Loxoprofen sodium - 10mM in Water, high purity , CAS No.80382-23-6

  • 10mM in Water
Item Number
L426080
Grouped product items
SKUSizeAvailabilityPrice Qty
L426080-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$69.90

Basic Description

SynonymsLoxoprofen sodium | 80382-23-6 | Loxoprofen sodium salt | Sodium 2-(4-((2-oxocyclopentyl)methyl)phenyl)propanoate | CS-600 | Loxoprofen (sodium) | Loxoprofen sodium hydrate | sodium loxoprofen | LX-A | NDC2M7399S | CHEBI:76198 | MFCD00941425 | sodium;2-[4-[(2-oxocyclopentyl)meth
Specifications & Purity10mM in Water
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Product Application
Loxoprofen sodium is a non-steroidal anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen sodium is a nonselective COX inhibitor with IC50s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively.

Associated Targets(Human)

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAN Tchem GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 (21853 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cavia porcellus (23802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name sodium;2-[4-[(2-oxocyclopentyl)methyl]phenyl]propanoate
INCHI InChI=1S/C15H18O3.Na/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16;/h5-8,10,13H,2-4,9H2,1H3,(H,17,18);/q;+1/p-1
InChi Key WORCCYVLMMTGFR-UHFFFAOYSA-M
Canonical SMILES CC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)[O-].[Na+]
Isomeric SMILES CC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)[O-].[Na+]
PubChem CID 23663407
UN Number 2811
Packing Group III
Molecular Weight 268.286

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Melt Point(°C)202~206° C

Safety and Hazards(GHS)

Pictogram(s) GHS06
Signal Danger
Hazard Statements

H301:Toxic if swallowed

Precautionary Statements

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P301+P310+P330:IF SWALLOWED: Rinse mouth.Immediately call a POISON CENTER/doctor/.

Class 6.1

Related Documents

Citations of This Product

1. Meng Yan, Li Zhu, Shuai Wu, Yu Cao, Nianlian Mou, Qingjia Chi, Guixue Wang, Yuan Zhong, Wei Wu.  (2022)  ROS responsive polydopamine nanoparticles to relieve oxidative stress and inflammation for ameliorating acute inflammatory bowel.  Biomaterials Advances,  142  (213126).  [PMID:36191534] [10.1016/j.bioadv.2022.213126]

References

1. Meng Yan, Li Zhu, Shuai Wu, Yu Cao, Nianlian Mou, Qingjia Chi, Guixue Wang, Yuan Zhong, Wei Wu.  (2022)  ROS responsive polydopamine nanoparticles to relieve oxidative stress and inflammation for ameliorating acute inflammatory bowel.  Biomaterials Advances,  142  (213126).  [PMID:36191534] [10.1016/j.bioadv.2022.213126]

Solution Calculators