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Lomerizine Dihydrochloride - >98%, high purity , CAS No.101477-54-7

  • ≥98%
Item Number
L157774
Grouped product items
SKUSizeAvailabilityPrice Qty
L157774-50mg
50mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$68.90
L157774-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$310.90
L157774-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,117.90

Ca 2+ channel blocker

Basic Description

Synonyms101477-54-7, 101477-55-8(free base) | Tox21_112172 | Lomerizine Dihydrochloride, 98% | Terranas (TN) | CS-0012057 | DTXCID9026427 | s1082 | BCP12061 | LOMERIZINE 2HCL | NCGC00164543-02 | FT-0627971 | D02633 | NCGC00164543-01 | Q27258118 | 1-(2,3,4-Trimeth
Specifications & Purity≥98%
Biochemical and Physiological MechanismsCa 2+ channel blocker. Inhibits voltage-activated inward calcium currents. Shows vasodilatory and neuroprotective effects against ischemic injury in vivo . Orally active.
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(non-human)

Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine;dihydrochloride
INCHI InChI=1S/C27H30F2N2O3.2ClH/c1-32-24-13-8-21(26(33-2)27(24)34-3)18-30-14-16-31(17-15-30)25(19-4-9-22(28)10-5-19)20-6-11-23(29)12-7-20;;/h4-13,25H,14-18H2,1-3H3;2*1H
InChi Key LOGVKVSFYBBUAJ-UHFFFAOYSA-N
Canonical SMILES COC1=C(C(=C(C=C1)CN2CCN(CC2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)OC)OC.Cl.Cl
Isomeric SMILES COC1=C(C(=C(C=C1)CN2CCN(CC2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)OC)OC.Cl.Cl
WGK Germany 3
RTECS TK9189000
PubChem CID 122125
Molecular Weight 541.46

Certificates

C of A & Other Certificates(BSE/TSE, COO)

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
I2201624Certificate of AnalysisJun 15, 2022 L157774
I2201761Certificate of AnalysisJun 15, 2022 L157774
I2201762Certificate of AnalysisJun 15, 2022 L157774

Chemical and Physical Properties

Solubility≥ 24.1mg/mL in DMSO with gentle warming
SensitivityHygroscopic,Heat Sensitive
Melt Point(°C)180 °C(dec.)

Safety and Hazards(GHS)

Pictogram(s) GHS09,   GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

H400:Very toxic to aquatic life

H410:Very toxic to aquatic life with long lasting effects

Precautionary Statements

P273:Avoid release to the environment.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P391:Collect spillage.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

WGK Germany 3
RTECS TK9189000
Merck Index 5563

Related Documents

Solution Calculators