMXQKNUPPXBRG-UHFFFAOYSA-N
Canonical SMILES CC(CCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C)O
Isomeric SMILES CC(CCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C)O
PubChem CID 57782
Molecular Weight 280.3

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in DMSO to 25 mM

Related Documents

Solution Calculators