LYN-1604 hydrochloride - ≥98%, high purity , CAS No.2088939-99-3

  • ≥98%
Item Number
L303086
Grouped product items
SKUSizeAvailabilityPrice Qty
L303086-1mg
1mg
In stock
$105.90
L303086-5mg
5mg
In stock
$362.90
L303086-10mg
10mg
In stock
$593.90
L303086-25mg
25mg
In stock
$1,329.90
L303086-50mg
50mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$2,393.90
L303086-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$3,433.90
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Autophagy ULK

Basic Description

Specifications & Purity≥98%
Biochemical and Physiological MechanismsLYN-1604 is a potent ULK1 (UNC-51-like kinase 1; Autophagy-related protein 1 homolog) activator (EC50 = 18.94 nM; 1.96-fold activation at 100 nM) that induces ULK complex (ULK1-mATG13-FIP200-ATG101)-dependent death in the triple-negative breast cancer (TN
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads

Associated Targets(Human)

ULK1 Tchem Serine/threonine-protein kinase ULK1 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MDA-MB-231 (73002 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 2-[bis(2-methylpropyl)amino]-1-[4-[2-(2,4-dichlorophenyl)-2-(naphthalen-2-ylmethoxy)ethyl]piperazin-1-yl]ethanone
INCHI InChI=1S/C33H43Cl2N3O2/c1-24(2)19-37(20-25(3)4)22-33(39)38-15-13-36(14-16-38)21-32(30-12-11-29(34)18-31(30)35)40-23-26-9-10-27-7-5-6-8-28(27)17-26/h5-12,17-18,24-25,32H,13-16,19-23H2,1-4H3
InChi Key DVNVYWLKGWAELS-UHFFFAOYSA-N
Canonical SMILES CC(C)CN(CC(C)C)CC(=O)N1CCN(CC1)CC(C2=C(C=C(C=C2)Cl)Cl)OCC3=CC4=CC=CC=C4C=C3
Isomeric SMILES CC(C)CN(CC(C)C)CC(=O)N1CCN(CC1)CC(C2=C(C=C(C=C2)Cl)Cl)OCC3=CC4=CC=CC=C4C=C3
PubChem CID 131801113
Molecular Weight 657.54

Certificates

Certificate of Analysis(COA)

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6 results found

Lot NumberCertificate TypeDateItem
L2101358Certificate of AnalysisSep 13, 2024 L303086
L2101360Certificate of AnalysisSep 13, 2024 L303086
L2101369Certificate of AnalysisSep 13, 2024 L303086
L2101370Certificate of AnalysisSep 13, 2024 L303086
L2101371Certificate of AnalysisSep 13, 2024 L303086
L2101482Certificate of AnalysisSep 13, 2024 L303086

Chemical and Physical Properties

SolubilityDMSO: 2 mg/mL, clear

Related Documents

Solution Calculators