5-Methylcytidine - 99%, high purity , CAS No.2140-61-6

  • ≥99%
Item Number
M168577
Grouped product items
SKUSizeAvailabilityPrice Qty
M168577-250mg
250mg
In stock
$78.90
M168577-1g
1g
In stock
$242.90
M168577-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,090.90
M168577-10g
10g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,962.90

Endogenous modified nucleoside. DNA methylation marker.

Basic Description

SynonymsNSC-363933 | M1931 | s6138 | 5-Methylcytidine | 5-methyl-cytidine | DTXSID401016977 | 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2-dihydropyrimidin-2-one | AC-32357 | AM83948 | EINECS 218-390-8 | Adenosine receptor ago
Specifications & Purity≥99%
Biochemical and Physiological MechanismsEndogenous modified nucleoside. DNA methylation marker. 5-methylcytosine derivative. 5-methyltransferase Trm4 substrate. Accumulates in uncharged histone tRNA molecules when 5-methyltransferase Trm4 is depleted.Endogenous modified nucleoside. DNA methylat
Storage TempRoom temperature
Shipped InNormal
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(non-human)

L1210 (27553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L1210/ara C (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488186745
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488186745
IUPAC Name 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidin-2-one
INCHI InChI=1S/C10H15N3O5/c1-4-2-13(10(17)12-8(4)11)9-7(16)6(15)5(3-14)18-9/h2,5-7,9,14-16H,3H2,1H3,(H2,11,12,17)/t5-,6-,7-,9-/m1/s1
InChi Key ZAYHVCMSTBRABG-JXOAFFINSA-N
Canonical SMILES CC1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O
Isomeric SMILES CC1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
PubChem CID 92918
Molecular Weight 257.24

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
L2110174Certificate of AnalysisSep 21, 2023 M168577
A2309471Certificate of AnalysisJan 13, 2023 M168577
L2201233Certificate of AnalysisDec 09, 2022 M168577
D1903148Certificate of AnalysisDec 07, 2022 M168577
I2212116Certificate of AnalysisJul 14, 2022 M168577
I2212117Certificate of AnalysisJul 14, 2022 M168577
I2212118Certificate of AnalysisJul 14, 2022 M168577
I2212119Certificate of AnalysisJul 14, 2022 M168577

Chemical and Physical Properties

SolubilitySoluble in water
Specific Rotation[α]15° (C=2,H2O)
Melt Point(°C)211 °C(dec.)

Related Documents

Citations of This Product

1. Sirui Zhu, Yuanyuan Li, You Wu, Yanan Shen, Ying Wang, Yujie Yan, Weijun Chen, Qiong Fu, Yirong Wang, Xiang Yu, Feng Yu.  (2023)  The FERONIA-YUELAO module participates in translational control by modulating the abundance of tRNA fragments in Arabidopsis.  DEVELOPMENTAL CELL,      [PMID:37977150] [10.1016/j.devcel.2023.10.014]

References

1. Sirui Zhu, Yuanyuan Li, You Wu, Yanan Shen, Ying Wang, Yujie Yan, Weijun Chen, Qiong Fu, Yirong Wang, Xiang Yu, Feng Yu.  (2023)  The FERONIA-YUELAO module participates in translational control by modulating the abundance of tRNA fragments in Arabidopsis.  DEVELOPMENTAL CELL,      [PMID:37977150] [10.1016/j.devcel.2023.10.014]

Solution Calculators