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LY2452473 - 98%, high purity , Androgen Receptor modulator, CAS No.1029692-15-6, Androgen Receptor modulator

≥98%

CAS#: 1029692-15-6
Formula: C₂₂H₂₂N₄O₂
Molecular Weight: 374.44
PubChem CID: 24963749

Item Number

L646443

Grouped product items
SKU	Size	Availability	Price
L646443-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$110.90
L646443-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$150.90
L646443-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$250.90
L646443-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$400.90

View related series

Androgen Receptor Vitamin D Related/Nuclear Receptor

Basic Description

Synonyms	1029692-15-6 \| LY2452473 \| LY-2452473 \| Isopropyl (2S)-7-Cyano-4-(pyridin-2-ylmethyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-2-ylcarbamate \| XKW9MYF94Y \| OPK-88004 \| TT-701 \| (S)-Isopropyl (7-cyano-4-(pyridin-2-ylmethyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-2-yl)carbamat
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	LY2452473 is an orally bioavailable, selective androgen receptor modulator (SARM).
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Action Type	MODULATOR
Mechanism of action	Androgen Receptor modulator
Product Description	LY2452473 is an orally bioavailable, selective androgen receptor modulator (SARM). In Vivo LY2452473 is a selective androgen receptor modulator being developed for the treatment of disorders related to hypogonadism. LY2452473 is absorbed rapidly (time to reach maximum plasma concentration for both LY2452473 and total radioactivity is 2-3 h) and cleared slowly (plasma terminal t 1/2 of 27 h for LY2452473 and 51 h for the total radioactivity) . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Androgen receptor

Associated Targets(Human)

CYP2C8 Tchem Cytochrome P450 2C8 (1492 Activities)

Discover Target: CYP2C8

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)

Discover Target: CYP2D6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)

Discover Target: CYP1A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A5 Tclin Cytochrome P450 3A5 (525 Activities)

Discover Target: CYP3A5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)

Discover Target: CYP2C9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)

Discover Target: CYP2C19

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2E1 Tchem Cytochrome P450 2E1 (2174 Activities)

Discover Target: CYP2E1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2B6 Tchem Cytochrome P450 2B6 (1338 Activities)

Discover Target: CYP2B6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Homo sapiens (32628 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2J2 Tchem Cytochrome P450 2J2 (258 Activities)

Discover Target: CYP2J2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasma (328 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	propan-2-yl N-[(2S)-7-cyano-4-(pyridin-2-ylmethyl)-2,3-dihydro-1H-cyclopenta[b]indol-2-yl]carbamate
INCHI	InChI=1S/C22H22N4O2/c1-14(2)28-22(27)25-17-10-19-18-9-15(12-23)6-7-20(18)26(21(19)11-17)13-16-5-3-4-8-24-16/h3-9,14,17H,10-11,13H2,1-2H3,(H,25,27)/t17-/m0/s1
InChi Key	IHIWYQYVBNODSV-KRWDZBQOSA-N
Canonical SMILES	CC(C)OC(=O)NC1CC2=C(C1)N(C3=C2C=C(C=C3)C#N)CC4=CC=CC=N4
Isomeric SMILES	CC(C)OC(=O)N[C@H]1CC2=C(C1)N(C3=C2C=C(C=C3)C#N)CC4=CC=CC=N4
Alternate CAS	1029692-15-6
PubChem CID	24963749
MeSH Entry Terms	LY2452473;N-((2S)-7-cyano-4-(2-pyridylmethyl)-2,3-dihydro-1H-cyclopenta(b)indol-2-yl)carbamate
Molecular Weight	374.44

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LY2452473 - 98%, high purity , Androgen Receptor modulator, CAS No.1029692-15-6, Androgen Receptor modulator

Basic Description

Product Properties

Associated Targets(Human)

Associated Targets(non-human)

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

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