Losartan Carboxaldehyde , CAS No.114798-36-6

Item Number
L335415
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L335415-10mg
10mg
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a metabolite of Losartan and an intermediate in synthesis of the EXP 3174

Basic Description

Synonyms2-Butyl-4-chloro-1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-imidazol-5-carbaldehyde | Losartan Carboxaldehyde | Losartan EP Impurity K | CS-0064690 | Losartan carboxaldehyde [EXP3179] | AS-74776 | HY-114950 | 1H-Imidazole-5-carboxaldehyde, 2-butyl-
Storage TempStore at 2-8°C
Shipped InWet ice

Associated Targets(Human)

AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Agtr1b Angiotensin II receptor (1735 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carbaldehyde
INCHI InChI=1S/C22H21ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,14H,2-3,8,13H2,1H3,(H,25,26,27,28)
InChi Key FQZSMTSTFMNWQF-UHFFFAOYSA-N
Canonical SMILES CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C=O)Cl
Isomeric SMILES CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C=O)Cl
PubChem CID 9802264
Molecular Weight 420.89

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in Chloroform, Dimethyl Formamide, Dimethyl Sulfoxide, Ethanol and Methanol
Melt Point(°C)84-86° C

Related Documents

Solution Calculators