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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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L288735-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $321.90 | |
L288735-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,305.90 |
Selective CCK2antagonist
Synonyms | 147523-65-7|LY 288513|LY288513|LY-288513|UNII-470GWP2CA0|1-Pyrazolidinecarboxamide, N-(4-bromophenyl)-3-oxo-4,5-diphenyl-, (4S,5R)-|470GWP2CA0|LY262691|CHEMBL333081|(4S,5R)-N-(4-bromophenyl)-3-oxo-4,5-diphenylpyrazolidine-1-carboxamide|(4S,5R)-N-(4-BROMOP |
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Specifications & Purity | Moligand™, ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Selective CCK2receptor antagonist (IC50values are 16 and > 30,000 nM for CCK2and CCK1respectively). Displays anxiolytic and antipsychotic propertiesin vivo. |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | Moligand™ |
Action Type | ANTAGONIST |
Mechanism of action | Antagonist of CCK 2 receptor |
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IUPAC Name | (4S,5R)-N-(4-bromophenyl)-3-oxo-4,5-diphenylpyrazolidine-1-carboxamide |
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INCHI | InChI=1S/C22H18BrN3O2/c23-17-11-13-18(14-12-17)24-22(28)26-20(16-9-5-2-6-10-16)19(21(27)25-26)15-7-3-1-4-8-15/h1-14,19-20H,(H,24,28)(H,25,27)/t19-,20-/m0/s1 |
InChi Key | LMUQHXHWJWQXSD-PMACEKPBSA-N |
Canonical SMILES | C1=CC=C(C=C1)C2C(N(NC2=O)C(=O)NC3=CC=C(C=C3)Br)C4=CC=CC=C4 |
Isomeric SMILES | C1=CC=C(C=C1)[C@H]2[C@@H](N(NC2=O)C(=O)NC3=CC=C(C=C3)Br)C4=CC=CC=C4 |
Alternate CAS | 147523-65-7 |
PubChem CID | 2802894 |
MeSH Entry Terms | 1-(4-bromophenylaminocarbonyl)-4,5-diphenyl-3-pyrazolidinone;LY 262691;LY 288512;LY 288513;LY-262691;LY-288512;LY262691;LY288513 |
Molecular Weight | 436.3 |
CAS Registry No. | 147523-65-7 |
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ChEMBL Ligand | CHEMBL117281 |
PubChem CID | 6956374 |
GPCRdb Ligand | LY-288513 |
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Solubility | Solvent:DMSO, Max Conc. mg/mL: 43.63, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 43.63, Max Conc. mM: 100 |
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