LNT 1 - ≥98%(HPLC), high purity , CAS No.824983-91-7

  • ≥98%(HPLC)
Item Number
L288189
Grouped product items
SKUSizeAvailabilityPrice Qty
L288189-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$58.90
L288189-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$265.90
L288189-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$286.90
L288189-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$645.90

Potent flap endonuclease 1 (FEN1) inhibitor; induces DNA damage response

Basic Description

Specifications & Purity≥98%(HPLC)
Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

ERCC5 Tchem DNA repair protein complementing XP-G cells (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
FEN1 Tchem Flap endonuclease 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
T-24 (2342 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FEN1 Tchem Flap endonuclease 1 (12055 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 1-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-3-hydroxythieno[3,2-d]pyrimidine-2,4-dione
INCHI InChI=1S/C15H12N2O5S/c18-14-13-10(5-6-23-13)16(15(19)17(14)20)7-9-8-21-11-3-1-2-4-12(11)22-9/h1-6,9,20H,7-8H2
InChi Key MXQGCMQXTPTJJT-UHFFFAOYSA-N
Canonical SMILES C1C(OC2=CC=CC=C2O1)CN3C4=C(C(=O)N(C3=O)O)SC=C4
Isomeric SMILES C1C(OC2=CC=CC=C2O1)CN3C4=C(C(=O)N(C3=O)O)SC=C4
PubChem CID 11652865
Molecular Weight 332.33

Certificates

Certificate of Analysis(COA)

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5 results found

Lot NumberCertificate TypeDateItem
L2411204Certificate of AnalysisDec 18, 2024 L288189
J2116194Certificate of AnalysisJul 12, 2024 L288189
J2116195Certificate of AnalysisJul 12, 2024 L288189
J2116217Certificate of AnalysisJul 12, 2024 L288189
J2116219Certificate of AnalysisJul 12, 2024 L288189

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 16.62, Max Conc. mM: 50

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

Related Documents

Solution Calculators