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SKU | Size | Availability | Price | Qty |
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L288774-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $839.90 |
Potent NPY Y5receptor antagonist
Synonyms | SCHEMBL14528347 | N-[[trans-4-[(4,5-Dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]methanesulfonamide | N-[[trans-4-[(4,5-dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]-methanesulfonamide | Q6694803 | NCGC00370875- |
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Specifications & Purity | ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | LU AA33810 is a potent neuropeptide Y (NPY) Y5 receptor antagonist (Ki = 1.5 nM in vitro). Displays ≥ 3300-fold affinity for Y5 over Y1, Y2 and Y4 receptors. Also binds human 5-HT2B and 5-HT1A receptors (Ki values are 247 and 478 nM respectively). Exerts |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | N-[[4-(4,5-dihydro-[1]benzothiepino[5,4-d][1,3]thiazol-2-ylamino)cyclohexyl]methyl]methanesulfonamide |
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INCHI | InChI=1S/C19H25N3O2S3/c1-27(23,24)20-12-13-6-8-14(9-7-13)21-19-22-18-15-4-2-3-5-16(15)25-11-10-17(18)26-19/h2-5,13-14,20H,6-12H2,1H3,(H,21,22) |
InChi Key | UWSBTSAJZMIHBL-UHFFFAOYSA-N |
Canonical SMILES | CS(=O)(=O)NCC1CCC(CC1)NC2=NC3=C(S2)CCSC4=CC=CC=C43 |
Isomeric SMILES | CS(=O)(=O)NCC1CCC(CC1)NC2=NC3=C(S2)CCSC4=CC=CC=C43 |
PubChem CID | 22254068 |
Molecular Weight | 423.62 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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D2403319 | Certificate of Analysis | Mar 14, 2024 | L288774 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 42.36, Max Conc. mM: 100 |
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