Loxoprofen sodium - ≥98%, high purity , CAS No.80382-23-6

  • ≥98%
Item Number
L338874
Grouped product items
SKUSizeAvailabilityPrice Qty
L338874-1g
1g
In stock
$285.90
L338874-5g
5g
In stock
$1,282.90
L338874-25g
25g
In stock
$5,771.90
L338874-100g
100g
In stock
$20,776.90

Basic Description

SynonymsBL164648 | Loxoprofen sodium | CCG-101024 | CS-0013894 | Q-201325 | AKOS015994737 | Naptalam, analytical standard | LOXOPROFEN SODIUM HYDRATE [JAN] | UNII-NDC2M7399S | WORCCYVLMMTGFR-UHFFFAOYSA-M | N-((Trichloromethyl)mercapto)-4-cyclohexene-1,2-dicarboxi
Specifications & Purity≥98%
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
Product Description

Product Application
Loxoprofen sodium is a non-steroidal anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen sodium is a nonselective COX inhibitor with IC50s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively.

Associated Targets(Human)

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAN Tchem GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 (21853 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cavia porcellus (23802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488200382
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488200382
IUPAC Name sodium;2-[4-[(2-oxocyclopentyl)methyl]phenyl]propanoate
INCHI InChI=1S/C15H18O3.Na/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16;/h5-8,10,13H,2-4,9H2,1H3,(H,17,18);/q;+1/p-1
InChi Key WORCCYVLMMTGFR-UHFFFAOYSA-M
Canonical SMILES CC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)[O-].[Na+]
Isomeric SMILES CC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)[O-].[Na+]
PubChem CID 23663407
UN Number 2811
Packing Group III
Molecular Weight 268.286

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
C23171032Certificate of AnalysisMar 07, 2023 L338874
C2317865Certificate of AnalysisMar 07, 2023 L338874
C2317876Certificate of AnalysisMar 07, 2023 L338874
C2317883Certificate of AnalysisMar 07, 2023 L338874
C2317904Certificate of AnalysisMar 07, 2023 L338874
C2317915Certificate of AnalysisMar 07, 2023 L338874
C2317938Certificate of AnalysisMar 07, 2023 L338874
C2317940Certificate of AnalysisMar 07, 2023 L338874

Chemical and Physical Properties

Melt Point(°C)202~206° C

Safety and Hazards(GHS)

Pictogram(s) GHS06
Signal Danger
Hazard Statements

H301:Toxic if swallowed

Precautionary Statements

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P301+P310+P330:IF SWALLOWED: Rinse mouth.Immediately call a POISON CENTER/doctor/.

Class 6.1

Related Documents

Citations of This Product

1. Meng Yan, Li Zhu, Shuai Wu, Yu Cao, Nianlian Mou, Qingjia Chi, Guixue Wang, Yuan Zhong, Wei Wu.  (2022)  ROS responsive polydopamine nanoparticles to relieve oxidative stress and inflammation for ameliorating acute inflammatory bowel.  Biomaterials Advances,  142  (213126).  [PMID:36191534] [10.1016/j.bioadv.2022.213126]

References

1. Meng Yan, Li Zhu, Shuai Wu, Yu Cao, Nianlian Mou, Qingjia Chi, Guixue Wang, Yuan Zhong, Wei Wu.  (2022)  ROS responsive polydopamine nanoparticles to relieve oxidative stress and inflammation for ameliorating acute inflammatory bowel.  Biomaterials Advances,  142  (213126).  [PMID:36191534] [10.1016/j.bioadv.2022.213126]

Solution Calculators