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LUF 6283 - ≥98%(HPLC), high purity , CAS No.92933-48-7, Agonist of HCA 2 receptor

Moligand™

≥98%(HPLC)

CAS#: 92933-48-7
Formula: C₈H₁₂N₂O₂
Molecular Weight: 168.19
PubChem CID: 6485181

Item Number

L287351

Grouped product items
SKU	Size	Availability	Price
L287351-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$399.90
L287351-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$99.90
L287351-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$999.90
L287351-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$422.90

HCA2(GPR109A) partial agonist

View related series

GPCR/G Protein HCA2 receptor Agonist

Basic Description

Synonyms	5-Butyl-2H-pyrazole-3-carboxylic acid \| BDBM50220842 \| AKOS000301963 \| LUF6283;LUF-6283 \| BBL030719 \| ZJTXSGLJNBAMJS-UHFFFAOYSA-N \| 3-butyl-1H-pyrazole-5-carboxylicacid \| VS-09994 \| LUF 6283 \| EN300-237993 \| 1H-Pyrazole-3-carboxylic acid, 5-butyl- \| SCHEM
Specifications & Purity	Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms	Partial agonist of hydroxycarboxylic acid receptor 2 (HCA2) (Ki= 0.55μM). Thought to lower plasma very-low-density lipoprotein (VLDL)-triglyceride levels by affecting hepatic VLDL production in normolipidemic C57BL/6 mice.
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of HCA 2 receptor

Associated Targets(Human)

HCAR2 Tclin Hydroxycarboxylic acid receptor 2 (2 Activities)

Discover Target: HCAR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HCAR3 Tchem HM74 nicotinic acid GPCR (353 Activities)

Discover Target: HCAR3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hcar2 Hydroxycarboxylic acid receptor 2 (55 Activities)

Discover Target: Hcar2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	5-butyl-1H-pyrazole-3-carboxylic acid
INCHI	InChI=1S/C8H12N2O2/c1-2-3-4-6-5-7(8(11)12)10-9-6/h5H,2-4H2,1H3,(H,9,10)(H,11,12)
InChi Key	ZJTXSGLJNBAMJS-UHFFFAOYSA-N
Canonical SMILES	CCCCC1=CC(=NN1)C(=O)O
Isomeric SMILES	CCCCC1=CC(=NN1)C(=O)O
Alternate CAS	92933-48-7
PubChem CID	6485181
MeSH Entry Terms	LUF6283
Molecular Weight	168.19

Certificates

Certificate of Analysis(COA)

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8 results found

Lot Number	Certificate Type	Date	Item
L2315113	Certificate of Analysis	Dec 02, 2023	L287351
L2315114	Certificate of Analysis	Dec 02, 2023	L287351
L2315115	Certificate of Analysis	Dec 02, 2023	L287351
L2315116	Certificate of Analysis	Dec 02, 2023	L287351
L2315117	Certificate of Analysis	Dec 02, 2023	L287351
L2315118	Certificate of Analysis	Dec 02, 2023	L287351
L2315119	Certificate of Analysis	Dec 02, 2023	L287351
L2315120	Certificate of Analysis	Dec 02, 2023	L287351

Solubility

Solvent:DMSO, Max Conc. mg/mL: 16.82, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 16.82, Max Conc. mM: 100

Sensitivity

Moisture sensitive

Safety and Hazards(GHS)

Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

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