Luteolin - ≥98%(HPLC), high purity , CAS No.491-70-3

Item Number

L107329

• Synonyms: luteolin|491-70-3|Digitoflavone|Luteolol|2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one|3',4',5,7-Tetrahydroxyflavone|Flacitran|Luteoline|Salifazide|Weld Lake|Yama kariyasu|Cyanidenon 1470|5,7,3',4'-Tetrahydroxyflavone|Bismite|C.I. Natural Yellow
• Specifications & Purity: Moligand™, ≥98%(HPLC)
• Biochemical and Physiological Mechanisms: Anti-inflammatory, antioxidant and free radical scavenger. Inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 activation. Also inhibits TNF-α-induced COX-2 expression. Antiproliferative and chemopreventative
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Grade: Moligand™
• Note: 250mg售完停产

Product Description

Luteolin is an antioxidant flavonoid and a free radical scavenger. It inhibits rat liver cytosolic glutathione S-transferase activity and soybean and reticulocyte 15-LO (15-lipoxygenases). Luteolin also shows cytotoxic effects on Raji lymphoma cells. Incubation of the non-tumor cell line C3H10T?CL8 with luteolin results in induction of p53 accumulation and apoptosis, with apoptosis occurring at the G2/M phase of the cell cycle. Luteolin is an inhibitor of Cot, PDE1-5, c-Src, HDAC, Maltase-glucoamylase, Topo I, PKC ε, Fatty Acid Synthase, PPAR γ and MMP.
An inhibitor of glutathione S-transferase and 15-LO.