Lissamine rhodamine B - >98%(HPLC), high purity , CAS No.3520-42-1

  • ≥98%(HPLC)
Item Number
L109289
Grouped product items
SKUSizeAvailabilityPrice Qty
L109289-1g
1g
In stock
$12.90
L109289-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$37.90

Basic Description

SynonymsAizen Food Red No. 106 | CI 45100 | MS-24955 | NSC701554 | CI 45100 [INCI] | Acid red 52 | Acid Rhodamine B | Kiton Rhodamine B | MLVKMSCFQIQULM-UHFFFAOYSA-N | SMR000347999 | Ethanaminium, N-(6-(diethylamino)-9-(2,4-disulfophenyl)-3H-xanthen-3-ylidene)-N-
Specifications & Purity≥98%(HPLC)
Shipped InNormal
Product Description

Sulforhodamine B (SRB) is a bright-pink aminoxanthene dye. The sulforhodamine B (SRB) assay is extensively used for in vitro cytotoxicity screening. SRB binds to the protein constituents of the cells in a stoichiometric manner. Thus, the amount of dye extracted from stained cells is directly proportional to the cell mass. SRB can also be used for cell density determination.

Sulforhodamine B has been used as a dye in the MCF-7 (human breast adenocarcinoma cell line) cell proliferation assay

Associated Targets(Human)

CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLB Tchem DNA polymerase beta (23632 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FEN1 Tchem Flap endonuclease 1 (12055 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR2E3 Tchem Photoreceptor-specific nuclear receptor (502 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GNAS Tbio Guanine nucleotide-binding protein G(s), subunit alpha (103405 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SNCA Tchem Alpha-synuclein (10960 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TSG101 Tbio Tumor susceptibility gene 101 protein (2874 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP2 Tbio Ubiquitin carboxyl-terminal hydrolase 2 (8818 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BLM Tchem Bloom syndrome protein (4248 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EYA2 Tbio Eyes absent homolog 2 (5884 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KMT2A Tchem Histone-lysine N-methyltransferase MLL (17327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXFP1 Tchem Relaxin receptor 1 (6345 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MBNL1 Tbio Muscleblind-like protein 1 (34431 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATXN2 Tbio Ataxin-2 (54410 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAPGEF3 Tchem Rap guanine nucleotide exchange factor 3 (15528 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAPGEF4 Tchem Rap guanine nucleotide exchange factor 4 (11476 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 (239 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CGA Tbio Glycoprotein hormones alpha chain (29278 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
WRN Tbio Werner syndrome ATP-dependent helicase (8824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TARDBP Tchem TAR DNA-binding protein 43 (40113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NSD2 Tchem Histone-lysine N-methyltransferase NSD2 (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAN Tchem GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 (21853 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

blaZ Beta-lactamase (285 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Saccharomyces cerevisiae (19171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Genome polyprotein (620 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PYK Pyruvate kinase (6726 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
bla(tem-2) Beta Lactamase (819 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Phosphoglycerate kinase, glycosomal (2184 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
vpr Aberrant vpr protein (14595 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name sodium;4-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]benzene-1,3-disulfonate
INCHI InChI=1S/C27H30N2O7S2.Na/c1-5-28(6-2)18-9-12-21-24(15-18)36-25-16-19(29(7-3)8-4)10-13-22(25)27(21)23-14-11-20(37(30,31)32)17-26(23)38(33,34)35;/h9-17H,5-8H2,1-4H3,(H-,30,31,32,33,34,35);/q;+1/p-1
InChi Key SXQCTESRRZBPHJ-UHFFFAOYSA-M
Canonical SMILES CCN(CC)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](CC)CC)C=C3O2)C4=C(C=C(C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+]
Isomeric SMILES CCN(CC)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](CC)CC)C=C3O2)C4=C(C=C(C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+]
WGK Germany 2
RTECS BP6750000
PubChem CID 9916275
Molecular Weight 580.65
Beilstein 3886008

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
I2409119Certificate of AnalysisJun 22, 2024 L109289
I2409120Certificate of AnalysisJun 22, 2024 L109289
D2418354Certificate of AnalysisApr 13, 2024 L109289
D2418355Certificate of AnalysisApr 13, 2024 L109289
D2418401Certificate of AnalysisApr 13, 2024 L109289
D2418405Certificate of AnalysisApr 13, 2024 L109289
A2409055Certificate of AnalysisNov 23, 2023 L109289
K2330235Certificate of AnalysisNov 23, 2023 L109289

Safety and Hazards(GHS)

WGK Germany 2
RTECS BP6750000

Related Documents

Citations of This Product

1. Wenxuan Deng, Xin Xiang, Dongyun Chen, Najun Li, Qingfeng Xu, Hua Li, Jianmei Lu.  (2023)  A bifunctional heterostructured membrane for efficient emulsion separation and photocatalytic degradation of waterborne organic pollutants.  CHEMICAL ENGINEERING SCIENCE,  282  (1): (119344).  [PMID:19484123] [10.1016/j.ces.2023.119344]
2. Cui XiaoLing, Wang XiaoTan, Wen Jie, Li Xiao, Li Nan, Hao XuXiao, Zhao BaoXiang, Wu Xunwei, Miao JunYing.  (2022)  Identification of a new way to induce differentiation of dermal fibroblasts into vascular endothelial cells.  Stem Cell Research & Therapy,  13  (1): (1-16).  [PMID:36210433] [10.1186/s13287-022-03185-4]
3. Huang Yejing, Han Xiufen, Yu Xiao, Wang Shumei, Zhai Haiyun.  (2021)  Capillary Electrophoresis-Indirect Laser-Induced Fluorescence Detection of Neomycin in Fish.  CHROMATOGRAPHIA,  84  (9): (861-868).  [PMID:] [10.1007/s10337-021-04075-2]
4. Shuai Zhang, Cong Zhang, Xiaodong Shao, Rentian Guan, Yingying Hu, Keying Zhang, Wenjing Liu, Min Hong, Qiaoli Yue.  (2021)  Dual-emission ratio fluorescence for selective and sensitive detection of ferric ions and ascorbic acid based on one-pot synthesis of glutathione protected gold nanoclusters.  RSC Advances,  11  (28): (17283-17290).  [PMID:35479669] [10.1039/D0RA10281D]
5. Hu Yingying, Guan Rentian, Shao Xiaodong, Zhang Cong, Fan Xiaoyu, Zhang Shuai, Hong Min, Yue Qiaoli.  (2020)  Synthesis of Carbon Dots by Varying Doped Elements and Application in Serine Detection.  JOURNAL OF FLUORESCENCE,  30  (6): (1447-1456).  [PMID:32780262] [10.1007/s10895-020-02592-1]
6. Yingying Hu, Rentian Guan, Cong Zhang, Keying Zhang, Wenjing Liu, Xiaodong Shao, Qingwang Xue, Qiaoli Yue.  (2020)  Fluorescence and photocatalytic activity of metal-free nitrogen-doped carbon quantum dots with varying nitrogen contents.  APPLIED SURFACE SCIENCE,  531  (147344).  [PMID:] [10.1016/j.apsusc.2020.147344]
7. Hao Zhang, Min Lu, Hui Jiang, Xu Wang, Feng-Qing Yang.  (2020)  Evaluation inhibitory activity of catechins on trypsin by capillary electrophoresis–based immobilized enzyme microreactor with chromogenic substrate.  JOURNAL OF SEPARATION SCIENCE,  43  (15): (3136-3145).  [PMID:32515904] [10.1002/jssc.202000132]
8. Qiaoyun Qi, Yanru Li, Wu Qiu, Wenhai Zhang, Chenyang Shi, Chen Hou, Wen Yan, Jiani Huang, Likun Yang, Hao Wang, Wenxi Guo, Xiang Yang Liu, Naibo Lin.  (2019)  Transient bioelectrical devices inspired by a silkworm moth breaking out of its cocoon.  RSC Advances,  (25): (14254-14259).  [PMID:35519322] [10.1039/C9RA02147G]
9. Jing Gao, Miyu Zhang, Jingtao Wang, Guanhua Liu, Hengrao Liu, Yanjun Jiang.  (2019)  Bioinspired Modification of Layer-Stacked Molybdenum Disulfide (MoS2) Membranes for Enhanced Nanofiltration Performance.  ACS Omega,  (2): (4012–4022).  [PMID:31459610] [10.1021/acsomega.9b00155]
10. Zhengjun Cheng, Lei Zhang, Xiao Guo, Xiaohui Jiang, Rong Liu.  (2015)  Removal of Lissamine rhodamine B and acid orange 10 from aqueous solution using activated carbon/surfactant: Process optimization, kinetics and equilibrium.  Journal of the Taiwan Institute of Chemical Engineers,  47  (149).  [PMID:] [10.1016/j.jtice.2014.09.032]
11. Shuo-Hui Cao, Zhe-Xiang Zou, Yu-Hua Weng, Wei-Peng Cai, Qian Liu, Yao-Qun Li.  (2014)  Plasmon-mediated fluorescence with distance independence: From model to a biosensing application.  BIOSENSORS & BIOELECTRONICS,  58  (258).  [PMID:24657646] [10.1016/j.bios.2014.02.067]
12. Xiuying Liu, Bing Bai, Qian Zhou, Yingchao Yu, Shujuan Ji.  (2013)  Grafting of Molecularly Imprinted Polymers on to Carboxyl-Modified Multiwalled Carbon Nanotubes for the Extraction of Rhodamine B from Dried Chili Powder.  ANALYTICAL LETTERS,      [PMID:] [10.1080/00032719.2013.803252]

References

1. Wenxuan Deng, Xin Xiang, Dongyun Chen, Najun Li, Qingfeng Xu, Hua Li, Jianmei Lu.  (2023)  A bifunctional heterostructured membrane for efficient emulsion separation and photocatalytic degradation of waterborne organic pollutants.  CHEMICAL ENGINEERING SCIENCE,  282  (1): (119344).  [PMID:19484123] [10.1016/j.ces.2023.119344]
2. Cui XiaoLing, Wang XiaoTan, Wen Jie, Li Xiao, Li Nan, Hao XuXiao, Zhao BaoXiang, Wu Xunwei, Miao JunYing.  (2022)  Identification of a new way to induce differentiation of dermal fibroblasts into vascular endothelial cells.  Stem Cell Research & Therapy,  13  (1): (1-16).  [PMID:36210433] [10.1186/s13287-022-03185-4]
3. Huang Yejing, Han Xiufen, Yu Xiao, Wang Shumei, Zhai Haiyun.  (2021)  Capillary Electrophoresis-Indirect Laser-Induced Fluorescence Detection of Neomycin in Fish.  CHROMATOGRAPHIA,  84  (9): (861-868).  [PMID:] [10.1007/s10337-021-04075-2]
4. Shuai Zhang, Cong Zhang, Xiaodong Shao, Rentian Guan, Yingying Hu, Keying Zhang, Wenjing Liu, Min Hong, Qiaoli Yue.  (2021)  Dual-emission ratio fluorescence for selective and sensitive detection of ferric ions and ascorbic acid based on one-pot synthesis of glutathione protected gold nanoclusters.  RSC Advances,  11  (28): (17283-17290).  [PMID:35479669] [10.1039/D0RA10281D]
5. Hu Yingying, Guan Rentian, Shao Xiaodong, Zhang Cong, Fan Xiaoyu, Zhang Shuai, Hong Min, Yue Qiaoli.  (2020)  Synthesis of Carbon Dots by Varying Doped Elements and Application in Serine Detection.  JOURNAL OF FLUORESCENCE,  30  (6): (1447-1456).  [PMID:32780262] [10.1007/s10895-020-02592-1]
6. Yingying Hu, Rentian Guan, Cong Zhang, Keying Zhang, Wenjing Liu, Xiaodong Shao, Qingwang Xue, Qiaoli Yue.  (2020)  Fluorescence and photocatalytic activity of metal-free nitrogen-doped carbon quantum dots with varying nitrogen contents.  APPLIED SURFACE SCIENCE,  531  (147344).  [PMID:] [10.1016/j.apsusc.2020.147344]
7. Hao Zhang, Min Lu, Hui Jiang, Xu Wang, Feng-Qing Yang.  (2020)  Evaluation inhibitory activity of catechins on trypsin by capillary electrophoresis–based immobilized enzyme microreactor with chromogenic substrate.  JOURNAL OF SEPARATION SCIENCE,  43  (15): (3136-3145).  [PMID:32515904] [10.1002/jssc.202000132]
8. Qiaoyun Qi, Yanru Li, Wu Qiu, Wenhai Zhang, Chenyang Shi, Chen Hou, Wen Yan, Jiani Huang, Likun Yang, Hao Wang, Wenxi Guo, Xiang Yang Liu, Naibo Lin.  (2019)  Transient bioelectrical devices inspired by a silkworm moth breaking out of its cocoon.  RSC Advances,  (25): (14254-14259).  [PMID:35519322] [10.1039/C9RA02147G]
9. Jing Gao, Miyu Zhang, Jingtao Wang, Guanhua Liu, Hengrao Liu, Yanjun Jiang.  (2019)  Bioinspired Modification of Layer-Stacked Molybdenum Disulfide (MoS2) Membranes for Enhanced Nanofiltration Performance.  ACS Omega,  (2): (4012–4022).  [PMID:31459610] [10.1021/acsomega.9b00155]
10. Zhengjun Cheng, Lei Zhang, Xiao Guo, Xiaohui Jiang, Rong Liu.  (2015)  Removal of Lissamine rhodamine B and acid orange 10 from aqueous solution using activated carbon/surfactant: Process optimization, kinetics and equilibrium.  Journal of the Taiwan Institute of Chemical Engineers,  47  (149).  [PMID:] [10.1016/j.jtice.2014.09.032]
11. Shuo-Hui Cao, Zhe-Xiang Zou, Yu-Hua Weng, Wei-Peng Cai, Qian Liu, Yao-Qun Li.  (2014)  Plasmon-mediated fluorescence with distance independence: From model to a biosensing application.  BIOSENSORS & BIOELECTRONICS,  58  (258).  [PMID:24657646] [10.1016/j.bios.2014.02.067]
12. Xiuying Liu, Bing Bai, Qian Zhou, Yingchao Yu, Shujuan Ji.  (2013)  Grafting of Molecularly Imprinted Polymers on to Carboxyl-Modified Multiwalled Carbon Nanotubes for the Extraction of Rhodamine B from Dried Chili Powder.  ANALYTICAL LETTERS,      [PMID:] [10.1080/00032719.2013.803252]

Solution Calculators