LY 78335 - 98%, high purity , CAS No.39959-66-5

  • ≥98%
Item Number
L287279
Grouped product items
SKUSizeAvailabilityPrice Qty
L287279-10mg
10mg
In stock
$96.90
L287279-50mg
50mg
In stock
$360.90
L287279-250mg
250mg
In stock
$1,620.90
L287279-1g
1g
In stock
$5,832.90

Phenylethanolamine-N-methyltransferase inhibitor

Basic Description

Synonyms(y)-2,3-Dichloro-alpha-methylbenzylamine hydrochloride | DTXSID80474684 | 1-(2,3-dichlorophenyl)ethanamine;hydrochloride | 1-(2,3-Dichlorophenyl)ethanamine hydrochloride | CS-0028369 | EU-0100476 | CCG-221780 | (+/-)-2,3-Dichloro-alpha-methylbenzylamine h
Specifications & Purity≥98%
Biochemical and Physiological MechanismsHigh affinity inhibitor of phenylethanolamine-N-methyltransferase (PNMT) (Ki= 0.09μMin vitro). Suppresses the release of growth hormone in anin vivorat model.
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
Product Description

Product introduction

phenylethanolamine-N-methyltransferase (PNMT) inhibitor

Associated Targets(Human)

GLA Tclin Alpha-galactosidase A (5444 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PNMT Tchem Phenylethanolamine N-methyltransferase (540 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 1-(2,3-dichlorophenyl)ethanamine;hydrochloride
INCHI InChI=1S/C8H9Cl2N.ClH/c1-5(11)6-3-2-4-7(9)8(6)10;/h2-5H,11H2,1H3;1H
InChi Key FQTXPVLCCDQRHY-UHFFFAOYSA-N
Canonical SMILES CC(C1=C(C(=CC=C1)Cl)Cl)N.Cl
Isomeric SMILES CC(C1=C(C(=CC=C1)Cl)Cl)N.Cl
PubChem CID 11957540
Molecular Weight 226.53

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
G2219639Certificate of AnalysisJun 13, 2022 L287279
G2219657Certificate of AnalysisJun 13, 2022 L287279
G2219979Certificate of AnalysisJun 13, 2022 L287279
G2219981Certificate of AnalysisJun 13, 2022 L287279

Chemical and Physical Properties

SolubilitySolvent:water, Max Conc. mg/mL: 22.65, Max Conc. mM: 100 with gentle warming; Solvent:DMSO, Max Conc. mg/mL: 22.65, Max Conc. mM: 100 with gentle warming

Related Documents

Solution Calculators