Lithium chloride - ACS reagent,≥99%, high purity , CAS No.7447-41-8

Item Number

L116328

• Synonyms: CCRIS 5924 | HSDB 4281 | Lithium chloride, puriss. p.a., ACS reagent, anhydrous, >=99.0% (AT) | NCGC00093980-01 | (2R)-2-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-3-naphthalen-2-ylpropanoic acid | (S)-N-(9-FLUORENYLMETHOXYCARBONYL)-2-AMINO-4-PENTYNOIC ACI
• Specifications & Purity: ACS, ≥99%
• Storage Temp: Argon charged
• Shipped In: Normal
• Grade: ACS

Product Description

Lithium chloride (LiCl) is a lithium salt. In chemical synthesis, it is used as a source of chlorine nucleophiles as well as a source of chlorine ligands. LiCl is also used as a desiccant in dry air streams.

Application：

Lithium chloride can be used as: A source of chloride anion for the conversion of alcohols to alkyl chloride under Mitsunobu conditions. An additive in the palladium-catalyzed coupling and carbonylative coupling reactions of organostannanes and vinyl triflates. A reagent for the cleavage of protecting groups under mild conditions. It readily converts acetals and ketals to the corresponding carbonyl compounds. A reagent in the dehydrohalogenation of α-halocarbonyl compounds to α,β-unsaturated carbonyls compound in the presence of DMF. LiCl is also used with other reagents: LiCl:DIPEA (1:1 molar ratio) is used in Horner–Wadsworth–Emmons alkenation reaction. LiCl:Hexamethylphosphoric triamide is used in decarboxylative alkylation and chloride displacement reactions. LiCl is used as an additive in solid-phase peptide synthesis because it increases resin swelling and improves the efficiencies of complex coupling steps.