Luteolin - ≥98%(HPLC), high purity , CAS No.491-70-3

59 Citations
Item Number
L107329
Grouped product items
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L107329-250mg
250mg
In stock
$37.90
L107329-500mg
500mg
In stock
$64.90
L107329-1g
1g
In stock
$108.90
L107329-5g
5g
In stock
$423.90
L107329-25g
25g
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$1,299.90
L107329-100g
100g
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$3,699.90

Anti-inflammatory, antioxidant and free radical scavenger

Basic Description

Synonyms4dew | Cyanidenon 1470 | HMS3561N09 | 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one | C.I. Natural Yellow 2 | LUTEOLIN [WHO-DD] | BIDD:ER0122 | Flacitran | Luteolin, >=98% (TLC), powder | Luteolol | MLS006011917 | CCRIS 3790 | BCP9000865 | HMS335
Specifications & PurityMoligand™, ≥98%(HPLC)
Biochemical and Physiological MechanismsAnti-inflammatory, antioxidant and free radical scavenger. Inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 activation. Also inhibits TNF-α-induced COX-2 expression. Antiproliferative and chemopreventative;
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™
Note250mg售完停产
Product Description

Luteolin is an antioxidant flavonoid and a free radical scavenger. It inhibits rat liver cytosolic glutathione S-transferase activity and soybean and reticulocyte 15-LO (15-lipoxygenases). Luteolin also shows cytotoxic effects on Raji lymphoma cells. Incubation of the non-tumor cell line C3H10T?CL8 with luteolin results in induction of p53 accumulation and apoptosis, with apoptosis occurring at the G2/M phase of the cell cycle. Luteolin is an inhibitor of Cot, PDE1-5, c-Src, HDAC, Maltase-glucoamylase, Topo I, PKC ε, Fatty Acid Synthase, PPAR γ and MMP.
An inhibitor of glutathione S-transferase and 15-LO.

Associated Targets(Human)

CYP1A2 Tchem Cytochrome P450 1A2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP1B1 Tchem Cytochrome P450 1B1 (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DPP4 Tclin Dipeptidyl peptidase 4 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TTR Tclin Transthyretin (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP12 Tchem Macrophage metalloelastase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA4 Tclin Carbonic anhydrase 4 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA12 Tclin Carbonic anhydrase 12 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA7 Tclin Carbonic anhydrase 7 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP1A1 Tchem Cytochrome P450 1A1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
XDH Tclin Xanthine dehydrogenase/oxidase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AKR1B1 Tclin Aldose reductase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NOX4 Tchem NADPH oxidase 4 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PLG Tclin Plasminogen (2339 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PRSS1 Tclin Trypsin I (2306 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TOP1 Tclin DNA topoisomerase I (7553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TOP2A Tclin DNA topoisomerase II alpha (6317 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TYR Tclin Tyrosinase (717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
XDH Tclin Xanthine dehydrogenase (1038 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ELANE Tclin Leukocyte elastase (8173 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AKR1B1 Tclin Aldose reductase (1404 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LCK Tclin Tyrosine-protein kinase LCK (9212 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1B1 Tchem Cytochrome P450 1B1 (1148 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PON1 Tbio Serum paraoxonase/arylesterase 1 (96 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GSK3B Tclin Glycogen synthase kinase-3 beta (11785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLB Tchem DNA polymerase beta (23632 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CDK6 Tclin Cyclin-dependent kinase 6 (1724 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BCHE Tclin Butyrylcholinesterase (7174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APP Tclin Amyloid-beta A4 protein (8510 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NEU2 Tbio Sialidase 2 (382 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLA Tclin Alpha-galactosidase A (5444 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AMY1A Salivary alpha-amylase (100 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PIM1 Tchem Serine/threonine-protein kinase PIM1 (9629 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SYK Tclin Tyrosine-protein kinase SYK (7372 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP3 Tchem Matrix metalloproteinase 3 (3433 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A1 Tchem Cytochrome P450 1A1 (1169 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX12 Tchem Arachidonate 12-lipoxygenase (3262 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DAPK1 Tchem Death-associated protein kinase 1 (1664 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR1H3 Tchem LXR-alpha (2891 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FBP1 Tchem Fructose-1,6-bisphosphatase (1199 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FASN Tchem Fatty acid synthase (3390 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

NA Neuraminidase (1107 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
fabI Enoyl-[acyl-carrier-protein] reductase (206 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ca7 Carbonic anhydrase VII (3 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Glo1 Glyoxalase I (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ttr Transthyretin (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp13 Matrix metalloproteinase 13 (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cruzipain (33337 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Gusb Beta-glucuronidase (17 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DPP4 Dipeptidyl peptidase IV (11 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcb1b P-glycoprotein 1 (174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA4 Carbonic anhydrase IV (1713 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp2 Matrix metalloproteinase-2 (12 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ptpn1 Protein-tyrosine phosphatase 1B (270 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pol Human immunodeficiency virus type 1 integrase (9041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
M1AAP Zinc aminopeptidase (902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAL62 Alpha-glucosidase MAL62 (106 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichophyton benhamiae (1686 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus pneumoniae (31063 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas fluorescens (1630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterobacter cloacae (7976 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Proteus vulgaris (5823 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Salmonella typhimurium (15756 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Micrococcus luteus (7463 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus epidermidis (22802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Neisseria gonorrhoeae (1461 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus subtilis (32866 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium tuberculosis (203094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterococcus faecalis (29875 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pichia kudriavzevii (7448 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aspergillus fumigatus (16427 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei brucei (13300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Entamoeba histolytica (2676 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nakaseomyces glabratus (9108 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida parapsilosis (8521 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida tropicalis (8381 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichophyton rubrum (3646 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania donovani (89745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma cruzi (99888 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human alphaherpesvirus 1 (11089 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488195204
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488195204
IUPAC Name 2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
INCHI InChI=1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H
InChi Key IQPNAANSBPBGFQ-UHFFFAOYSA-N
Canonical SMILES C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O
Isomeric SMILES C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O
WGK Germany 3
RTECS LK9275210
PubChem CID 5280445
Molecular Weight 286.24
Beilstein 292084
Reaxy-Rn 292084

Certificates

Certificate of Analysis(COA)

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38 results found

Lot NumberCertificate TypeDateItem
D2430096Certificate of AnalysisMay 11, 2024 L107329
D2430095Certificate of AnalysisMay 11, 2024 L107329
D2430091Certificate of AnalysisMay 11, 2024 L107329
D2430090Certificate of AnalysisMay 11, 2024 L107329
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C2406170Certificate of AnalysisMar 09, 2024 L107329
C2406169Certificate of AnalysisMar 09, 2024 L107329
C2406171Certificate of AnalysisMar 09, 2024 L107329
C2406232Certificate of AnalysisMar 09, 2024 L107329
C2406233Certificate of AnalysisMar 09, 2024 L107329
C2406234Certificate of AnalysisMar 09, 2024 L107329
G2313868Certificate of AnalysisJul 25, 2023 L107329
G2313848Certificate of AnalysisJul 25, 2023 L107329
L2315075Certificate of AnalysisJul 19, 2023 L107329
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G2313867Certificate of AnalysisJul 19, 2023 L107329
G2313866Certificate of AnalysisJul 19, 2023 L107329
G2313859Certificate of AnalysisJul 19, 2023 L107329
D2325759Certificate of AnalysisMay 10, 2023 L107329
D2325758Certificate of AnalysisMay 10, 2023 L107329
D2325757Certificate of AnalysisMay 10, 2023 L107329
D2325704Certificate of AnalysisMay 10, 2023 L107329
D2325756Certificate of AnalysisMay 09, 2023 L107329
D2325762Certificate of AnalysisMay 09, 2023 L107329
D2325752Certificate of AnalysisMay 09, 2023 L107329
D2325751Certificate of AnalysisMay 09, 2023 L107329
D2325755Certificate of AnalysisMay 08, 2023 L107329
D2325700Certificate of AnalysisMay 08, 2023 L107329
D2325745Certificate of AnalysisMay 08, 2023 L107329
D2325744Certificate of AnalysisMay 08, 2023 L107329
L1806184Certificate of AnalysisSep 22, 2022 L107329
L1807023Certificate of AnalysisSep 21, 2022 L107329
F2215582Certificate of AnalysisJun 18, 2022 L107329
F2215581Certificate of AnalysisJun 18, 2022 L107329
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D2101255Certificate of AnalysisApr 25, 2021 L107329

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Chemical and Physical Properties

SolubilitySolvent:1eq. NaOH, Max Conc. mg/mL: 1.43, Max Conc. mM: 5; Solvent:DMSO, Max Conc. mg/mL: 14.31, Max Conc. mM: 50
SensitivityHeat Sensitive
Melt Point(°C)330°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS LK9275210
Reaxy-Rn 292084
Merck Index 5614

Related Documents

Citations of This Product

1. Ziyuan Deng, Chengling Lai, Jun Zhang, Fan Sun, Danting Li, Peiying Hao, Xuping Shentu, Kun Pang, Xiaoping Yu.  (2024)  Effects of Secondary Metabolites of Rice on Brown Planthopper and Its Symbionts.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  25  (1): (386).  [PMID:38203556]
2. Jingjing Zhen, Faguang Ma, Jing Yan, Rongxin Lin, Ming Yan, Yilin Wu.  (2024)  Synthesis of metal-organic framework hybrid nanocomposites based on MOFs@C3N4 with high selective separation ability for luteolin.  SEPARATION AND PURIFICATION TECHNOLOGY,  335  (126139).  [PMID:]
3. Defeng Wen, Wantong Han, Quan Chen, Guanhui Qi, Mengling Gao, Pu Guo, Yu Liu, Zhongyuan Wu, Shulin Fu, Qirong Lu, Yinsheng Qiu.  (2024)  Integrating network pharmacology and experimental validation to explore the mechanisms of luteolin in alleviating fumonisin B1–induced intestinal inflammatory injury.  TOXICON,  237  (1): (107531).  [PMID:38013056]
4. Shucheng Liu, Zhi Hu, Xuan Zhang, Hao Huang, Jianming Pan, Hongxiang Ou.  (2024)  Fabrication of double imprinted anchor points in cellulose nanocrystals-based hierarchical porous polyHIPEs for selective separation of flavoniods under physiological pH.  JOURNAL OF HAZARDOUS MATERIALS,  465  (133230).  [PMID:38134695]
5. Guo Zhonghui, Li Jieming, Luo Di, Zhang Mingxia.  (2023)  Novel ecological implications of non-toxic Microcystis towards toxic ecotype in population—promoting toxic ecotype dominance at various N levels and cooperative defense against luteolin-stress.  FEMS MICROBIOLOGY ECOLOGY,  99  (12):   [PMID:37884453]
6. Yueqin Li, Yunzhen Zhang, Lezhen Dong, Ying Li, Yahui Liu, Yang Liu, Lingyi Liu, Lianliang Liu.  (2024)  Fermentation of Lactobacillus fermentum NB02 with feruloyl esterase production increases the phenolic compounds content and antioxidant properties of oat bran.  FOOD CHEMISTRY,  437  (15): (137834).  [PMID:37897817]
7. Faguang Ma, Ming Yan, Rongxin Lin, Yilin Wu, Jianming Pan.  (2024)  Boronate-affinity sol–gel-imprinted membranes with MOFs-functionalized rotary-evaporating layers for high-precision specific recognition.  SEPARATION AND PURIFICATION TECHNOLOGY,  330  (125458).  [PMID:8107964]
8. Liwei Xue, Xiaosheng Jin, Tingting Ji, Rongzhou Li, Xiaoju Zhuge, Fang Xu, Zijiao Quan, Haibin Tong, Weilai Yu.  (2023)  Luteolin ameliorates DSS-induced colitis in mice via suppressing macrophage activation and chemotaxis.  INTERNATIONAL IMMUNOPHARMACOLOGY,  124  (3): (110996).  [PMID:37776768]
9. Yang You, Yipu Liu, Chuchu Ma, Jianpei Xu, Laozhi Xie, Shiqiang Tong, Yinzhe Sun, Fenfen Ma, Yukun Huang, Junbin Liu, Wenze Xiao, Chengxiang Dai, Suke Li, Jigang Lei, Qiyong Mei, Xiaoling Gao, Jun Chen.  (2023)  Surface-tethered ROS-responsive micelle backpacks for boosting mesenchymal stem cell vitality and modulating inflammation in ischemic stroke treatment.  JOURNAL OF CONTROLLED RELEASE,  362  (210).  [PMID:37619863]
10. Dan Wang, He Li, Tian-Yu Hou, Zhi-Jun Zhang, Hui-Zhen Li.  (2023)  Effects of conjugated interactions between Perilla seed meal proteins and different polyphenols on the structural and functional properties of proteins.  FOOD CHEMISTRY,    (137345).  [PMID:37666124]
11. Mingcai Ma, Xiaofeng Lu, Licheng Wang, Yong Guo, Hui Ding, Shuai Wang, Xiaojing Liang.  (2023)  A stable core-shell metal-organic framework@covalent organic framework composite as solid-phase extraction adsorbent for selective enrichment and determination of flavonoids.  JOURNAL OF CHROMATOGRAPHY A,  1707  (464324).  [PMID:37634259]
12. Song Jie, Zhang Rong, Han Jiaxuan, Dou Yufang, Yu Shuang, Ma Xiaoyan.  (2023)  Preparation and Performance Study of Polybutylene Succinate/Esterified Modified Luteolin Composite Materials.  JOURNAL OF POLYMERS AND THE ENVIRONMENT,    (1-14).  [PMID:]
13. Mubashar Hassan, Yanan Wang, Shahid Ali Rajput, Aftab Shaukat, Ping Yang, Muhammad Zahid Farooq, Qianhui Cheng, Mehboob Ali, Xiaomei Mi, Yu An, Desheng Qi.  (2023)  Ameliorative Effects of Luteolin and Activated Charcoal on Growth Performance, Immunity Function, and Antioxidant Capacity in Broiler Chickens Exposed to Deoxynivalenol.  Toxins,  15  (8): (478).  [PMID:37624235]
14. Dong Li, Chunran Zhou, Shuai Wang, Zhan Hu, Jia Xie, Canping Pan, Ranfeng Sun.  (2023)  Imidacloprid-induced stress affects the growth of pepper plants by disrupting rhizosphere-plant microbial and metabolite composition.  SCIENCE OF THE TOTAL ENVIRONMENT,  898  (165395).  [PMID:37437628]
15. Renjie Li, Jin Chen, Huihui Li, Zhuangwei Zhang, Hongjin Tang.  (2023)  Effects of calcium ions on the particle performance of luteolin-loaded zein-gum arabic-tea polyphenols ternary complex nanoparticles.  LWT-FOOD SCIENCE AND TECHNOLOGY,  184  (115057).  [PMID:]
16. Saif Ullah, Gang Hu, Mati Ur Rahman, Asif Hayat, Ata Ur Rehman, Ijaz Ullah, Akhlaq Ahmad, Waqar Uddin, Wen Ma, Zhaohui Fang, Muhammad Yasir Nawabi, Rooh Ullah, Jimei Song.  (2019)  Evaluation of Antioxidants Activity of Some Natural Polyphenolic Compounds By using Briggs-Rauscher Reaction.  International Journal of Electrochemical Science,  14  (10176).  [PMID:]
17. Qiao-Ting Xu, Wen-Xuan Zhang, Hai-Xia Xu, Qing-Feng Zhang.  (2023)  Fabrication of Luteolin Loaded Zein-Caseinate Nanoparticles and its Bioavailability Enhancement in Rats.  JOURNAL OF PHARMACEUTICAL SCIENCES,      [PMID:37356712]
18. Yimei Zheng, Chengang Zhao, Boyu Chen, Hui Teng, Chao Ai, Lei Chen.  (2023)  D-α-tocopherol polyethylene glycol 1000 succinate-based microemulsion delivery system: Stability enhancement of physicochemical properties of luteolin.  FOOD CHEMISTRY,  426  (136587).  [PMID:37364422]
19. Xu Yang-ding, Guo Yu-jie, Mao He-rong, Xiong Zhi-xiang, Luo Meng-yu, Luo Rui-qi, Lu Shan, Huang Lu, Hong Yi.  (2023)  Integration of transcriptomics and proteomics to elucidate inhibitory effect and mechanism of rosmarinic acid from Perilla frutescens (L.) Britt. in treating Trichophyton mentagrophytes.  Chinese Medicine,  18  (1): (1-20).  [PMID:37280712]
20. Jingtong Xia, Jiahao Zhou, Yanlong Liu, Na Yan, Xiaowen Hu, Lei Zhou, Qiaosheng Pu.  (2023)  Non-destructive distinction of single seed for Medicago sativa and Melilotus officinalis by capillary electrophoresis with laser-induced fluorescence detection.  JOURNAL OF CHROMATOGRAPHY A,  1704  (464116).  [PMID:37290349]
21. Dongwei Wei, Wuyong Sun, Mingren Huang, Xiaoning Zeng, Yun Chen, Zhiliang Yuan.  (2023)  Phenolic Characterization and Antioxidant Activity of Chrysanthemum indicum and Opisthopappus Shih during Different Growth Stages.  CHEMISTRY & BIODIVERSITY,  20  (7): (e202300370).  [PMID:37263981]
22. Renjie Li, Zhuangwei Zhang, Jin Chen, Huihui Li, Hongjin Tang.  (2023)  Investigating of zein-gum arabic-tea polyphenols ternary complex nanoparticles for luteolin encapsulation: Fabrication, characterization, and functional performance.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  242  (125059).  [PMID:37244348]
23. Haiyun Yang, Zhiqing Peng, Liuming Xie, Jianhua Xie, Zhibing Huang.  (2023)  Adding genistein or luteolin decreased the yield of citrinin and without reducing pigments in yam solid-fermentation by Monascus.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,  103  (13): (6440-6451).  [PMID:37209398]
24. Mengsi Zhang, Lu Wang, Hao Jin, Nan Zhao, Yi Liu, Shijie Lan, Shuwei Liu, Hao Zhang.  (2023)  Employing single valency polyphenol to prepare metal-phenolic network antitumor reagents through FeOOH assistance.  JOURNAL OF CONTROLLED RELEASE,  358  (612).  [PMID:37196899]
25. Shaoyan Zhang, Jinfeng Ning, Qingqing Wang, Wei Wang.  (2023)  Fluorescence enhancement of flavonoids and its application in ingredient determination for some traditional Chinese medicines by CE-LIF.  Analytical Methods,  15  (24): (2964-2970).  [PMID:37309583]
26. Lei He, Qian Hu, Liyang Wei, Xuliyang Ge, Ning Yu, Ying Chen.  (2023)  Unravelling dynamic changes in non-volatile and volatile metabolites of pulses during soaking: An integrated metabolomics approach.  FOOD CHEMISTRY,  422  (136231).  [PMID:37141754]
27. Shengbiao Zheng, Tianna Liu, Nini Zhang, Liang Li, Yanli Zhu, Erhui Zhang, Jing Tang, Jiahao Guo.  (2023)  A 3D flower-like Co/Ni bimetallic organic framework as an excellent material for electrochemical determination of quercetin.  NEW JOURNAL OF CHEMISTRY,  47  (16): (7566-7574).  [PMID:]
28. Xueli Xu, Yangyang Shi, Qingwen Yu, Yajie Peng, Fei Zhao, Jing Cui, Yajing Chen, Lingxu Liu, Yiran Zhang, Ji Zhang, Bo Wei.  (2023)  Coumarin-derived imino sulfonate 5h ameliorates cardiac injury induced by myocardial infarction via activating the Sirt1/Nrf2 signaling pathway.  EUROPEAN JOURNAL OF PHARMACOLOGY,  945  (175615).  [PMID:36841283]
29. Dongdong Xu, Wanbo Zhu, Cheng Ding, Jiawei Mei, Jun Zhou, Tao Cheng, Geyong Guo, Xianlong Zhang.  (2023)  Self-Homeostasis Immunoregulatory Strategy for Implant-Related Infections through Remodeling Redox Balance.  ACS Nano,  17  (5): (4574–4590).  [PMID:36811805]
30. Shengxiang Yi, Gaowei Zhang, Mingyan Liu, Wenjie Yu, Guohua Cheng, Liping Luo, Fangjian Ning.  (2023)  Citrus Honey Ameliorates Liver Disease and Restores Gut Microbiota in Alcohol–Feeding Mice.  Nutrients,  15  (5): (1078).  [PMID:36904078]
31. Jia Gao, Li Chen, Wendong Xing, Chao Yu, Yongsheng Yan, Yilin Wu.  (2023)  “Nanomagnet-inspired” design on molecularly imprinted nanofiber membrane: Mechanisms for improved transport selectivity of sufficient specific sites.  JOURNAL OF MEMBRANE SCIENCE,  672  (121467).  [PMID:]
32. Chun Xiao Li, Fu Rong Wang, Bing Zhang, Ze Yuan Deng, Hong Yan Li.  (2023)  Stability and antioxidant activity of phenolic compounds during in vitro digestion.  JOURNAL OF FOOD SCIENCE,  88  (2): (696-716).  [PMID:36617678]
33. Mang-Mang Li, Yi-Ting Chen, Jin-Cang Ruan, Wen-Jun Wang, Ji-Guang Chen, Qing-Feng Zhang.  (2023)  Structure-activity relationship of dietary flavonoids on pancreatic lipase.  Current Research in Food Science,  (100424).  [PMID:36618100]
34. Fengxia Tang, Chuan Li, Xiaoran Yang, Jiandu Lei, Hongxia Chen, Changwei Zhang, Chengzhang Wang.  (2023)  Effect of Variety and Maturity Index on the Physicochemical Parameters Related to Virgin Olive Oil from Wudu (China).  Foods,  12  (1): (7).  [PMID:36613224]
35. Xiaoqi Hong, Yujin Jian, Shenghao Ding, Jianpo Zhou, Xiaoli Zheng, Huimin Zhang, Butian Zhou, Canbin Zhuang, Jieqing Wan, Xiaoping Tong.  (2023)  Kir4.1 channel activation in NG2 glia contributes to remyelination in ischemic stroke.  EBioMedicine,  87  (104406).  [PMID:36527899]
36. Yue Huang, Xiaojing Si, Mei Han, Chen Bai.  (2022)  Rapid and Sensitive Detection of Rutin in Food Based on Nitrogen-Doped Carbon Quantum Dots as Fluorescent Probe.  MOLECULES,  27  (24): (8834).  [PMID:36557970]
37. Zhixu Chen, Jincai Wang, Jiaming Yuan, Zhen Wang, Zhengchao Tu, Jacques Crommen, Wenhui Luo, Jialiang Guo, Tingting Zhang, Zhengjin Jiang.  (2023)  Rapid screening of neuraminidase inhibitors using an at-line nanofractionation platform involving parallel oseltamivir-sensitive/resistant neuraminidase bioassays.  JOURNAL OF CHROMATOGRAPHY A,  1687  (463693).  [PMID:36516530]
38. Wenjie Yu, Fengjie Sun, Ruixin Xu, Meng Cui, Yongquan Liu, Quanyuan Xie, Limin Guo, Chenxian Kong, Xin Li, Xiali Guo, Liping Luo.  (2023)  Chemical composition and anti-inflammatory activities of Castanopsis honey.  Food & Function,  14  (1): (250-261).  [PMID:36484340]
39. Lingli Zhao, Mengfei Zheng, Hao Cai, Juan Chen, Yan Lin, Fangbin Wang, Lu Wang, Xian Zhang, Jian Liu.  (2023)  The activity comparison of six dietary flavonoids identifies that luteolin inhibits 3T3-L1 adipocyte differentiation through reducing ROS generation.  JOURNAL OF NUTRITIONAL BIOCHEMISTRY,  112  (109208).  [PMID:36370929]
40. Liang Jin, Yumei Zhang, Jiehong Yang, Huifen Zhou, Gaozhi Jia, Yu He, Haitong Wan.  (2022)  Investigation of Pharmacological Mechanisms of Yinhua Pinggan Granule on the Treatment of Pneumonia through Network Pharmacology and In Vitro.  Biomed Research International,  2022  (1602447).  [PMID:36389108]
41. Xuan Chen, Liufeng Zheng, Bing Zhang, Zeyuan Deng, Hongyan Li.  (2022)  Synergistic protection of quercetin and lycopene against oxidative stress via SIRT1-Nox4-ROS axis in HUVEC cells.  Current Research in Food Science,  (1985).  [PMID:36304485]
42. Jingyi Jian, Jiaming Yuan, Yu Fan, Jincai Wang, Tingting Zhang, Jeroen Kool, Zhengjin Jiang.  (2022)  High-Resolution Bioassay Profiling with Complemented Sensitivity and Resolution for Pancreatic Lipase Inhibitor Screening.  MOLECULES,  27  (20): (6923).  [PMID:36296516]
43. Rongqian Meng, Yanfeng Xue, Lijun Guo, Hong Yang, Yongbo Song, Qiaoling Li, Yulan Niu.  (2022)  Overoxidized polypyrrole/overoxidized poly(3,4-ethylenedioxythiophene)/graphene quantum dots-chitosan as enhanced electrochemical sensing platform for luteolin determination in peanut shells.  NEW JOURNAL OF CHEMISTRY,  46  (43): (20610-20622).  [PMID:]
44. Guo Wei, Luo Lianxiang, Meng Yan, Chen Wen, Yu Lixiu, Zhang Cong, Qiu Zhenpeng, Cao Peng.  (2022)  Luteolin alleviates methionine–choline-deficient diet-induced non-alcoholic steatohepatitis by modulating host serum metabolome and gut microbiome.  Frontiers in Nutrition,    [PMID:35990349]
45. Jia Gao, Qingyan Guo, Yan Yan, Chao Yu, Muning Chen, Wendong Xing, Li Yan, Yongsheng Yan, Yilin Wu.  (2022)  Templating precise multiple binding sites: Promising molecularly imprinted membrane orchestrated by sequential surface imprinting strategy.  CHEMICAL ENGINEERING JOURNAL,  450  (138058).  [PMID:]
46. Mehmood Sahid, Uddin Md Alim, Yu Haojie, Wang Li, Amin Bilal Ul, Haq Fazal, Fahad Shah, Haroon Muhammad.  (2022)  Study on synthesis of cross-linked poly(cyclotriphosphazene-co-luteolin) nanospheres and their properties for controlled drug delivery.  COLLOID AND POLYMER SCIENCE,  300  (7): (861-871).  [PMID:]
47. Yu Wang, Zhi-jian Lin, Jing Huang, Meng-zhen Chu, Xue-li Ding, Wen-jing Li, Qiu-yue Mao, Bing Zhang.  (2022)  An integrated study of Shenling Baizhu San against hyperuricemia: Efficacy evaluation, core target identification and active component discovery.  JOURNAL OF ETHNOPHARMACOLOGY,  295  (115450).  [PMID:35688256]
48. Liu Xia, Zhang Mengying, Tian Yuxin, Liu Ruijia, Wang Yunfei, Guo Feifei, Gong Yanling, Yan Meixing.  (2022)  Development, Characterization, and Investigation of In Vivo Targeted Delivery Efficacy of Luteolin-Loaded, Eudragit S100-Coated mPEG-PLGA Nanoparticles.  AAPS PHARMSCITECH,  23  (4): (1-10).  [PMID:35348949]
49. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang.  (2022)  Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin.  Food & Function,  13  (9): (5061-5074).  [PMID:35404372]
50. Chen Tan, Heng Fan, Jiahui Ding, Chaoqun Han, Yang Guan, Feng Zhu, Hui Wu, Yujin Liu, Wei Zhang, Xiaohua Hou, Songwei Tan, Qing Tang.  (2022)  ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment.  Materials Today Bio,  14  (100246).  [PMID:35372817]
51. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang.  (2022)  Multispectroscopic and computational evaluation of the binding of flavonoids with bovine serum albumin in the presence of Cu2+.  FOOD CHEMISTRY,  385  (132656).  [PMID:35279499]
52. Cong-Jie PAN, Tian-Tian CHEN, Long-Fei MA, Xue-Zhen QIN, Qiao-Qiao WEN, Su-Xiang FENG.  (2022)  One-pot facile synthesis of bright blue emitting silicon nanoparticles for sensitive detection of luteolin via inner filter effect.  CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,  50  (100069).  [PMID:]
53. Jie Pan, Xiaoping Cai, Xiao Zheng, Xiaoyu Zhu, Jihong Feng, Xiaoqiu Wang.  (2022)  Luteolin inhibits viability, migration, angiogenesis and invasion of non-small cell lung cancer vascular endothelial cells via miR-133a-3p/purine rich element binding protein B-mediated MAPK and PI3K/Akt signaling pathways.  TISSUE & CELL,  75  (101740).  [PMID:35101688]
54. Huang Hui, Xie Shuqian, Deng Lu, Yuan Jie, Yue Ruirui, Xu Jingkun.  (2022)  Fabrication of rGO/MXene-Pd/rGO hierarchical framework as high-performance electrochemical sensing platform for luteolin detection.  MICROCHIMICA ACTA,  189  (2): (1-10).  [PMID:35015150]
55. Yonglin Li, Shasha Wen, Yiwen Sun, Na Zhang, Yuan Gao, Xiuzhu Yu.  (2022)  New Method Based on Polarity Reversal for Detecting Adulteration of Extra Virgin Olive Oil with Refined Olive Pomace Oil.  EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY,  124  (4): (2100193).  [PMID:]
56. Yang Wenning, Jiang Xiaoquan, Liu Jingtong, Qi Dongying, Luo Zhiqiang, Yu Guohua, Li Xueyan, Sen Muli, Chen Hongjiao, Liu Wei, Liu Yang, Wang Guopeng.  (2021)  Integrated Strategy From In Vitro, In Situ, In Vivo to In Silico for Predicting Active Constituents and Exploring Molecular Mechanisms of Tongfengding Capsule for Treating Gout by Inhibiting Inflammatory Responses.  Frontiers in Pharmacology,  12  (3287).  [PMID:34912220]
57. Yonggang Du, Ge Zhao, Gonghui Shi, Yiming Wang, Wei Li, Shitong Ren.  (2022)  Effect of crosslink structure on mechanical properties, thermal stability and flame retardancy of natural flavonoid based epoxy resins.  EUROPEAN POLYMER JOURNAL,  162  (110898).  [PMID:]
58. Lu Zhao, Hao Liu, Yingchao Wang, Shufang Wang, Dejin Xun, Yi Wang, Yiyu Cheng, Boli Zhang.  (2023)  Multimodal Identification by Transcriptomics and Multiscale Bioassays of Active Components in Xuanfeibaidu Formula to Suppress Macrophage-Mediated Immune Response.  Engineering,  20  (63).  [PMID:34815890]
59. Stoyan Dirimanov,Petra Högger.  (2019-06-15)  Screening of Inhibitory Effects of Polyphenols on Akt-Phosphorylation in Endothelial Cells and Determination of Structure-Activity Features..  Biomolecules,  ((6)):   [PMID:31195734]

References

1. Ziyuan Deng, Chengling Lai, Jun Zhang, Fan Sun, Danting Li, Peiying Hao, Xuping Shentu, Kun Pang, Xiaoping Yu.  (2024)  Effects of Secondary Metabolites of Rice on Brown Planthopper and Its Symbionts.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  25  (1): (386).  [PMID:38203556]
2. Jingjing Zhen, Faguang Ma, Jing Yan, Rongxin Lin, Ming Yan, Yilin Wu.  (2024)  Synthesis of metal-organic framework hybrid nanocomposites based on MOFs@C3N4 with high selective separation ability for luteolin.  SEPARATION AND PURIFICATION TECHNOLOGY,  335  (126139).  [PMID:]
3. Defeng Wen, Wantong Han, Quan Chen, Guanhui Qi, Mengling Gao, Pu Guo, Yu Liu, Zhongyuan Wu, Shulin Fu, Qirong Lu, Yinsheng Qiu.  (2024)  Integrating network pharmacology and experimental validation to explore the mechanisms of luteolin in alleviating fumonisin B1–induced intestinal inflammatory injury.  TOXICON,  237  (1): (107531).  [PMID:38013056]
4. Shucheng Liu, Zhi Hu, Xuan Zhang, Hao Huang, Jianming Pan, Hongxiang Ou.  (2024)  Fabrication of double imprinted anchor points in cellulose nanocrystals-based hierarchical porous polyHIPEs for selective separation of flavoniods under physiological pH.  JOURNAL OF HAZARDOUS MATERIALS,  465  (133230).  [PMID:38134695]
5. Guo Zhonghui, Li Jieming, Luo Di, Zhang Mingxia.  (2023)  Novel ecological implications of non-toxic Microcystis towards toxic ecotype in population—promoting toxic ecotype dominance at various N levels and cooperative defense against luteolin-stress.  FEMS MICROBIOLOGY ECOLOGY,  99  (12):   [PMID:37884453]
6. Yueqin Li, Yunzhen Zhang, Lezhen Dong, Ying Li, Yahui Liu, Yang Liu, Lingyi Liu, Lianliang Liu.  (2024)  Fermentation of Lactobacillus fermentum NB02 with feruloyl esterase production increases the phenolic compounds content and antioxidant properties of oat bran.  FOOD CHEMISTRY,  437  (15): (137834).  [PMID:37897817]
7. Faguang Ma, Ming Yan, Rongxin Lin, Yilin Wu, Jianming Pan.  (2024)  Boronate-affinity sol–gel-imprinted membranes with MOFs-functionalized rotary-evaporating layers for high-precision specific recognition.  SEPARATION AND PURIFICATION TECHNOLOGY,  330  (125458).  [PMID:8107964]
8. Liwei Xue, Xiaosheng Jin, Tingting Ji, Rongzhou Li, Xiaoju Zhuge, Fang Xu, Zijiao Quan, Haibin Tong, Weilai Yu.  (2023)  Luteolin ameliorates DSS-induced colitis in mice via suppressing macrophage activation and chemotaxis.  INTERNATIONAL IMMUNOPHARMACOLOGY,  124  (3): (110996).  [PMID:37776768]
9. Yang You, Yipu Liu, Chuchu Ma, Jianpei Xu, Laozhi Xie, Shiqiang Tong, Yinzhe Sun, Fenfen Ma, Yukun Huang, Junbin Liu, Wenze Xiao, Chengxiang Dai, Suke Li, Jigang Lei, Qiyong Mei, Xiaoling Gao, Jun Chen.  (2023)  Surface-tethered ROS-responsive micelle backpacks for boosting mesenchymal stem cell vitality and modulating inflammation in ischemic stroke treatment.  JOURNAL OF CONTROLLED RELEASE,  362  (210).  [PMID:37619863]
10. Dan Wang, He Li, Tian-Yu Hou, Zhi-Jun Zhang, Hui-Zhen Li.  (2023)  Effects of conjugated interactions between Perilla seed meal proteins and different polyphenols on the structural and functional properties of proteins.  FOOD CHEMISTRY,    (137345).  [PMID:37666124]
11. Mingcai Ma, Xiaofeng Lu, Licheng Wang, Yong Guo, Hui Ding, Shuai Wang, Xiaojing Liang.  (2023)  A stable core-shell metal-organic framework@covalent organic framework composite as solid-phase extraction adsorbent for selective enrichment and determination of flavonoids.  JOURNAL OF CHROMATOGRAPHY A,  1707  (464324).  [PMID:37634259]
12. Song Jie, Zhang Rong, Han Jiaxuan, Dou Yufang, Yu Shuang, Ma Xiaoyan.  (2023)  Preparation and Performance Study of Polybutylene Succinate/Esterified Modified Luteolin Composite Materials.  JOURNAL OF POLYMERS AND THE ENVIRONMENT,    (1-14).  [PMID:]
13. Mubashar Hassan, Yanan Wang, Shahid Ali Rajput, Aftab Shaukat, Ping Yang, Muhammad Zahid Farooq, Qianhui Cheng, Mehboob Ali, Xiaomei Mi, Yu An, Desheng Qi.  (2023)  Ameliorative Effects of Luteolin and Activated Charcoal on Growth Performance, Immunity Function, and Antioxidant Capacity in Broiler Chickens Exposed to Deoxynivalenol.  Toxins,  15  (8): (478).  [PMID:37624235]
14. Dong Li, Chunran Zhou, Shuai Wang, Zhan Hu, Jia Xie, Canping Pan, Ranfeng Sun.  (2023)  Imidacloprid-induced stress affects the growth of pepper plants by disrupting rhizosphere-plant microbial and metabolite composition.  SCIENCE OF THE TOTAL ENVIRONMENT,  898  (165395).  [PMID:37437628]
15. Renjie Li, Jin Chen, Huihui Li, Zhuangwei Zhang, Hongjin Tang.  (2023)  Effects of calcium ions on the particle performance of luteolin-loaded zein-gum arabic-tea polyphenols ternary complex nanoparticles.  LWT-FOOD SCIENCE AND TECHNOLOGY,  184  (115057).  [PMID:]
16. Saif Ullah, Gang Hu, Mati Ur Rahman, Asif Hayat, Ata Ur Rehman, Ijaz Ullah, Akhlaq Ahmad, Waqar Uddin, Wen Ma, Zhaohui Fang, Muhammad Yasir Nawabi, Rooh Ullah, Jimei Song.  (2019)  Evaluation of Antioxidants Activity of Some Natural Polyphenolic Compounds By using Briggs-Rauscher Reaction.  International Journal of Electrochemical Science,  14  (10176).  [PMID:]
17. Qiao-Ting Xu, Wen-Xuan Zhang, Hai-Xia Xu, Qing-Feng Zhang.  (2023)  Fabrication of Luteolin Loaded Zein-Caseinate Nanoparticles and its Bioavailability Enhancement in Rats.  JOURNAL OF PHARMACEUTICAL SCIENCES,      [PMID:37356712]
18. Yimei Zheng, Chengang Zhao, Boyu Chen, Hui Teng, Chao Ai, Lei Chen.  (2023)  D-α-tocopherol polyethylene glycol 1000 succinate-based microemulsion delivery system: Stability enhancement of physicochemical properties of luteolin.  FOOD CHEMISTRY,  426  (136587).  [PMID:37364422]
19. Xu Yang-ding, Guo Yu-jie, Mao He-rong, Xiong Zhi-xiang, Luo Meng-yu, Luo Rui-qi, Lu Shan, Huang Lu, Hong Yi.  (2023)  Integration of transcriptomics and proteomics to elucidate inhibitory effect and mechanism of rosmarinic acid from Perilla frutescens (L.) Britt. in treating Trichophyton mentagrophytes.  Chinese Medicine,  18  (1): (1-20).  [PMID:37280712]
20. Jingtong Xia, Jiahao Zhou, Yanlong Liu, Na Yan, Xiaowen Hu, Lei Zhou, Qiaosheng Pu.  (2023)  Non-destructive distinction of single seed for Medicago sativa and Melilotus officinalis by capillary electrophoresis with laser-induced fluorescence detection.  JOURNAL OF CHROMATOGRAPHY A,  1704  (464116).  [PMID:37290349]
21. Dongwei Wei, Wuyong Sun, Mingren Huang, Xiaoning Zeng, Yun Chen, Zhiliang Yuan.  (2023)  Phenolic Characterization and Antioxidant Activity of Chrysanthemum indicum and Opisthopappus Shih during Different Growth Stages.  CHEMISTRY & BIODIVERSITY,  20  (7): (e202300370).  [PMID:37263981]
22. Renjie Li, Zhuangwei Zhang, Jin Chen, Huihui Li, Hongjin Tang.  (2023)  Investigating of zein-gum arabic-tea polyphenols ternary complex nanoparticles for luteolin encapsulation: Fabrication, characterization, and functional performance.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  242  (125059).  [PMID:37244348]
23. Haiyun Yang, Zhiqing Peng, Liuming Xie, Jianhua Xie, Zhibing Huang.  (2023)  Adding genistein or luteolin decreased the yield of citrinin and without reducing pigments in yam solid-fermentation by Monascus.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,  103  (13): (6440-6451).  [PMID:37209398]
24. Mengsi Zhang, Lu Wang, Hao Jin, Nan Zhao, Yi Liu, Shijie Lan, Shuwei Liu, Hao Zhang.  (2023)  Employing single valency polyphenol to prepare metal-phenolic network antitumor reagents through FeOOH assistance.  JOURNAL OF CONTROLLED RELEASE,  358  (612).  [PMID:37196899]
25. Shaoyan Zhang, Jinfeng Ning, Qingqing Wang, Wei Wang.  (2023)  Fluorescence enhancement of flavonoids and its application in ingredient determination for some traditional Chinese medicines by CE-LIF.  Analytical Methods,  15  (24): (2964-2970).  [PMID:37309583]
26. Lei He, Qian Hu, Liyang Wei, Xuliyang Ge, Ning Yu, Ying Chen.  (2023)  Unravelling dynamic changes in non-volatile and volatile metabolites of pulses during soaking: An integrated metabolomics approach.  FOOD CHEMISTRY,  422  (136231).  [PMID:37141754]
27. Shengbiao Zheng, Tianna Liu, Nini Zhang, Liang Li, Yanli Zhu, Erhui Zhang, Jing Tang, Jiahao Guo.  (2023)  A 3D flower-like Co/Ni bimetallic organic framework as an excellent material for electrochemical determination of quercetin.  NEW JOURNAL OF CHEMISTRY,  47  (16): (7566-7574).  [PMID:]
28. Xueli Xu, Yangyang Shi, Qingwen Yu, Yajie Peng, Fei Zhao, Jing Cui, Yajing Chen, Lingxu Liu, Yiran Zhang, Ji Zhang, Bo Wei.  (2023)  Coumarin-derived imino sulfonate 5h ameliorates cardiac injury induced by myocardial infarction via activating the Sirt1/Nrf2 signaling pathway.  EUROPEAN JOURNAL OF PHARMACOLOGY,  945  (175615).  [PMID:36841283]
29. Dongdong Xu, Wanbo Zhu, Cheng Ding, Jiawei Mei, Jun Zhou, Tao Cheng, Geyong Guo, Xianlong Zhang.  (2023)  Self-Homeostasis Immunoregulatory Strategy for Implant-Related Infections through Remodeling Redox Balance.  ACS Nano,  17  (5): (4574–4590).  [PMID:36811805]
30. Shengxiang Yi, Gaowei Zhang, Mingyan Liu, Wenjie Yu, Guohua Cheng, Liping Luo, Fangjian Ning.  (2023)  Citrus Honey Ameliorates Liver Disease and Restores Gut Microbiota in Alcohol–Feeding Mice.  Nutrients,  15  (5): (1078).  [PMID:36904078]
31. Jia Gao, Li Chen, Wendong Xing, Chao Yu, Yongsheng Yan, Yilin Wu.  (2023)  “Nanomagnet-inspired” design on molecularly imprinted nanofiber membrane: Mechanisms for improved transport selectivity of sufficient specific sites.  JOURNAL OF MEMBRANE SCIENCE,  672  (121467).  [PMID:]
32. Chun Xiao Li, Fu Rong Wang, Bing Zhang, Ze Yuan Deng, Hong Yan Li.  (2023)  Stability and antioxidant activity of phenolic compounds during in vitro digestion.  JOURNAL OF FOOD SCIENCE,  88  (2): (696-716).  [PMID:36617678]
33. Mang-Mang Li, Yi-Ting Chen, Jin-Cang Ruan, Wen-Jun Wang, Ji-Guang Chen, Qing-Feng Zhang.  (2023)  Structure-activity relationship of dietary flavonoids on pancreatic lipase.  Current Research in Food Science,  (100424).  [PMID:36618100]
34. Fengxia Tang, Chuan Li, Xiaoran Yang, Jiandu Lei, Hongxia Chen, Changwei Zhang, Chengzhang Wang.  (2023)  Effect of Variety and Maturity Index on the Physicochemical Parameters Related to Virgin Olive Oil from Wudu (China).  Foods,  12  (1): (7).  [PMID:36613224]
35. Xiaoqi Hong, Yujin Jian, Shenghao Ding, Jianpo Zhou, Xiaoli Zheng, Huimin Zhang, Butian Zhou, Canbin Zhuang, Jieqing Wan, Xiaoping Tong.  (2023)  Kir4.1 channel activation in NG2 glia contributes to remyelination in ischemic stroke.  EBioMedicine,  87  (104406).  [PMID:36527899]
36. Yue Huang, Xiaojing Si, Mei Han, Chen Bai.  (2022)  Rapid and Sensitive Detection of Rutin in Food Based on Nitrogen-Doped Carbon Quantum Dots as Fluorescent Probe.  MOLECULES,  27  (24): (8834).  [PMID:36557970]
37. Zhixu Chen, Jincai Wang, Jiaming Yuan, Zhen Wang, Zhengchao Tu, Jacques Crommen, Wenhui Luo, Jialiang Guo, Tingting Zhang, Zhengjin Jiang.  (2023)  Rapid screening of neuraminidase inhibitors using an at-line nanofractionation platform involving parallel oseltamivir-sensitive/resistant neuraminidase bioassays.  JOURNAL OF CHROMATOGRAPHY A,  1687  (463693).  [PMID:36516530]
38. Wenjie Yu, Fengjie Sun, Ruixin Xu, Meng Cui, Yongquan Liu, Quanyuan Xie, Limin Guo, Chenxian Kong, Xin Li, Xiali Guo, Liping Luo.  (2023)  Chemical composition and anti-inflammatory activities of Castanopsis honey.  Food & Function,  14  (1): (250-261).  [PMID:36484340]
39. Lingli Zhao, Mengfei Zheng, Hao Cai, Juan Chen, Yan Lin, Fangbin Wang, Lu Wang, Xian Zhang, Jian Liu.  (2023)  The activity comparison of six dietary flavonoids identifies that luteolin inhibits 3T3-L1 adipocyte differentiation through reducing ROS generation.  JOURNAL OF NUTRITIONAL BIOCHEMISTRY,  112  (109208).  [PMID:36370929]
40. Liang Jin, Yumei Zhang, Jiehong Yang, Huifen Zhou, Gaozhi Jia, Yu He, Haitong Wan.  (2022)  Investigation of Pharmacological Mechanisms of Yinhua Pinggan Granule on the Treatment of Pneumonia through Network Pharmacology and In Vitro.  Biomed Research International,  2022  (1602447).  [PMID:36389108]
41. Xuan Chen, Liufeng Zheng, Bing Zhang, Zeyuan Deng, Hongyan Li.  (2022)  Synergistic protection of quercetin and lycopene against oxidative stress via SIRT1-Nox4-ROS axis in HUVEC cells.  Current Research in Food Science,  (1985).  [PMID:36304485]
42. Jingyi Jian, Jiaming Yuan, Yu Fan, Jincai Wang, Tingting Zhang, Jeroen Kool, Zhengjin Jiang.  (2022)  High-Resolution Bioassay Profiling with Complemented Sensitivity and Resolution for Pancreatic Lipase Inhibitor Screening.  MOLECULES,  27  (20): (6923).  [PMID:36296516]
43. Rongqian Meng, Yanfeng Xue, Lijun Guo, Hong Yang, Yongbo Song, Qiaoling Li, Yulan Niu.  (2022)  Overoxidized polypyrrole/overoxidized poly(3,4-ethylenedioxythiophene)/graphene quantum dots-chitosan as enhanced electrochemical sensing platform for luteolin determination in peanut shells.  NEW JOURNAL OF CHEMISTRY,  46  (43): (20610-20622).  [PMID:]
44. Guo Wei, Luo Lianxiang, Meng Yan, Chen Wen, Yu Lixiu, Zhang Cong, Qiu Zhenpeng, Cao Peng.  (2022)  Luteolin alleviates methionine–choline-deficient diet-induced non-alcoholic steatohepatitis by modulating host serum metabolome and gut microbiome.  Frontiers in Nutrition,    [PMID:35990349]
45. Jia Gao, Qingyan Guo, Yan Yan, Chao Yu, Muning Chen, Wendong Xing, Li Yan, Yongsheng Yan, Yilin Wu.  (2022)  Templating precise multiple binding sites: Promising molecularly imprinted membrane orchestrated by sequential surface imprinting strategy.  CHEMICAL ENGINEERING JOURNAL,  450  (138058).  [PMID:]
46. Mehmood Sahid, Uddin Md Alim, Yu Haojie, Wang Li, Amin Bilal Ul, Haq Fazal, Fahad Shah, Haroon Muhammad.  (2022)  Study on synthesis of cross-linked poly(cyclotriphosphazene-co-luteolin) nanospheres and their properties for controlled drug delivery.  COLLOID AND POLYMER SCIENCE,  300  (7): (861-871).  [PMID:]
47. Yu Wang, Zhi-jian Lin, Jing Huang, Meng-zhen Chu, Xue-li Ding, Wen-jing Li, Qiu-yue Mao, Bing Zhang.  (2022)  An integrated study of Shenling Baizhu San against hyperuricemia: Efficacy evaluation, core target identification and active component discovery.  JOURNAL OF ETHNOPHARMACOLOGY,  295  (115450).  [PMID:35688256]
48. Liu Xia, Zhang Mengying, Tian Yuxin, Liu Ruijia, Wang Yunfei, Guo Feifei, Gong Yanling, Yan Meixing.  (2022)  Development, Characterization, and Investigation of In Vivo Targeted Delivery Efficacy of Luteolin-Loaded, Eudragit S100-Coated mPEG-PLGA Nanoparticles.  AAPS PHARMSCITECH,  23  (4): (1-10).  [PMID:35348949]
49. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang.  (2022)  Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin.  Food & Function,  13  (9): (5061-5074).  [PMID:35404372]
50. Chen Tan, Heng Fan, Jiahui Ding, Chaoqun Han, Yang Guan, Feng Zhu, Hui Wu, Yujin Liu, Wei Zhang, Xiaohua Hou, Songwei Tan, Qing Tang.  (2022)  ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment.  Materials Today Bio,  14  (100246).  [PMID:35372817]
51. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang.  (2022)  Multispectroscopic and computational evaluation of the binding of flavonoids with bovine serum albumin in the presence of Cu2+.  FOOD CHEMISTRY,  385  (132656).  [PMID:35279499]
52. Cong-Jie PAN, Tian-Tian CHEN, Long-Fei MA, Xue-Zhen QIN, Qiao-Qiao WEN, Su-Xiang FENG.  (2022)  One-pot facile synthesis of bright blue emitting silicon nanoparticles for sensitive detection of luteolin via inner filter effect.  CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,  50  (100069).  [PMID:]
53. Jie Pan, Xiaoping Cai, Xiao Zheng, Xiaoyu Zhu, Jihong Feng, Xiaoqiu Wang.  (2022)  Luteolin inhibits viability, migration, angiogenesis and invasion of non-small cell lung cancer vascular endothelial cells via miR-133a-3p/purine rich element binding protein B-mediated MAPK and PI3K/Akt signaling pathways.  TISSUE & CELL,  75  (101740).  [PMID:35101688]
54. Huang Hui, Xie Shuqian, Deng Lu, Yuan Jie, Yue Ruirui, Xu Jingkun.  (2022)  Fabrication of rGO/MXene-Pd/rGO hierarchical framework as high-performance electrochemical sensing platform for luteolin detection.  MICROCHIMICA ACTA,  189  (2): (1-10).  [PMID:35015150]
55. Yonglin Li, Shasha Wen, Yiwen Sun, Na Zhang, Yuan Gao, Xiuzhu Yu.  (2022)  New Method Based on Polarity Reversal for Detecting Adulteration of Extra Virgin Olive Oil with Refined Olive Pomace Oil.  EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY,  124  (4): (2100193).  [PMID:]
56. Yang Wenning, Jiang Xiaoquan, Liu Jingtong, Qi Dongying, Luo Zhiqiang, Yu Guohua, Li Xueyan, Sen Muli, Chen Hongjiao, Liu Wei, Liu Yang, Wang Guopeng.  (2021)  Integrated Strategy From In Vitro, In Situ, In Vivo to In Silico for Predicting Active Constituents and Exploring Molecular Mechanisms of Tongfengding Capsule for Treating Gout by Inhibiting Inflammatory Responses.  Frontiers in Pharmacology,  12  (3287).  [PMID:34912220]
57. Yonggang Du, Ge Zhao, Gonghui Shi, Yiming Wang, Wei Li, Shitong Ren.  (2022)  Effect of crosslink structure on mechanical properties, thermal stability and flame retardancy of natural flavonoid based epoxy resins.  EUROPEAN POLYMER JOURNAL,  162  (110898).  [PMID:]
58. Lu Zhao, Hao Liu, Yingchao Wang, Shufang Wang, Dejin Xun, Yi Wang, Yiyu Cheng, Boli Zhang.  (2023)  Multimodal Identification by Transcriptomics and Multiscale Bioassays of Active Components in Xuanfeibaidu Formula to Suppress Macrophage-Mediated Immune Response.  Engineering,  20  (63).  [PMID:34815890]
59. Stoyan Dirimanov,Petra Högger.  (2019-06-15)  Screening of Inhibitory Effects of Polyphenols on Akt-Phosphorylation in Endothelial Cells and Determination of Structure-Activity Features..  Biomolecules,  ((6)):   [PMID:31195734]

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