liver FABP Mouse mAb - Primary antibody, specific to liver FABP, Mouse IgG2b
Synonyms
Fatty acid-binding protein 1 | L-FABP | Liver-type fatty acid-binding protein | FABP1 | FABPL | fatty acid binding protein 1, liver | fatty acid-binding protein, liver | LFABP | L-FABP | L-FABPFatty acid-binding protein 1 | Liver-type fatty acid-binding p
Specifications & Purity
Carrier Free, ExactAb™, Validated, High Performance, See COA
Host species
Mouse
Specificity
liver FABP
Immunogen
Recombinant FABP1 expressed in E.coli (AA 2-127)
Positive Control
WB: Mouse liver and Hep G2 lysates.
Conjugation
Unconjugated
Grade
Carrier Free, ExactAb™, High Performance, Validated
Product Description
Mouse anti Human liver FABP Antibody, Monoclonal (1#), could be used for WB and so on. Application WB: 0.01-5 µg/mL Protein Function Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
Product Properties
Isotype
Mouse IgG2b
Light Chain Type
kappa
SDS-PAGE
150 kDa
Purification Method
Protein A + Protein G purified
Form
Liquid
Concentration
See COA
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Images
liver FABP Mouse mAb (Ab113311) - Western Blot All lanes: liver FABP Mouse mAb (Ab113311) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/40000 dilution
Predicted band size: 14 kDa Observed band size: 14 kDa Exposure time: 15.7 s
1.Hertzel AV, Hellberg K, Reynolds JM, Kruse AC, Juhlmann BE, Smith AJ, Sanders MA, Ohlendorf DH, Suttles J, Bernlohr DA. (2009) Identification and characterization of a small molecule inhibitor of Fatty Acid binding proteins.. J Med Chem, 52 (19):(6024-31). [PMID:19754198][10.1021/op500134e]
2.Gregory G Martin,Avery L McIntosh,Huan Huang,Shipra Gupta,Barbara P Atshaves,Kerstin K Landrock,Danilo Landrock,Ann B Kier,Friedhelm Schroeder. (2013-12-05) The human liver fatty acid binding protein T94A variant alters the structure, stability, and interaction with fibrates.. Biochemistry, 52 ((51)):(9347-9357). [PMID:24299557]
3.Zhou Y, Nie T, Zhang Y, Song M, Li K, Ding M, Ding K, Wu D, Xu Y.. (2016) The discovery of novel and selective fatty acid binding protein 4 inhibitors by virtual screening and biological evaluation.. Bioorg Med Chem, 24 (18):(4310-4317). [PMID:27460668][10.1016/j.bmc.2016.07.022]
4.Hendrick AG, Müller I, Willems H, Leonard PM, Irving S, Davenport R, Ito T, Reeves J, Wright S, Allen V, Wilkinson S, Heffron H, Bazin R, Turney J, Mitchell PJ.. (2016) Identification and Investigation of Novel Binding Fragments in the Fatty Acid Binding Protein 6 (FABP6).. J Med Chem, 59 (17):(8094-8102). [PMID:27500412][10.1021/acs.jmedchem.6b00869]
5.Chan, L L and 7 more authors.. (1985) Human liver fatty acid binding protein cDNA and amino acid sequence. Functional and evolutionary implications.. The Journal of biological chemistry, (10):[PMID:3838309]
6.Lowe, J B JB and 5 more authors.. (1985) Human liver fatty acid binding protein. Isolation of a full length cDNA and comparative sequence analyses of orthologous and paralogous proteins.. The Journal of biological chemistry, (25):[PMID:3838313]
7.Huang, Huan H and 9 more authors.. (2015) Human FABP1 T94A variant enhances cholesterol uptake.. Biochimica et biophysica acta, [PMID:25732850]
8.Thomas R Burkard,Melanie Planyavsky,Ines Kaupe,Florian P Breitwieser,Tilmann Bürckstümmer,Keiryn L Bennett,Giulio Superti-Furga,Jacques Colinge. (2011-01-29) Initial characterization of the human central proteome.. BMC systems biology, 5 (17-17). [PMID:21269460]
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