Lusianthridin - ≥98.0%, high purity , CAS No.87530-30-1

  • ≥98%
Item Number
L651857
Grouped product items
SKUSizeAvailabilityPrice Qty
L651857-1mg
1mg
Available within 8-12 weeks(?)
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$320.90

Phenols Polyphenols Others

Basic Description

SynonymsDTXSID50331917 | BDBM246496 | 2,5-Dihydroxy-7-methoxy-9,10-dihydrophenanthrene (14) | CHEBI:28678 | FS-7984 | 4,7-Dihydroxy-2-methoxy-9,10-dihydrophenanthrene | SCHEMBL4743850 | 7-methoxy-9,10-dihydrophenanthrene-2,5-diol | Q27103833 | HY-121418 | Lusiant
Specifications & Purity≥98%
Biochemical and Physiological MechanismsLusianthridin, a pure compound from Dendrobium venustum , have an anti-migratory effect. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signaling.
Storage TempProtected from light,Store at -80°C
Shipped InIce chest + Ice pads
Product Description

Lusianthridin, a pure compound from Dendrobium venustum , have an anti-migratory effect. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signaling.

In Vitro

Lusianthridin (0-100 μM) inhibits cell viability at concentrations greater than 50 μM in both H460 and H292 cells. Lusianthridin significantly reduces the CSC populations in both H460 and H292 cells of the CSC spheres, with a significant decrease in the size of the H460 CSC spheres by approximately 10%, 63%, and 77% at day 3 at concentration 5, 10, and 20 μM Lusianthridin, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: The human non-small cell lung cancer cell lines, NCI-H460, and NCI-H292 cells.\n0-100 μM. Concentration: 0-100 μM. Incubation Time: 24 h. Result: Caused a significant reduction in terms of cell viability at concentrations greater than 50 μM in both H460 and H292 cells.

Form:Solid

Associated Targets(Human)

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

RAW264.7 (28094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ileum (29 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Colletotrichum truncatum (198 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 7-methoxy-9,10-dihydrophenanthrene-2,5-diol
INCHI InChI=1S/C15H14O3/c1-18-12-7-10-3-2-9-6-11(16)4-5-13(9)15(10)14(17)8-12/h4-8,16-17H,2-3H2,1H3
InChi Key RDKDIPDDUFMMMT-UHFFFAOYSA-N
Canonical SMILES COC1=CC2=C(C3=C(CC2)C=C(C=C3)O)C(=C1)O
Isomeric SMILES COC1=CC2=C(C3=C(CC2)C=C(C=C3)O)C(=C1)O
Alternate CAS 87530-30-1
PubChem CID 442702
MeSH Entry Terms 4,7-dihydroxy-2-methoxy-9,10-dihydrophenanthrene;lusianthridin
Molecular Weight 242.27

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